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1. |
Calcitonin: What Is New In 1992 |
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Acta Clinica Belgica,
Volume 47,
Issue 2,
1992,
Page 77-81
BodyJ.J.,
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ISSN:1784-3286
DOI:10.1080/17843286.1992.11718213
出版商:Taylor&Francis
年代:1992
数据来源: Taylor
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2. |
A Randomized Placebo Controlled Trial On The Effects Of Simvastatin, A Hmg-Coa Reductase Inhibitor, On Blood Lipids And Fibrinolytic Parameters |
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Acta Clinica Belgica,
Volume 47,
Issue 2,
1992,
Page 82-89
JacobsH.,
Van de WerfF.,
LesaffreE.,
De GeestH.,
CollenD.,
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摘要:
SummaryCoronary artery disease is frequently associated with disturbed blood lipids and with a deficient blood fibrinolytic capacity. In order to investigate a possible link between hypercholesterolemia and hypofibrino-lysis, we have investigated the effect of simvastatin, a HMG-CoA reductase inhibitor, on blood lipids and fibrinolytic parameters in a double blind, randomized, placebo controlled study design. Twenty-four male patients, aged between 42 and 65 years, with angiographically confirmed coronary artery disease, were selected from a series of 731 consecutive patients on the basis of a fasting serum cholesterol level of more than 250 mg/dl and a plasma PAI-I level of more than 60 ng/ml. Patients were randomly assigned to 20 mg of simvastatin daily (Group I), or placebo (Group II), for four weeks, followed by doubling of the dose for another four weeks. Blood samples were obtained at baseline and at 4 and 8 weeks. Groups I and II did not differsignificantly at baseline. As expected, simvastatin produced a significant reduction in serum levels of total cholesterol (33±12 and 36±12 percent, mean±SD, after 4 and 8 weeks respectively, p<0.001 vs baseline), LDL-cholesterol (36±5 and 43±6 percent respectively, p<0.00 I vs base line) and a polipoprote in-8 (20±29 and 23±30 percent respectively, p<0.05 vs) baseline), whereas these parameters did not change significantly in the place bo group. The PAI-I levels decreased to a compara bleex tent in both groups (54±34 and 51±3 1 percent after 4 and 8 weeks repectively in the sim vas tatin group and 58±29 and 37±38 percent in the place to group p<0.0 I vs baseline), whereas t-PA decreased be tween 15 and 20 percent in both groups. These findings suggest the at there is no causal relationship between hypercholesterolemi a and its associated changes in blood lipids on the one hand , and) decreased blood fibrinolytic capacity on the other hand. The comp arable decreases of PAI-I levels in both groups are probably secundary to improved dietary control during the study peri od. although no significant changes in plasma insulin level or body weight were observed.
ISSN:1784-3286
DOI:10.1080/17843286.1992.11718214
出版商:Taylor&Francis
年代:1992
数据来源: Taylor
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3. |
Le Syndrome Hypereosinophilique (She) A Propos De Deux Cas Et Revue De La Litterature. |
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Acta Clinica Belgica,
Volume 47,
Issue 2,
1992,
Page 90-97
StraetmansN.,
FerrantA.,
MartiatP.,
SokalG.,
MichauxJ.L.,
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摘要:
SummaryIdiopathic hypereosinophilic syndrome is characterized by prolonged eosinophiliaof undetected cause and multiple organ system involvement (lung, kidney, nervous system, skin,…). Nevertheless, the prognosis has been correlated with heart involvement, which usually results in a restrictive cardiomyopathy with apical obliteration by fibrosis, mural thrombi and mitral and tricuspid regurgitation.This disease has a wide range of severity: some patients suffer from a real myeloproliferative syndrome and may develop blastic transformation while others present only skin involvement or are asymptomatic.Corticosteroids and hydroxyurea are both effective treatments. Interferon a seems to be active for the myeloproliferative form of the disease.Cytotoxic activity of activated eosinophil granular proteins may play an important role in tissue damage. The cause of eosinophilic proliferation (primitive malignant proliferation or resulting from a T lymphocyte stimulus) and activation remains uncertain.
ISSN:1784-3286
DOI:10.1080/17843286.1992.11718215
出版商:Taylor&Francis
年代:1992
数据来源: Taylor
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4. |
Diagnostic Strategy For Fever Of Unknown Origin In The Ultrasonography And Computed Tomography Era |
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Acta Clinica Belgica,
Volume 47,
Issue 2,
1992,
Page 100-116
KnockaertD.C.,
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摘要:
SummaryFever of unknown origin strictly defined by Petersdorf in 1961 may be caused by a whole array of conditions. A rational approach should be based upon the relative frequencies of the different causes and their importance for the health and life of the patient. Risks, discomfort and, to a limited degree, costs must be taken into consideration.The investigation protocol we propose takes into account all these factors and is mainly based upon an extensive literature survey and our personal experience with a series of 199 patients studied in the 1980 s.
ISSN:1784-3286
DOI:10.1080/17843286.1992.11718216
出版商:Taylor&Francis
年代:1992
数据来源: Taylor
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5. |
HIV-Related Thrombocytopenia |
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Acta Clinica Belgica,
Volume 47,
Issue 2,
1992,
Page 117-123
BlockmansD.,
VermylenJ.,
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摘要:
HIV-related chronic ITP is caused by an accelerated platelet destruction due to adsorption of circulating immune complexes and to specific anti-platelet antibodies, but perhaps also by a defective thrombo-poiesis resulting from invasion of the megakaryocytes by the retrovirus. Treatment is needed when platelet numbers drop beneath 20.10’/Lor when severe bleeding symptoms occur. Steroids, commercially available immunoglobulins for IV use, AZT and anti-Rh immunoglobulins can be administered, although relapses are frequent after withdrawal of the drugs. Recurrences after splenectomy are far less common, but the progression towards AIDS might be accelerated.
ISSN:1784-3286
DOI:10.1080/17843286.1992.11718217
出版商:Taylor&Francis
年代:1992
数据来源: Taylor
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6. |
Intrathoracic Infections With Bacteraemia Due toEikenella CorrodensAs A Complication Of Peritonsillar Abscesses: Report Of A Case and Review of The Literature. |
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Acta Clinica Belgica,
Volume 47,
Issue 2,
1992,
Page 124-128
ZgheibA.,
ElAllafD.,
DemontyJ.,
Rorive*.G.,
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摘要:
SummaryA 52-year-old man, without previous disease, presented with dysphagia, dyspnoea, high fever and sore throat after peritonsillar abscesses drainage. Physical and complementary examinations were consistent with pericarditis, mediastinitis, pneumonia and pleuritis. Blood cultures grewEikenella corrodensresistant to clindamycin and amikacin. We emphasize the pathogenic potential ofEikenella corrodens.Tothe best of our knowledge, this is the first reported case of this organism as a pathogen in intrathoracic infections after peritonsillar abscesses drainage.
ISSN:1784-3286
DOI:10.1080/17843286.1992.11718218
出版商:Taylor&Francis
年代:1992
数据来源: Taylor
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7. |
Persistent Diarrhoea andBlastocysts Hominis |
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Acta Clinica Belgica,
Volume 47,
Issue 2,
1992,
Page 129-130
LambertM.,
GigiJ.,
BughinC.,
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ISSN:1784-3286
DOI:10.1080/17843286.1992.11718219
出版商:Taylor&Francis
年代:1992
数据来源: Taylor
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8. |
Resistance To Amoxicillin/Clavulanate inEscherichia Coli |
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Acta Clinica Belgica,
Volume 47,
Issue 2,
1992,
Page 131-131
LontieM.,
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ISSN:1784-3286
DOI:10.1080/17843286.1992.11718220
出版商:Taylor&Francis
年代:1992
数据来源: Taylor
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9. |
Abstracts of the meeting of the Belgian Society of Internal Medicine (7 February 1992) |
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Acta Clinica Belgica,
Volume 47,
Issue 2,
1992,
Page 132-138
WettendorffP.,
El HaddadC.,
LeautaudP.,
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ISSN:1784-3286
DOI:10.1080/17843286.1992.11718221
出版商:Taylor&Francis
年代:1992
数据来源: Taylor
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10. |
Abstracts of the meeting of the Belgian Committee of Hypertension (14 March 1992) |
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Acta Clinica Belgica,
Volume 47,
Issue 2,
1992,
Page 139-148
DelangheJ.,
DuprezD.,
DeBuyzereM.,
BergezB.,
CallensB.,
ClementD.L.,
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ISSN:1784-3286
DOI:10.1080/17843286.1992.11718222
出版商:Taylor&Francis
年代:1992
数据来源: Taylor
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