ISSN:1784-3286    

DOI:10.1080/17843286.1995.11718412

出版商:Taylor&Francis    

年代:1995

数据来源: Taylor

摘要:

SummaryTuberculosis is a world-wide persistent problem. Treatment is usually successful when the bacteria are drug-susceptible and patient compliance ensured. We report our results of treatment of high-risk patients without social security coverage in Brussels. Double and triple fixed antituberculous agents in combined tablets were used. Cure was obtained without drug toxicity in all patients who completed therapy. Only 19, 5% of patients failed to complete therapy.

ISSN:1784-3286    

DOI:10.1080/17843286.1995.11718413

出版商:Taylor&Francis    

年代:1995

数据来源: Taylor

摘要:

SummaryHantavirus (HTV) is a recently discovered“hemorrhagic fever virus”belonging to the Bunyaviridae family, which is spread throughout the world by wild rodents and/or laboratory rats. During an epidemic in the Belgian-French Ardennes in 1993, more than 200 acute cases were recorded of the milder European form of HTV-illness, otherwise known as Nephropa-thia epidemica (NE). This variant may be recognized by the sudden onset of fever, acute renal failure, thrombocytopenia and sometimes by ophthalmologic complications. The symptomatology is rather aspecific and diagnosis can only be confirmed by serologic tests, of which the best option nowadays seems to be: screening by IgG EIA, followed by IgM confirmation with a (i-capture EIA test. Some of the tests described allow an evaluation of the causative serotype or even the moment of infection.Next to the“classic”serologic assays for detection of specific viral antibodies, we describe briefly our own experience with newer tests such as“high density particle agglutination”and“line immuno assay”. Polymerase chain reaction for viral RNA genome typing and immunohistochemical colouring of the viral antigen in tissues seem to offer promising alternatives for the immediate future.

ISSN:1784-3286    

DOI:10.1080/17843286.1995.11718414

出版商:Taylor&Francis    

年代:1995

数据来源: Taylor

摘要:

SummaryChyle is a fluid rich in triglycerides and is characterized by the presence of chylomicrons. Chylous effusions are unusual complications of malignant neoplasms, usually lymphomas. The combination of chyloperitoneum and chylothorax is very rare. When abdominal lymphatics are obstructed, chylous ascites results and eventually leads to a chylothorax. We present the case of a 68-year-old woman with a chy-loperitoneum and a right-sided chylothorax due to an underlying malignant B-cell lymphoma. After thoracocentesis and replacement therapy with medium chain triglycerides, she was treated with a combination of cyclophosphamide, vincristin and prednisone. This has resulted in a regression of the chylous effusions. A short review of the literature describes causes, diagnosis and therapy of chylous effusions.

ISSN:1784-3286    

DOI:10.1080/17843286.1995.11718415

出版商:Taylor&Francis    

年代:1995

数据来源: Taylor

摘要:

SummaryCutaneous metastases presenting as the first sign of cancer are rare. We present two cases of such metastases, one being a so-called sister Mary Joseph’s nodule. The histologic findings revealed adenocarcinomas with features suggesting a primary gastrointestinal neoplasm.

ISSN:1784-3286    

DOI:10.1080/17843286.1995.11718416

出版商:Taylor&Francis    

年代:1995

数据来源: Taylor

摘要:

SummaryWe report the case of a middle-aged woman suffering from a relapsing sterile inflammatory arthritis preceded by a streptococcal infection. This observation suggests that streptococcal infection may need to be included in the list of infections known to precipitate reactive arthritis. The clinical presentation of poststreptococcal arthritis in adulthood and its relationship to acute rheumatic fever is discussed.

ISSN:1784-3286    

DOI:10.1080/17843286.1995.11718417

出版商:Taylor&Francis    

年代:1995

数据来源: Taylor

摘要:

SummaryThe cases of two elderly women treated for temporal hemianopsia due to a large pituitary mass with suprasellar extension are presented. In both cases, the clinical picture, without diabetes insipidus and cranial nerve paralysis, as well the neuroimaging and endocrinological investigation showing hypopituitarism, were suggestive of a non-secreting pituitary adenoma. In the first patient malignant tissue was unexpectedly encountered during transsphenoidal surgery. Anato-mopathological investigation confirmed the presence of a metastasis of a breast carcinoma for which she had been treated 17 years earlier. In the second patient, a preoperative chest X-ray before transsphenoidal surgery revealed an asymptomatic bronchial tumour. Subsequently a squamous cell carcinoma with a metastasis in the pituitary was confirmed. These two cases illustrate the fact that a pituitary metastasis can closely mimic a pituitary adenoma. Even in the absence of suggestive symptoms such as diabetes insipidus and/or cranial nerve paralysis the possibility of metastatic disease in the differential diagnosis of a pituitary mass should always be considered.

ISSN:1784-3286    

DOI:10.1080/17843286.1995.11718418

出版商:Taylor&Francis    

年代:1995

数据来源: Taylor

摘要:

SummaryA 53-year-old woman suffered six episodes ofClostridium difficile-pscudomcmbranous colitis. The serological follow-up demonstrated the absence of a rise in IgG and IgA to toxin A. Human pooled gamma globulin was administered during the fifth relapse and raised IgG levels to toxin A. Normal stools reappeared a week later. The role of the antibodies to toxin A and gamma globulin inC. difficilecolitis are discussed.

ISSN:1784-3286    

DOI:10.1080/17843286.1995.11718419

出版商:Taylor&Francis    

年代:1995

数据来源: Taylor

摘要:

A new international reference preparation for proteins in human serum has been recently proposed in Europe from the Community Bureau of Reference (Brussels) under the name CRM 470 (Certified Reference Material) and in the United States from the College of American Pathologists under the name RPPHS (Reference Preparation for Proteins in Human Serum).This serum based material offers the opportunity to the laboratories to standardize their serum protein concentrations, and to improve dramatically the transferability of the results from studies to the local working conditions. The International Federation of Clinical Chemistry strongly recommends the use of this preparation by all laboratories. The Belgian Institute of Hygiene and Epidemiology expects an improvement in the agreement of the results of the three proteins (IgA, IgG, CRP) included in its external quality control of the clinical laboratories. These proteins were omitted from the controls of the second semester of 1994, but would reappear in early 1995, after the conversion of the laboratories to the new protein calibrators. Of course, this implies the assigment of new reference ranges for most of the serum proteins, some of them being significantly modified (a 1-antitrypsin, haptoglobin, transferrin, C3, IgM). The clinical chemists must inform the physicians of these changes.

ISSN:1784-3286    

DOI:10.1080/17843286.1995.11718420

出版商:Taylor&Francis    

年代:1995

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1995.11718421

出版商:Taylor&Francis    

年代:1995

数据来源: Taylor