ISSN:1784-3286    

DOI:10.1080/17843286.1989.11718007

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryThis study analyses retrospectively the plasma level of neuron-specific enolase (NSE) performed in 236 patients presenting for the diagnosis of a bronchopulmonary disease.Taking a cut off on 15ng/L,61 (64 %) of the 95 patients sharing a small cell lung cancer (SCLC) (45 % of those with a limited disease and 90 % with an extensive disease) hut 8(13%) of 60 with a non small cell lung cancer patients and 0 % of those with a benign bronchopulmonary disease showed an abnormal value of NSE.Therefore in this group of patients, the diagnosis of SCLC could be assessed with a sensitivity of 64% and aspecificityof 94% in patients with an NSE plasma level above 15 Mg/LIn addition, the interest of sequential dosages of NSE for the monitoring of SCLC patients is also stressed.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11718008

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryThe aim of the study was to evaluate the effect of a computer-assisted insulin delivery on the glycemic control of type I unstable diabetic patients. 6 subjects, who already received 2–4 daily insulin injections, were treated with a pocketsize microprocessor device for periods lasting 2–14 months. The total daily in sulin doses remained unchanged during the experimental period. However, the percentage of regular insulin decreased significantly from 63±3% to 47±7 % (p<0.05). HbAl levels decreased from 10.1±0.6% to 9.4±0.4% after 2 months computer (p<0.05). However, in the 2 patients who used th e device for 11–14 months, the over all glycemic control was comparable during the basal and experimental periods. Hypoglycemic episodes were not increased.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11718009

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryWe present a sero-epidemiological study of 190 Belgian cases of Lyme borreliosis, a multi systemic disease caused by the spirochaete Borrelia burgdorferi and transmitted by a tick bite. The whole spectrum of clinical pictures was observed in these patients, including«erythema chronicum migrans»(63%), neurological in volvement (47%) and arthritis (22%), frequently in combination.Our results are compared to findings in other countries.Among the 437Ixodes ricinusticks collected in the Sambre and Meuse valleys around Namur, we discovered 43 ticks (9.8%) with spirochaetes in the midgut. The ecology of these arthropods ex plains why this infection is more prevalent in the spring and the summer. Perhaps for the same reason, the incidence ranges from low near the coast to medium in the central part and high in the wooded south-eastern part of Belgium.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11718010

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummarySeven cases of granulocytic sarcoma (GS) with different clinical presentations are reported. Granulocytic sarcoma is diagnosed by tumorbiopsy. The antilysozy me immunoperoxydase technique and the ASD chloroacetate esterase staining are used to confirm the diagnosis. The recent development of immunohistological staining, for demonstration of intra-cellular or surface antiens, is also use ful to recognize GS.The prognostic significance of GS is di sc ussed. For isolated GS, early aggressive treatment with chemotherapy and local radiotherapy is proposed.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11718011

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryA patient on treatment with Dpenicillamine developed aphtoid ulcers of the oesophagus, which healed rapidly after withdrawal of this drug.The mechanism of these probably drug-induced oesophageal ulcerations is discussed.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11718012

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryWe report a case of acute haemolytic anaemia complicating infectious mononucleosis in a 19-year old male. There was no evidence for an immune haemolysis and red cell studies revealed a previously undiagnosed congenital spherocytosis.We discuss this rare presentation.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11718013

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummarySix days after initiating therapy with allopurinol, toxic epidermal necrolysis developed in a 73-year-old man with renal failure. It was responsible for a generalized vasculitis and gastrointestinal bleeding ultimately leading to death.The authors emphasize the need for a careful evaluation before prescribing this medication, particularly in patients with renal failure.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11718014

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryA 57-year-old man with a history of pulmonary asbcstosis was incidentally found to have benign mesothelial hyperplasia of the peritoneum at hernia repair. Five months later he developed a Coombs positive haemolytic anaemia of the IgG-C3d type caused by non specific IgG antibodies. At that time no underlying cause for the anaemia was found. The anaemia responded to steroids, but remained steroid dependent. Six months after the diagnosis of the anaemia, a malignant peritoneal mesothelioma was found at laparotomy. The association between malignant mesothelioma and autoimmune haemolytic anaemia has been reported on one previous occasion. The description of a second case suggests that the association is not purely coincidental and that malignant mesothelioma should be added to the list of solid tumours that can be associated with autoimmune haemolytic anaemia. The finding of red blood cells coated with IgG and C3d in this as well as in other cases adds further evidence to the hypothesis that a quinidine type mechanism of haemolysis might be responsible for Coombs positive haemolytic anaemia associated with solid tumours.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11718015

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor

摘要:

SummaryWe report a case of diversion rectocolitis, an inflammatory process that frequently develops in the distal blind colorectum, after surgical diversion of the fecal stream. Since the endoscopic and histologic findings closely resemble those of inflammatory bowel disease, the differential diagnosis can be difficult. However, the inflammation permanently resolves after surgical reanastomosis. Because diversion colitis can also be treated effectively by local application of short-chain fatty acids, it has been postulated that a local nutritional deficicncy, resulting from the absence of these acids, triggers the inflammation.

ISSN:1784-3286    

DOI:10.1080/17843286.1989.11718016

出版商:Taylor&Francis    

年代:1989

数据来源: Taylor