摘要:

SummaryIn more than half the cases studied, the authors have observed a discrepancy between the bacteriological examination of the sputum and that of the secretion obtained aseptically from the bronchi.They criticize the practice of performing routine susceptibility tests to antibiotics on the sputum.They attract attention on the high rate of incidence of sterile bronchial smears, which witnesses the resistance of bronchial mucosa towards infection. They analyse the microbiological flora found in various clinical groups.They advise to obtain secretion through a bronchoscope whenever the evolution of a lung infection is not conform to criteria established on clinical grounds.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717693

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

SummaryIn two cases reports of malignant lymphoma, the surgical treatment had very remarkable results.In one of die cases the resection of cervical lymphomas and subsequent radiotherapy was followed by an apparent complete remission lasting since thirteen years.The authors discuss the role of surgery in selected cases of malignant lymphoma.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717694

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

SummaryThe indications and dosages of the various cytostatic drugs used in the treatment of lymphomas and reticuloses are discussed.Röntgen therapy remains the first choice treatment for this group of diseases. Chemotherapy is indicated only for specific clinical situations, such as mediastinal involvement with severe anoxia, compression of the spinal cord or widespread generalization. In acute mediastinal or spinal cord involvement, chemotherapy does not exacerbate the symptoms for this treatment does not increase, even temporarily, congestion of the lymph nodes. The indication for chemotherapy in widespread generalization is obvious.In circumscribed involvements, the cytostatic drugs are absolutely contra-indicated for they facilitate relapses«in situ»and shorten the duration of the disease. Moreover, improper chemotherapy inhibits patient’s auto-immunization. Finally, the cytostatic compounds are toxic to tissues with marked mitotic activity, such as the bone marrow and the gastro-intestinal tract. It follows that therapeutic are close to toxic doses.Cytostatic drugs can render the patient more susceptible to Röntgen therapy. Another indication for chemotherapy is local application in the treatment of pleural effusion where general absorption of the drug is avoided and a local effect simultaneously obtained.Brief mentions are made of the use of cytostatic drugs during pregnancy and of their indications in combination with bone marrow transfusions.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717695

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

SummaryThe therapeutic orientation tests, which are indispensable during the preliminary stage, need confirmation through severely controlled, more individual tests. In case where strictly objective evaluation criteria are lacking, a comparison between the new drug and a placebo or a standard-drug seems necessary; the formation of comparable groups without arbitrary selection and the choice of a depersonified psychological approach of the patient will allow the clinician to estahlish a correct statistical analysis of his results. The experimental scheme and the adequate statistical method will be selected with regard to the practical organization possibilities.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717696

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor