ISSN:1784-3286    

DOI:10.1080/22953337.1987.11719240

出版商:Taylor&Francis    

年代:1987

数据来源: Taylor

摘要:

SummaryWe describe the identification of Hantaan-related virus as the cause of 2 cases of sporadic nephritis. The main clinical characteristics and serologic observations of the disease are reported.Serological evidence of Hantaan virus infection should be sought in all acute renal failure cases, developing within a context of fever, bilateral loin pain, and transient proteinuria and haematuria.

ISSN:1784-3286    

DOI:10.1080/22953337.1987.11719241

出版商:Taylor&Francis    

年代:1987

数据来源: Taylor

摘要:

SummaryWe report four recent cases of nephritis due to Hantaan-related virus.We describe the main clinical and biological characteristics of the disease and we stress its epidemiology.The diagnosis of nephritis due to Hantaanrelated virus infection is made by serology.

ISSN:1784-3286    

DOI:10.1080/22953337.1987.11719242

出版商:Taylor&Francis    

年代:1987

数据来源: Taylor

摘要:

SummaryWe report the results of 29 diagnostic bronchofibroscopies performed from January to October 1985 in 25 immunocompromised Patients with haematologic diseases, presenting with radiographic pulmonary infiltrates of unknown aetiology.In 13 cases (13 fibroscopies) specific diagnoses were obtained: infection in 11 cases and tumoral invasion in 2 (non-Hodgkin lymphoma). This gives a specific diagnostic yield of 45 % per fibroscopy and of 52 % per patient. The infections were due to fungi in 5 cases (Candida albicansandkrusei, 3 Torulopsis glabrata), bacteria in 3 cases (Serratia marcescens, Streptococcus pneumoniae, Pseudomonas aeruginosa), fuberculosis in 2 cases, andHerpes simplex virus1 case. All investigatory procedures used at fibroscopy (virus isolation, cultures, cytohistology) have contributed to the diagnosis..12 cases (16 fibroscopies) a specific diagnosis could not be made. Infection was suspected in 8 cases (11 fibroscopies), but all‘ibroscopic investigations were negative. In 4 cases fibroscopy provided only atypical results (mostly fibrosis on histology), but other investigations provided a diagnosis: graft-versushost-disease in 2 cases and non-Hodgkin‘ymphoma in 2 cases. A specific fibroscopic d’agnosis often led to an adaptation of therapy; however, survival remained poor.Fibroscopy was well tolerated and caused no serious complications such as respiratory distress, major bleeding or pneumothorax. In no case repeated fibroscopy was useful.

ISSN:1784-3286    

DOI:10.1080/22953337.1987.11719243

出版商:Taylor&Francis    

年代:1987

数据来源: Taylor

摘要:

SummaryAn illness of abrupt onset characterized by mononucleosis-like syndrome, lymphocytic meningitis, generalized erythematous rash, pancytopenia with bone marrow hemophagocytosis, generalized lymphadenopathy and liver dysfunction revealed an acute infection due to HIV. Immunological studies showed cellular immunodeficiency (cutaneous anergia, decreased lymphoproliferative response to mitogens, inversion of the T4/T8 ratio due to expansion of the T8 subset). Histopathology of lymph node showed large germinal centers with atrophic Tcell zones. Seroconversion for HIV occured between the 4th and 5th weeks after onset of disease. CSF examination revealed lymphocytic pleiocytosis and was negative for HIV antibodies. The patient is clinically well after a follow up of 27 months, despite persistence of small lymphadenopathy and discrete immunodeficiency. She remains HIV seropositive and her circulating lymphocytes continue to harbor the virus. HIV should be considered in the differential diagnosis of mononucleosis-like syndrome and lymphocytic meningitis.

ISSN:1784-3286    

DOI:10.1080/22953337.1987.11719244

出版商:Taylor&Francis    

年代:1987

数据来源: Taylor

摘要:

SummaryDiagnosis of beta-thalasscmia minor was evoked among 9 Belgian individuals from 6 nonrelated families on the basis of microcytosis (mean MCV 67μ.3; range: 59–74μ1) and confirmed by determination of Hb A2 levels (mean 5,4%; range 3.9 to 7.1 %). Iron deficiency, another common cause of microcytosis, was excluded in 6/7 subjects. These individuals do not have clinical manifestations needing hospitalization. It has been estimated that in the Brussels region birth of one child with betathalasscmia major may be expected each year and that the cost resulting from detection programmes of carrier states would be lower than the cost for treatment of beta-thalassemia major. In view of the high numbers of immigrants in Belgium and to avoid intcmpestive iron treatment, detection of beta-thalasscmia minor must also be performed among Belgian individuals presenting with microcytosis. Two major hypotheses are proposed for explaining the presence of bcta-thalassemic gene among North European populations: spontaneous mutations or persistence of old mutations introduced during successive invasions of this country.

ISSN:1784-3286    

DOI:10.1080/22953337.1987.11719245

出版商:Taylor&Francis    

年代:1987

数据来源: Taylor

摘要:

SummaryThree patients in the same family with low fibrinogen levels have been studied. The abnormality was clinically silent. The fibrinogen level varied from 50 to 145 mg/dl. Good agreement between the various methods of fibrinogen assay was observed. Since no afibrinogenemic patient was observed in this family, the abnormality presented by these patients was classified as congenital hypofibrinogenemia. Our observation also suggests that there is an increase in fibrinogen level with age in hypofibrinogcnemic patients, as occurs in normal subjects.

ISSN:1784-3286    

DOI:10.1080/22953337.1987.11719246

出版商:Taylor&Francis    

年代:1987

数据来源: Taylor

摘要:

SummaryWe report a case of Goodpasture’s syndrome Presenting with insidious haemoptysis. Lung biopsy allowed us to reach a definite diagnosis.

ISSN:1784-3286    

DOI:10.1080/22953337.1987.11719247

出版商:Taylor&Francis    

年代:1987

数据来源: Taylor

摘要:

SummaryOut of 430 patients who were operated for coronary heart disease, 115 underwent an ergometric exercise test, a right heart catheterisation with measurement of the Pulmonary capillary wedge pressure at rest and during exercise and a coronary angiography.We have observed a relationship between the Presence and severity of angina pectoris, elecrocardiographic ST-segmcnt depression, haemodynamic PCW-pressure rise on the one hand and the angiographic severity of the coronary disease on the other. This is particularly true for left main stem lesions.The explanation for this relationship lies in the impairment of left ventricular function caused by regional disturbances of myocardial Contractility, resulting from the coronary stenosis.

ISSN:1784-3286    

DOI:10.1080/22953337.1987.11719248

出版商:Taylor&Francis    

年代:1987

数据来源: Taylor

摘要:

SummaryThe use of the organic solvents ethanol and propylene glycol in injectable nitroglycerin is potentially hazardous, because of the possibility of cardiodcpression, arrhythmias and/or coronary vasospasm; neurotoxicity and depression of the central nervous system; hyperosmolality, lactic acidosis and hemolysis, especially in patients with diminished renal function; interaction with disulfiram and compounds with a disulfiram-like action; interaction with oral antidiabetics and with heparin. Nitroglycerin itself can cause methemoglobinemia.Obviously, the use of NTG solutions containing no ethanol nor PG could solve most of the cited problems, except methemoglobinemia. However, when used in low doses (up to 150200 /xg/min) in patients with normal liver and kidney function, NTG remains a very effective and safe drug, usually free of any side-cffects. ISDN which is a watery solution without organic solvents, could be used as a safe alternative.

ISSN:1784-3286    

DOI:10.1080/22953337.1987.11719249

出版商:Taylor&Francis    

年代:1987

数据来源: Taylor