ISSN:1784-3286    

DOI:10.1080/22953337.19811.11718832

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

摘要:

SummaryThis paper describes two Belgian families in which congenital plasma antithrombin III deficiency was found. Both propositi presented with recurrent iliac vein thrombosis. These patients strikingly illustrate known features of antithrombin III deficiency: the occurrence of thrombosis in association with the intake of oestrogen or with pregnancy and delivery; the relative resistance to the anticoagulant effect of heparin; the rebound hypercoagulability following interruption of heparin administration, due to a more pronounced decrease of the antithrombin III level. The relevant literature is reviewed.

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718833

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

摘要:

SummaryThe acute effects of the angiotensin converting enzyme inhibitor captopril were studied in patients With essential (n = 9) or renovascular hypertension (n = 10) 75 min after ingestion of 25 mg of the drug, and 13 patients were restudied after 2 rnonths when on 150–600 mg/day. Captopril acutely decreased the arterial plasma angiotensin II (PA II) level by 49 % (P<0.001) with no further change during chronic treatment. Plasma aldosterone concentration dropped, while plasma renin activity and plasma angiotensin I levels rose during acute and chronic treatment. Mean brachial artery Pressure was acutely reduced by 16.4 mm Hg (P<0.001) while the chronic reduction was significantly greater by 9.2 mm Hg (P<0.001). A slight increase of heart rate of 3 beats/min (P<0.005) \vas observed in the acute but not in the chronic study.When compared with essential hypertension, patients with renovascular hypertension had a higher Control PRA level and a greater acute and chronic fall of blood pressure during captopril (P<0.05 for all), but the overlap was considerable. However, post-captopril plasma levels of angiotensin I Were highly significantly different between both•orms of hypertension and correcdy classified 9.5 % of the patients; minimal misclassification (5.3 %) was achieved by combining post-captopril angiotensin I with pre-captopril plasma angiotensin II levels.The data indicate that the hypotensive effect of Captopril is at least partly related to the changes of Arterial PA 11. The response of blood pressure to captopril does not allow a clear-cut distinction between essential and renovascular hypertension, but the components of the renin angiotensin system are more sensitive.

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718834

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

摘要:

SummaryTwenty patients (males) with pulmonary surinfection on bronchitis or silicosis are included in this Prospective and controlled trial. Ten patients paired for age, weight and serum creatinine receive either Gentamicin or Tobramycin at similar maintenance dosage during ten consecutive days. The increase of serum creatinine after ten days of treatment is respectively of 12.4±6.2μmole/1 (SD) Under Tobramycin and 44.2±37.1βmole/I Under Gentamicin (p<0.05). Urinary excretion of two tubular enzymes: N-acetyl-β-D-glucosaminidase and Alanine Amino Peptidase increases significantly and correlatedly (py a proximal tubular cell dysfunction.

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718835

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

摘要:

SummaryThe authors summarize their experience after more than 2000 determinations of intrathyroidal iodine (ITI) by means of the X-Ray fluorescence methode (XRF) and review the literature. This method explores the storage function of the thyroid, the so-called iodine pool with slow turnover rate, function that has hitherto been neglected because of lack of easily available means. The procedure is inocuous and the detector can readily be mounted on a conventionnal rectilinear scanner.The pattern of distribution of stable iodine within the gland and its qualifications have contributed to a better understanding of various thyroid disorders. Aside from its possibilities as far as the study of thyroid physiopathology is concerned, the method deserves its place in a routine clinical laboratory. Important information can be obtained, useful for diagnosis, treatment and prognosis in many instances, especially in hyperthyroidism and autoimmune thyroiditis. Altough it will not replace a radionuclide scan in most cases, it can serve as a substitute in those circumstances in which a radionuclide scan is not warranted or impossible to perform

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718836

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

摘要:

SummaryThree cases of giant cell arteritis and/or polymyalgia rheumatica are reported.They belong to the broad spectrum of clinical expression known to these diseases.Next, the nosological aspects are discussed about giant cell arteritis, polymyalgia rheumatica and Takayasu disease.The need for an early diagnosis leading to a correct treatment is then stressed.

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718837

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718838

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718839

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718840

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor