摘要:

SummaryDuring the initial phase of a prospective cardiovascular epidemiological study, the dosage of the serum cholesterol level was performed in 960 male subjects, most of them having a sedentary life, age varied from 40 to 59, all persons employees of a great Brussels' parastatal organization.The distribution we observe is characterized by a mean level of 240,4 mg/ml with a standard deviation of 43.These values are very similar to those found in U.S.A., in comparable populations. A significant increase of the mean cholesterol level is observed in subjects with ischaemic heart disease. The same is found in subjects suffering from hypertension. There is a low but significant correlation between the cholesterol level and the arterial pressure, especially diastolic, the stature and the corpulence index, particularly the relative weight, the Davenport index and the skinfold thickness.The relation between the cholesterol level and thearcus senilisis very significant. No significant correlation is observed with the weight or the age, although the mean cholesterol level is significantly higher during the sixth than during the fifth decade.Generally, these data are in agreement with those established in other countries having a high standard of life, as far as the studied populations are homogenous and sufficiently numerous. The importance of the associations we found is still more striking, since the serum cholesterol level has a strong variability and since there is no healthy reference population, neither from the clinical, nor from the biological point of view.

ISSN:1784-3286    

DOI:10.1080/17843286.1967.11716648

出版商:Taylor&Francis    

年代:1967

数据来源: Taylor

摘要:

SummaryThe clinical diagnosis of fatty liver is difficult and this disease is often unknown.The presence of an hepatomegaly (sometimes painful) accompanied by subicterus, vomiting, emaciation, edema, must notwithstanding evocate this disease, particularly in ethylism, dia!>etes, obesity, deficiency, anoxia.Laboratory does not reveal any typical elements except for hypoalbuminaemia, byperglobulinaemia, hyperbilirubinaemia and retention of bromesulfone-phtalein.Laparoscopy is very helpful, because the macroscopical aspect of the liver is often evocative. Liver biopsy under visual control of hemostasis is possible, which tlisminishes the risk of this investigation. Histology will confirm the diagnosis.However, an early diagnosis is necessary, because the elimination of aetiological factors leads to recovery.The rapid reversibility of fatty liver under normoprotidlcal diet, such as in Kwashiorkor, is well known. The early elimination of the toxic factor (mainly ethanol) and a well balanced diet result in normalisation of the liver structure, as has been histologically demonstrated by repeated biopsies. On the other hand, the maintenance of the toxic effect or its late or incomplete suppression can lead to liver cirrhosis : several of our cases confirmed this observation.Fatty liver of juvenile diabetes, which is easily reversible by insulin therapy, must be differentiated from fatty liver of olicse diabetic patients, which is curable by low calories low fat diet.It is stressed that steatosis can lead to cholostatie jaundice. Laparoscopy, biopsy, together with cholangiography or the«manœuvre de Royer»will sometimes allow the patient to avoid the danger of a narcosis for laparotomy.

ISSN:1784-3286    

DOI:10.1080/17843286.1967.11716649

出版商:Taylor&Francis    

年代:1967

数据来源: Taylor

摘要:

SummaryIt is impossible to clearly define the normal antistreptolysin O titer; in addition the great deal of non specific antistreptolysin-like activities shown by the beta-lipoprotein justifies their elimination, allowing the titration of the specific antistreptolysin. The presence of pathologic non-specific antistreptolytic titers will guide the investigator towards hepatic or renal diseases, metabolic disturbance of the lipidic fraction or tuberculosis. In doubtful cases, the reality of immunologic response toStreptococcusagression will be demonstrated by the titration of the antistrcptoprotcin-M which is quite specific and shows a better persistance than the antistreptolysin-O. This titration can demonstrate an eventual potential renal toxicity of the infectingStreptococcuswhich is coarsely typed.

ISSN:1784-3286    

DOI:10.1080/17843286.1967.11716650

出版商:Taylor&Francis    

年代:1967

数据来源: Taylor

摘要:

SummaryConstitutional disturbances of the«prothrombin complex»concern the coagulation factors II, V, VII and X. A congenital deficiency of one of these clotting factors is rare and seldom total. The partial decreased level of one of the factors involved has a limited influence on the overall or globalin vitrocoagulation tests although the haemorrhagic syndrome might be evident. More specific tests have to be performed to diagnose correctly these unusual blood disorders and require the help of a specialised laboratory.A congenital deficiency of one component of the«prothrombin complex»follows an autosomal recessive hereditary pattern. This explains why the disease is apparently rare and overt in homozygotes only, and provided the abnormal gene has a high penetration. As hétérozygotes have only a minor deficiency, thev are not afflicted with bleeding and these individuals are usually not detected by the routine tests in blood coagulation.

ISSN:1784-3286    

DOI:10.1080/17843286.1967.11716651

出版商:Taylor&Francis    

年代:1967

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1967.11716652

出版商:Taylor&Francis    

年代:1967

数据来源: Taylor