ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717953

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummarySevere iodine-induced thyrotoxicosis may pose a clinical dilemma because of its prolonged refractoriness to most forms of drug therapy. Plasmapheresis was used in five patients with iodine-induced thyrotoxicosis caused by homeopathic drugs, radiographic contrast agents and amiodarone. in two patients with underlying Graves’disease, several months of treatment with high doses of antithyroid drugs and 13-blockers did not improve the thyrotoxicosis. Plasmapheresis eventually resulted in a rapid decline of peripheral thyroid hormone levels and euthyroidism was achieved in one patient. Nevertheless no long term beneficial effect could be demonstrated since both patients further required other therapy. In three patients witli amiodarone-induced thyrotoxicosis, of whom two were in a life-threatening situation, plasmapheresis was able to restore euthyroidism in a short period of time. 1 lowcver, our observations suggest that plasmapheresis alone cannot cure iodine-induced thyrotoxicosis unless other therapeutic agents are added firstly to prevent further synthesis of thyroid hormones (antithyroid drugs) and secondly to block the release of preformed thyroid hormones from the thyroid gland (corticosteroids and iodine).

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717954

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummarySarcoidosis can involve the thyroid but is rarely associated with thyrotoxicosis.We report the case of a 36-year old woman with sarcoidosis proved by thyroid histology, who presented with an association of drug resistant hyperthyroidism and stage 2 pulmonary involvement which evolved almost simultaneously.There is probably a pathogenic relation between both syndromes; the real mechanism is still unknown.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717955

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryThe observation in Brussels of a ease of kala azar imported from Spain led us to the following considerations: l°kala azar remains sometimes undiagnosed or clinically confused with malignant lymphoma or leukaemia;2°diagnosis of kala azar must be evoked whenever medical history reveals a stay in endemic regions; in this respect, clinicians must be aware that kala azar is endemic in all the mediterranean urea, including southern France; 3°for the last 15 years, in most of the mediterranean countries, kala azar seems to occur at least as frequently in adults as in children; 4°the clinical expression of the disease may be mild at the beginning: splenomegaly may be discrete, hypergammaglobulinaemia may be lacking; 5°definite diagnosis is based on the discovery of the parasite; bone marrow aspiration represents the safest and simplest diagnostic procedure; 6°the discrepancy in frequency of subclinical and full-blown forms of infection byLeishmania donovaniraises a fundamental question, not completely resolved at the present time: does a latent immunodeficient state favour the development of severe forms of kala azar ?

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717956

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryModerate resistance to ceftazidime (MIC 4–8mg/l) was detected in strains ofKlebsiella pneumoniaeand Escherichia coliisolated from several patients in the intensive care unit. Moreover, from one of these patients which was treated with ceftazidime, an isolate ofK. pneumoniaethat displayed high-level resistance to this antibiotic (MIC 256 mg/l) was subsequently isolated. Both the low-level and high-level resistance to ceftazidime were self-transmissible to a sensitive strain ofE. coliK 12. Resistance to gentamicin, tobramycin, tetracycline, sulfonamide and trimethoprim was co-transferred in all cases. The activity of the B-lactam antibiotics was significantly enhanced by combination with clavulanic acid.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717957

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryThe effects on pulmonary function of removal of bullae occupying at least 30 per cent of a hemithorax are reported in 15 patients, 10 of whom had associated chronic obstructive lung disease. All patients with dyspnea improved symptomatically after surgery. Lung function, measured six to twelve months after surgery, was significantly improved: mean (±I SD) FEV, preoperative was 48±26% predicted and postoperative 70±26 % predicted (p<0.001); Pa02preoperative 66±9 mm Hg vs. postoperative 78±10 mm Hg (p<0.05). The largest increase of FEV, was obtained in patients with giant bullae and only slight generalised emphysema. In the seven patients with a follow-up of two to five years after surgery, the mean postoperative annual decline in FEV, was 49±51 ml.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717958

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryWe report an unusual evolution of heterozygous Fabry’s disease. Progressive renal failure occurred in a 45-year-old woman. Endstage renal failure in the fourties is usually observed in hemizygous male patients with Fabry’s disease but is unexpected in heterozygous females. In the present case, tuberculosis induced unilateral hydronephrosis was also found and could have precipitated renal failure.The association between Fabry’s disease and renal tuberculosis has been previously reported. Nevertheless a definitive relationship between both conditions is still not demonstrated.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717959

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryTwo paucisymptomatic (peri)hepatic tuberculous abscesses were diagnosed in a 20-year old Maroecan woman, by ultrasound directed percutaneous aspiration.Whereas previous reports stressed the importance of open surgical or percutaneous drainage, this case proves that it is possible to cure tuberculous hepatic abscesses with systemic tuberculostatics only.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717960

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryWe describe a 64-year-old man with severe pretibial myxedema in whom classical therapy with local applications of fluocinolone acetonide was u nsucccssful. Plasmapheresis followed by immunosuppressive therapy (azathioprinc) resulted in complete and long-lasting improvement of the skin lesions. This therapeutical regimen therefore may be of value in severe therapy-resistant pretibial myxedema.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717961

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryThe authors report a case of pituitary apoplexy whose sole clinical manifestation was painful ophtalmoplegia. No other neurological, endocrine or visual symptoms were present. The classic investigations (radiological findings as computed tomography, endocrine and visual investigations, biology) were normal. The reasons of this are the small size of the pituitary adenoma, the absence of upward enlargment or secretion. This case illustrates the carefulness necessary before concluding to the Tolosa-Hunt syndrome and the ophthalmoplegia migraine, which are diagnoses of exclusion of painful ophthalmoplegia. Many other lesions can simulate their clinical manifestations.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717962

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor