摘要:

SummaryIndium 113mis a radioisotope with a half-life of 1.7 hour and a monoenergetic gamma radiation of 393 KeV.It may be prepared by elution of a Sn113generator. Several molecules labeled with Indium may be quickly and easily obtained.The physical and chemical properties of Indium are described along with a study of the isotope generator.The various clinical applications of Indium 113mare discussed and illustrated. Indium stablilized by gelatine may be used for determination of intravascular space, measurement of cardiac output and scintigraphy of the heart and placenta.Indium chelated by DTPA is used in nephrography, renal and cerebral scintigraphy and measurement of glomerular filtration rate. Colloidal Indium is used in hepatic and splenic scintigraphy. Finally, scintigrams of the lungs may be obtained by means of Indium labeled macroaggregates of iron hydroxyde.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716756

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummaryAfter having described the technique of lymphography, the author details the normal radiological anatomy of the retroperitoneal lymph system.In lymphcedema the presence of specific lymphangiography patterns allow the differentiation between primary hypoplasia or malformation of the lymph vessels from secondary fibr osis or stasisLymphography is of particular interest in the identification of tumors of the lymph vessels and in the detection of the origin of chylous effusions.In the second part, the pathology of the lymph nodes is studied. The«typical>lymphographie features of metastasis and of several classes of lymphomas arc illustrated. Often however it appears to be impossible to differentiate these pathological processes since unspecific changes are likely to occur. Moreover the radiological aspect of complete lymph node destruction is common to the late evolution-stage of all of these diseases.Thus lymphography permits the study of a region of the human anatomy which is very difficult to examine; in well selected cases important information can be gained from this simple and safe investigation.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716757

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummaryA sensitivity study of 288 M.tuberculosis strains, isolated in the area of Brussels during the past year (May 1969 to May 1970), to specific antibiotics, lead to the following considerations :1) a large number of strains remained sensitive to streptomycin (85 %), to PAS (95 %), to INH (84 %) as well as to all the tuberculostatic drugs applied (75 %).2) in most cases the new patients had been sheltering sensitive strains; almost all the resistant strains originated, when the previous case history could be established, from well-known tuberculous patients who had already been submitted to chemotherapy.3) among the 29 multiple resistant strains, 3 (10 %) were resistant to rifam-picin; on the contrary, no resistance has been detected to ethambutol.4) in newly detected patients, the choice of an anti-tuberculous therapy, previously to the results of the antibiogram, presently remains largely open and the medication has to be established in function of clinical criteria as well as criteria concerning therapeutical efficacy.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716758

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummaryThe action of the antihypertensive agent, debrisoquin (Declinax®) is, both in pharmacological studies on animals and in its clinical use, similar to guanethidine (Ismelin®). They have the following characteristics in common : they inhibit the adrenergic neuromuscular transmission; they provoke a transient release of norepinefrine and a short lasting blood pressure rise after the first intravenous injection; their blood pressure lowering effect is more pronounced in the standing than in the recumbent position, which frequently leads to orthostatic hypotension; in acute experiments the blood pressure decrease is due mainly to a decrease of the cardiac output, the changes in total peripherial resistance being variable; their blood pressure lowering effect is antagonised by imipramine (Tofranil®); their side-effects are similar in nature : orthostatic hypotension, diarrhoea, muscle weakness.Debrisoquin differs from guanethidine. The antihypertensive action of debrisoquin has a quicker onset and is shorter lasting : the drug should therefore be given at least three times a day and is considered by certain workers as more easy to handle; debrisoquin does not inhibit the uptake of norepinephrine from the extracellular fluid; debrisoquin does not lower the norepinephrine concentration in the heart or brain of the experimental animal; debrisoquin inhibits in vitro the mono-amino-oxydase of platelets, probably also in the neurones, but not in the wall of the duodenum. It is not definitely excluded that the ingestion of certain cheeses or wines could provoke a hypertensive attack in debrisoquin treated patients.A controled clinical trial comparing debrisoquin to other inhibitors of the adrenergic neuromuscular transmission, such as guanethidine, or bethanidine is upto now not available; it is therefore not proven that debrisoquin is superior in the chronic antihypertensive treatment.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716759

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummaryThe speed of the bactericidal activity of penicillin G and ampicillin has been investigated onNeisseria meningitidis. Both these antibiotics are active at the same speed.The activity curves of penicillin G and ampicillin may be split up into segments. Following a short bacteriostatic phase the bactericidal activity is noted. The increase of the antibiotic concentration induces mainly shortening of the oarly bacteriostatic phase.As an important parameter for the choice of antibiotics to be applied in the therapy of mcningites, the performed study shows that both drugs are equivalent in this regard.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716760

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummarySince the first report in 1928 about 200 tumors with ectopic ACTH syndrome have been reported. From hormonal assays in serum and in tumor tissue of unse-lected cases with carcinoma it can be inferred that this paraneoplastic Cushings' syndrome could exist in about 10 % of visceral carcinomas; it seems therefore that many incomplete or asymptomatic cases are overlooked. A review of clinical and biological features shows that parameters for the diagnosis of ectopic ACTH production are unreliable and that, without a final proof with the demonstration of a ACTH-like substance in the tumor tissue, some cases cannot be distinguished from tumors with pituitary-dependent hypercortisolism.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716761

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummaryA case of chronic lymphocytic leukemia terminating as an acute leukemia is reported. This type of evolution is exceptional as indicated by a review of the pertinent literature. The significance of these cases is discussed. The diverse malignant maladies arriving in the course of the chronic lymphoid leukemia are also treated. Other types of malignancy coincidential to chronic lymphoid leukemia are also discussed.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716762

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

摘要:

SummaryNervous complications of haemophilia are reviewed. A case of type A haemophilia is reported, with bilateral involvement of the femoralis and femoralis cutaneus nerves, illustrated by an electromyographic study.

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716763

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1970.11716764

出版商:Taylor&Francis    

年代:1970

数据来源: Taylor