ISSN:1784-3286    

DOI:10.1080/22953337.1978.11718611

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

SummaryAlpha-l-antitrypsin (α1 AT) is a plasma protein with a protease enzyme inhibitory capacity; its synthesis is genetically determined. Some diseases are characterised by a low serum concentration ofα1 AT of abnormal biochemical structure. Such a deficiency may be associated in childhood with cirrhosis of the liver following neonatal hepatitis and in the adult with lung and liver disease.A case of an homozygousα1 AT deficiency in an adult with emphysema and cirrhosis associated with hacmochromatosis is presented.

ISSN:1784-3286    

DOI:10.1080/22953337.1978.11718612

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

SummaryCreatinine, calcium (Ca), phosphate, immuno-reactive parathyroid hormone (i PTH) and calcitonin (i CT) blood levels were measured before and after haemodialysis (HD) in 24 patients submitted to regular dialysis treatment, and in the days following successful renal transplantation (RT) in other patientsi PTH and i CT levels were elevated before HD; the rise of plasma Ca following HD was accompanied by a decrease in i PTH (P<0.001), whereas i CT was increased, though not significantly.The levels of i PTH and i CT, elevated before RT, returned to normal after RT, together with creatinine and P levels; a rejection after some days in 2 patients was followed by a rapid increase in i PTH and i CT levels. One patient who underwent subtotal parathyroidectomy 281 days after RT because of persistent hypercalcaemia and high i FTH levels is also presented.

ISSN:1784-3286    

DOI:10.1080/22953337.1978.11718613

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

SummaryA case of leukemia following the prologned use of a cytotoxic drug for a non malignant disease is reported. A 55 year old female presented with asthenia and severe anaemia. The blood smear showed immature myeloid cells and many erythroblasts. A diagnosis of crythroleukemia could be made by bone marrow biopsy. Ten years earlier this patient had been treated for scleromyxedema with D-L Melphalan. This treatment had been continued with interruptions for approximately eight years.The litterature on the occurence of acute leukemia after longstanding treatment with alkylating agents in malignant and non-malignant conditions is reviewed. The possible mechanisms of this type of leukomogenesis are discussed.

ISSN:1784-3286    

DOI:10.1080/22953337.1978.11718614

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

SummaryReport of two cases of echinococcosis of lung and liver and review of the literature.

ISSN:1784-3286    

DOI:10.1080/22953337.1978.11718615

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

SummaryAmpicillin-resistanlHaemophilus influenzaewere reported from several countries since 1973. Their prevalence appears to be low, and depending on the geographical location of the laboratory, varies from 0 tot 8 % in Belgium. Ampicillin-resistance in Haemophilus is caused by aβ-lactamase of the TEM-type, as frequently found in enteric bacteria. Two different plasmids coding forβ-lactamase production and sharing a common TnA sequence, were identified. Intraand intergeneric transfer of resistance by conjugation have been performed in vitro.Beta-lactamase producingNeisseria gonorrhoeaehave been isolated since 1976. Until now, their spread was usually limited in Europe and North America, but a high prevalence was found in South East Asia and West Africa. In Belgium only one strain, originating from the Ivory Coast, has been reported, but further importation of penicillin-resistant gonococci is probable. Two R-pIasmids with different molecular weight were found coding for TEM-type beta-lactamase production.The ability to produce beta-lactamase was transferred in vitro by conjugation to otherNeisseriaeandEscherichia coli.Several rapid methods for beta-lactamase detection inHaemophiliandNeisseriaehave been developed for use in the clinical laboratory.Implications for the clinical laboratory and the management of infections with these organisms are discussed.

ISSN:1784-3286    

DOI:10.1080/22953337.1978.11735735

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

SummaryThe authors report on an acute renal failure occuring in a 34-year old man clue to leptospira icterohaemorrhagiae. The diagnosis is evoked clinically: association of jaundice, acute renal failure, fever, elevated leucocytosis in a fisherman. The serological studies confirm the clinical suspicion. Hemodialysis was successful. Recent literature is reviewed. Pathogenesis—like in ethers tubular intertitial nephritis—is not convincingly established. Pathogenies mecanisms have been postulated for leptospirosis.

ISSN:1784-3286    

DOI:10.1080/22953337.1978.11718617

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

SummaryA 76-year-old man developed a circulating inhibitor against factor V after abdominal surgery, ampicillin and one unit of blood were given. Twelve days after the cholecystectomy a minor bleeding problem was observed. Coagulation screening test indicated the presence of the potent inhibitor. A concomittant antibody with antipcnicillin specificity was confirmed.

ISSN:1784-3286    

DOI:10.1080/22953337.1978.11718618

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

摘要:

SummaryThis ease report concerns a 24 year old male, who was followed for a severe aplastic anaemia and showed enlargement of the left cervical lymphnodes. The histological type was Morbus Iiodgkin of the lymphocyte predominant type. At repeated examinations, Hodgkin cells were not found in the bone marrow aspirates. The patient never received any treatment. There was no apparent pre-existing immune deficiency. Lymphnodes were present for almost 2 years. The aplastic anaemia probably is due to exposure to myelotoxic chemicals. The patient died from a cerebral haemorrhage. At the postmortem examination, Hodgkin’s disease was limited to the left supraclavicular region.

ISSN:1784-3286    

DOI:10.1080/22953337.1978.11718619

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/22953337.1978.11718620

出版商:Taylor&Francis    

年代:1978

数据来源: Taylor