摘要:

SummaryFolic acid activity was simultaneously assessed in serum and cerebrospinal fluid (CSF) in 51 aged patients (twice in 3 of them). Mean levels of folic acid activity in CSF and serum were 21.83±9.57 and 11.03±4.99 ng/ml respectively; mean ratio of the two values was 1.98; a positive correlation between serum and CSF folic acid concentrations was observed (P<0.01). Folic acid partition between serum and CSF varies according to the category of causal diseases. In patients without anemia and without major neurological syndrome the CSF/serum folic acid ratio is 1.85; it is 2.39 and 2.44 in ncuropsychiatric patients, and 1.55 in anemic individuals; mean CSF folic acid levels differ significantly in the last two groups of patients (P<0.05). Folic acid partition between body stores and nervous system is probably not automatically regulated in constant proportions, but is apparently governed by a complex mechanism.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716739

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummarySensitivity to various antibiotics was testedin vitrofor different pathogenic microorganisms (Staphylococcus aureus, E. coli, Klebsiella-Enlerobactergroup,ProteusandPseudomonas aeruginosa).These bacteria were isolated in a cancer hospital over a period of four months. The results are presented and the meaning for the treatment of infectious diseases is discussed.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716740

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummaryIn our laboratory we use a modification of Westergren’s classical method for erythrocyte sedimentation rate determination. Five ml of blood are collected in a test tube containing heparin solution. This heparinized blood is afterwards diluted with sodium citrate solution. Several aspects of this method have been studied statistically with results from heallhy young individuals (65 males, 172 females).It was found that :1) reproductibility is good;2) results are apparently not influenced by a greater volume of blood in the test tube;3) erythrocyte sedimentation rate values with this method usually run parallel with classical Westergren values, although it is necessary to«translate»the usual norms. It was found that a limit-value of 8 mm for men (classical method) corresponds with 13 mm with this modified method and the similar limit of 10 mm becomes 18 mm for females.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716741

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummaryA case of chronic pancreatitis complicated by pancreatic abscess is deported. The abscess fistulised spontaneously into mediastinum, leading to bilateral purulent pleurisy. Pancreatic duct drainage into intestinal lumen and antibiotherapy were followed by recovery. Pertinent literature is reviewed.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716742

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummaryThe clinical features of a case of bacterial endocarditis superimposed on a congenital ventricular septum defect in a 54 year old man are presented.Aclinobacillus actinomycetemcomitanswas repeatedly isolated from the blood and the patient was successfully treated with penicillin and streptomycin. Our observation is the second such infection reported in detail from the European continent.Other published observations of endocarditis due to this organism, together with the bacteriologic characteristics of the bacterium are biefly discussed.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716743

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummaryCells take part in acid-base equilibrium regulation. At most 15 mEq H+ions per kg are neutralized during acute acidosis in man or in dog; 50 % of this load are neutralized by cellular buffers. The amount of buffers set in during chronic acidosis is far more important. It is essentially supplied by the skeleton. Intracellular pH (pH1) measurement in mammals may be accomplished by two types of techniques : indirect, based on the distribution of a weak acid or base, or direct, using glass microelectrodes. Indirect methods, using HCO3-/CO2system or dimethyl-oxazolidinedione (DMO), yield pH1values (muscular cells) close to 7 for extracellular pH (PHE) of 7.40. They also demonstrate the lack of linear relationship between pH1and pHE, suggesting on autonomous regulation of pH1, linked with cellular metabolism. Direct methods yield pH1values (muscular cells) close to 6 for pHEof 7.40/, and membrane potential of—90 mV. They demonstrate a simple linear relationship between pH1and pHE, which suggests that H+ions distribution across cellular membrane is largely influenced by Donnan equilibrium. Discrepancies between the data obtained with direct and indirect methods are due either to systemic error in one of the two methods, or by the fact that both techniques do not measure the same pH, intracellular pH being possibly not homogeneous.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716744

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor