摘要:

The physical and chemical properties of thiophosgene with special reference to its use in organic syntheses are reviewed. Thiophosgene is best prepared by reductive dechlorination of trichloromethane-sulfenyl chloride. Besides its use in classical preparations of isothiocyanates, thioureas, thiocarbamates, and thiocarbonates, it has been extensively used to synthesize a wide variety of thioxo substituted heterocycles of pharmaceutical importance by cyclisation of amines, phenols, alcohols, and thiols. Thiophosgene is also used to prepare various inorganic complexes and in the conversion of phenols, thioureas, and thioamides to thiophenols, ureas, and amides, respectively. Reaction of thiophosgene with dienes and alkenes gives bridged compounds and different reactive synthons. The review also discusses the chemistry of the thiophosgene dimer.

ISSN:0196-1772    

DOI:10.1080/01961772.1986.10878146

出版商:Taylor & Francis    

年代:1986

数据来源: Taylor

ISSN:0196-1772    

DOI:10.1080/01961772.1986.10878147

出版商:Taylor & Francis    

年代:1986

数据来源: Taylor

ISSN:0196-1772    

DOI:10.1080/01961772.1986.10878148

出版商:Taylor & Francis    

年代:1986

数据来源: Taylor

ISSN:0196-1772    

DOI:10.1080/01961772.1986.10878149

出版商:Taylor & Francis    

年代:1986

数据来源: Taylor