摘要:

SummaryPatients who have undergone a surgical procedure without infection show an important increase of the alcaline phosphatase in serum. The same thing was noticed after severe hemorrhage, also after extensive burns and in two cases with ischemic gangrene of the lower limb.In dogs such a hyperphosphatasemia was produced by a rapid and important bleeding; reinjection of the blood into the peritoneal cavity increased the phenomenon.The hyperphosphatasemia is not immediate; it is not linked to the hyperglycemia that follows the traumatic shock, no more to the hyperthermia because it was observed in cases without temperature such as severe bleeding or ischemic gangrene of the limbs.Work is performed to elucidate the origin of the hyperphosphatasemia observed in surgical conditions.

ISSN:1784-3286    

DOI:10.1080/17843286.1950.11716569

出版商:Taylor&Francis    

年代:1950

数据来源: Taylor

摘要:

SummaryAn electrophotometric method is described which gives records of the volumetric variation of the pulse with great accuracy. The method has been used to study the vasodilatator effect of some drugs.Intravenous administration of nicotinic acid or of 2 benzyl 4-5 imidazoline chloride definitely increases the volumetric variation of the pulse. This increase is of short duration, but is noticeable in several parts of the body.

ISSN:1784-3286    

DOI:10.1080/17843286.1950.11716570

出版商:Taylor&Francis    

年代:1950

数据来源: Taylor

摘要:

SummaryHyperœstrogenism is generally recognised as the cause of metropathia hæmorrhagia associated with hyperplastic endometrium, a syndrom described many years ago by Schröder.However hyperœstrogenism does not always produce such well characterized symptoms. In some cases hyperœstrogenism remains in discussion when endometrial biopsy shows for instance a picture not corresponding to the period of the menstrual cycle at which the biopsy was taken. Il is the author’s opinion that such cases are frequently observed in a clinical characteristic type of women.In such type of hyperœstrogenism, complains are not limited to the genital sphere. General symptoms are met with : a slight enlargement of the thyroid gland is frequently noted with symptoms suggesting moderate Basedow disease ; congestive manifestations in the mammary glands with microkystic mastitis are observed as well as a tendency to hyperadrenalism with slight hirsutism.Such clinical signs suggest hyperactivity of several glands rather than pure hyperœstrogenism, perhaps also hyperpituitarism.

ISSN:1784-3286    

DOI:10.1080/17843286.1950.11716571

出版商:Taylor&Francis    

年代:1950

数据来源: Taylor

摘要:

SummaryAuthor emphasizes the importance of the bulged pulmonary artery for the diagnostic of some heart diseases.He shortly describes the different heart diseases which show this roentgenologic abnormality and notices their most pathognomonic symptoms. Some investigations as catheterisation of the heart cavities, angiocardiography, rebreathing test and ratio of oxygen utilization (Bing’s test) are specially valuable for diagnosis.At last, a practical classification of the heart diseases with bulged pulmonary artery is proposed.

ISSN:1784-3286    

DOI:10.1080/17843286.1950.11716572

出版商:Taylor&Francis    

年代:1950

数据来源: Taylor

摘要:

SummaryEthyl ester of 4–4’dioxycoumarinyl acetic acid has on dicoumarol several advantages. His effects are more rapid and constant although easily reversible.A survey of the methods used to follow the effects of the drug is done.

ISSN:1784-3286    

DOI:10.1080/17843286.1950.11716573

出版商:Taylor&Francis    

年代:1950

数据来源: Taylor

摘要:

SummaryA child, three months old, showing bones defects of the skull associated with cutaneous lesions of a papulous type is studied. A biopsy of the skull tumors showed an eosinophilic granuloma.Later on the clinical picture was that of Letterer-Siwe’s disease : fever with hepatic and splenic enlargement, severe hypochromic anemia and extensive infiltration of the lungs with dyspnoea and cyanosis. The child died three months after the first symptoms appeared. Pathological study showed a reticular proliferation in the nodes, thymus, lunga, liver, spleen, lymphoid nodes of the bowel and skin.In the lymph nodes the picture was somewhat comparable to that of Besnier-Boeck’s disease. In the thymus the cells were frequently filled with lipoids, partly birefringent.This cass brings some support to the view that eosinophilic granuloma of the bones, Schüller-Christian’s and Letterer-Siwe’s diseases have a common basis. All three are characterised by a reticular proliferation. It seems that Schüller-Christian’s disease must be separated from the other diseases grouped as lipoidosis.The evolution of the disease here studied as well as the histological picture suggest an infectious origin, but no confirmation has been brought until now.The prognosis of eosinophilic granuloma is generally benign although in some rare cases general involvement leading to the Letterer-Siwe’s syndrom occurs. No therapy has been proposed in the generalized form.

ISSN:1784-3286    

DOI:10.1080/17843286.1950.11716574

出版商:Taylor&Francis    

年代:1950

数据来源: Taylor

摘要:

SummaryDescription, in a female of 50 years, of cutaneous hæmangioma of right half of neck, chest and abdomen, both shoulders, upper part of back, both buttocks and, less marked, of the limbs. Marked phlebectasia of left hind limb (metameric topography) and of bend of the right arm. Aspect of veinous stasis of right eyelid, conjunctiva and fundus; also, of right hemi-pharynx.Moderate hyperplasia of right half of the body, more particularly of right arm and face. Acromegalic aspect of both hands and feet. All malformations seem congenital.Some pigmentated nœvi on the both legs (under the knees). On X-ray exami nation, bones of hands and fingers are hypertrophied but show some slight appearances of osteo-articular malformations. Hypotrophy of right cranial and facial bones. No tumor of hypophysis.Etiology and pathogenesis of case seem complex. Interference of nervous factors is proved by metameric topography of cutaneous angioma on neck, breast and abdomen, and of phlebectasia on left hind limb. Nervous pathogenesis is emphasized by the fact that patient is feeble minded and that her sole son is imbecile.Hormonal factors are also implied as shown by acromegalic aspect of hands and feet, and precocious menopause (39 years).

ISSN:1784-3286    

DOI:10.1080/17843286.1950.11716575

出版商:Taylor&Francis    

年代:1950

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1950.11716577

出版商:Taylor&Francis    

年代:1950

数据来源: Taylor