摘要:

SummarySix hundred forty-seven cases of acute voluntary and acidental poisoning and alcoholic intoxication have been reviewed.The purpose of this study was :to demonstrate the progressive rise of the voluntary poisoning frequency;to establish social and individual factors which might influence their frequency;to determine the most commonly encountered drugs or substances;to describe the intoxication symptoms and their severity in relation to the dose and chemical form of the toxic;to evaluate the efficacity of the therapy used comparing our results with those obtained by others.This study led to the following conclusions :Voluntary poisoning by means of various drugs are more frequent every year and are mostly seen in women.No conclusion about the influence of profession can be made.Barbiturate poisoning is the most frequent and serious one.Intensive and meticulous supportive care is, at present, the therapy of choice in most cases of acute poisoning.The mortality and the severe sequelae rates of acute intoxications are very low.

ISSN:1784-3286    

DOI:10.1080/17843286.1963.11717127

出版商:Taylor&Francis    

年代:1963

数据来源: Taylor

摘要:

SummaryFrom 1956 to 1962, 8 patients were admitted to the medical department of Brugmann Hospital, for acute CCI4intoxication.In 6 cases, intoxication followed inhalation of dry cleaners containing CCI4, used for cleaning clothes or furniture. In 2 cases, it was due to the accidental ingestion of C Cl4.The clinical features were :toxic hepatitis with moderate jaundice and high level of serum transaminases;renal failure of rather short duration.Fever and hypertension were sometimes observed. The outcome was favourable in 7 cases : 4 patients recovered without the use of the artificial kidney, and 3 after only one dialysis. One of the two patients who had ingested CCI4died from profuse haemorrhage on the fifth week after intoxication despite five dialysis.The dangers inherent to the domestic use of C Cl4-containing cleaners are re-emphasized.

ISSN:1784-3286    

DOI:10.1080/17843286.1963.11717128

出版商:Taylor&Francis    

年代:1963

数据来源: Taylor

摘要:

SummaryAfter a short survey of the pharmacological properties of barbiturates and of the clinical signs of acute barbiturate intoxication, the authors review the different methods of treatment in use.Gastric lavage and administration of classical central analeptics are actually abandoned. The use of bemegride is limited to a few rare cases of respiratory depression of central origin.The modern treatment of acute barbiturate intoxication is essentially based on the Scandinavian method of reanimation and of the alkalinisation of plasma and urine by the method of Mollaret.The aim of the reanimation is to maintain within physiological limits of respiratory, cardiovascular and renal functions until the patient awakes, to prevent secondary infection and to ensure an adequate intake of liquids, calories and electrolytes. The primordial importance of the reanimation is actually everywhere admitted. The introduction of this symptomatic treatment has permitted to reduce the mortality of acute barbiturate intoxication to less than 3 %.Plasma and urine alkalinisation accelerates the renal output of the barbiturate. The duration of the coma is therefore significantly reduced.

ISSN:1784-3286    

DOI:10.1080/17843286.1963.11717129

出版商:Taylor&Francis    

年代:1963

数据来源: Taylor

摘要:

SummaryThe symptoms of occupational lead poisoning are less and less characteristic. The diagnosis is now essentially based on the counting of red stippled cells, on porphyrinuria and on the dosage of lead in blood and urine. The interpretation of the results of these tests is discussed as well as the value of the urinary excretion test with Ca Na2E.D.T.A.The treatment with chelators is discussed and special reference is made to the possibility of versenate nephrosis.

ISSN:1784-3286    

DOI:10.1080/17843286.1963.11717130

出版商:Taylor&Francis    

年代:1963

数据来源: Taylor

摘要:

SummaryClinical and biological correlations were studied in 16 patients suffering from chronic pyelonephritis. The morphological diagnosis was established12times by renal biopsy and 4 times on surgical or autopsy material.Clinically the salient facts observed were the association of chronic pyelonephritis with diabetes mellitus in 10 cases, the existence of an otherwise unexplained hepatosplenomegaly in 3 cases. Associated hypertension was only found once in the series.Amongst the biological data, an acceleration of the sedimentation rate, an increase of theα2globulien level and a moderate hypochromic anaemia were nearly constantly noted. Renal function revealed variable alterations : Volhard concentration test and phenolsulfonephtalein elimination test were however the most frequently altered. Pyelographies showed delayed elimination for one or both kidneys with more or less modification of the pyelogram.As for the urinary examinations, in all cases, Sternheimer-Malbin pale cells were found and at a minimum concentration of 30 %. It is noticeable that in 3 cases the culture of the urine yielded no germs and that in 2 cases who had had an intensive antibiotherapy the urinary white cells output was not increased.The urine culture obtained 2 hours after renal needle biopsy was positive once in a case where the ordinary methods had shown no bacteria. The culture obtained after dipping the biopsy needle in a bacteriological medium was positive in three cases only.

ISSN:1784-3286    

DOI:10.1080/17843286.1963.11717131

出版商:Taylor&Francis    

年代:1963

数据来源: Taylor

摘要:

SummaryDuring an outbreak ofStaphylococcus aureusinfection in Brugmann Hospital, the investigation of isolated germ strains demonstrated the occurrence of a large variety of bacteriophage types. Most of them belong to group III.The pattern of bacteriophage types of all the strains isolated in the hospital is the same as that found in healthy carriers, in the nostrils of the nursing staff and in all strains isolated from staphylococcal lesions.Nevertheless, hospital infections are due, for the most part, to group III, in which most drug-resistant strains are to he found.Group I staphylococci were found in cutaneous lesions only. They kept a fairly high sensitivity to antibiotic.In this outbreak, the absence of a common source of infection implies a particularly great difficulty in eradicating the germs.

ISSN:1784-3286    

DOI:10.1080/17843286.1963.11717132

出版商:Taylor&Francis    

年代:1963

数据来源: Taylor