ISSN:1784-3286    

DOI:10.1080/17843286.1976.11717075

出版商:Taylor&Francis    

年代:1976

数据来源: Taylor

摘要:

SummaryThe existence of different stem cell populations has been reported. Different sub-populations of committed-secondary stem cells arise from a less differentiated pluripotent-primary-stem cell. Primary stem cells have an extensive capacity. for self-renewal. The secondary stem cells have a limited self-renewal capacity and are committed tot the formation of red cells, granulocytes and monocytes, or platelets. Hormonal substancef are needed for their proliferation and differentiation. The circulating blood cells and functional demands are of major importance in the , different feedback systems which govern haemoPoiesis.

ISSN:1784-3286    

DOI:10.1080/17843286.1976.11717076

出版商:Taylor&Francis    

年代:1976

数据来源: Taylor

摘要:

SummaryThe development of new methodology has resulted in a more profound knowledge of the kinetic and physical properties of the haemopoietic stem cells. Primary and secondary stem cells belong to different cell populations. Only a small fraction of the CFU-S are in cell cycle. Most erythropoietin-sensitive stem cells and about 50% of the CFU-C are synthesizing DNA at any one time. Little is known about the proliferate state of the megakaryocyte precursors. The regulating factors which govern the transi-tion of stem cells from the primary stem cell compartment into one of the secondary stem cell populations are not well known. Different factors are involved : population size control, genetic factors and the inductive micro-environ-ment. Morphological characterisation and identification have shown that primary stem cells are closely related to small lymphoid cells. Further data indicate that the haemopoietic and im-munopoietic stem cells are derived from a common ancester cell.

ISSN:1784-3286    

DOI:10.1080/17843286.1976.11717077

出版商:Taylor&Francis    

年代:1976

数据来源: Taylor

摘要:

SummaryMitral and pulmonary staphylococcal endocar-ditis in a heroin addict.Endocarditis and other infectious diseases are a most frequent complication of heroin addiction, second only to overdosage. A lethal case of staphylococcus aureus endocarditis in a heroin addict patient is reported. Findings included involvement of mitral and pulmonary valves, pericarditis, peripheral and pulmonary septic emboli, and renal failure. Pathological examination de-monstrated disseminated phagocytised talc particles.Perusal of previously reported cases pointed out several characteristics of heroin addict endocarditis. Tricuspidian staphylococcal endocarditis is the rule whereas pulmonary valve involvement is exceptional. High bacterial activity is assumed to be the cause of the severe and rapid evolution which is commonly observed. Heart murmurs are generally of poor diagnostic value. Most frequency associated complications include pulmonary emboli with secondary abscess, parenteral injection of talc or cotton particles, and serum hepatitis (HAA).Increased concentration of immunoglobulins (IgM) is frequently demonstrated.Renal complications in heroin addict patients (glomerulonephritis) are associated with antigen-antibody deposits (unknown antigen) upon the glomerular basement membrane, as described in bacterial endocarditis and particularly in staphylococcal endocarditis.

ISSN:1784-3286    

DOI:10.1080/17843286.1976.11717078

出版商:Taylor&Francis    

年代:1976

数据来源: Taylor

摘要:

SummaryThe susceptibility of 143 non-pigmented strains of 5 marcescens to several aminoglycosides was determined by an agar dilution technique. Only 31% of the strains were susceptible to gentami cin (4μg/ml) and 35% to kanamycin (8μg/ml) However 96.5% remained susceptible to tobramycin (4μg/ml) and 100% to amikacin 8μg/ ml). Strains collected in the immediate surrounding of infected patients showed exactly the same susceptibility pattern

ISSN:1784-3286    

DOI:10.1080/17843286.1976.11717079

出版商:Taylor&Francis    

年代:1976

数据来源: Taylor

摘要:

SummaryThe clinical and biological aspects of one case of hereditary angioneurotic oedema are described. Current pathophysiological mechanisms are reviewed. Clinical recovery was complete after metandienone therapy.

ISSN:1784-3286    

DOI:10.1080/17843286.1976.11717080

出版商:Taylor&Francis    

年代:1976

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1976.11717081

出版商:Taylor&Francis    

年代:1976

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1976.11717082

出版商:Taylor&Francis    

年代:1976

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1976.11717083

出版商:Taylor&Francis    

年代:1976

数据来源: Taylor