|
11. |
Kinetic studies of lipoprotein metabolism in the metabolic syndrome including effects of nutritional interventions |
|
Current Opinion in Lipidology,
Volume 14,
Issue 1,
2003,
Page 61-68
P. Barrett,
Gerald Watts,
Preview
|
PDF (99KB)
|
|
摘要:
Nutritional interventions may favourably regulate dyslipoproteinemia and, hence, decrease cardiovascular disease risk. Lipoprotein kinetic studies afford a powerful approach to understanding and defining the mechanisms by which such interventions modulate lipoprotein metabolism. Stable isotope tracers and compartment models are now commonly employed for such studies.We review the recent application of tracer methodologies to the study of dyslipoproteinemia in the metabolic syndrome. We also focus on the effects of nutritional intervention studies that have addressed the effects of weight loss, n-3 fatty acids, plant sterols and alcohol on very low density lipoprotein, LDL and HDL metabolism. The potential for statin treatment as an adjunct to dietary modification is also discussed. New tracer methodologies are discussed, specifically those referring to reverse cholesterol transport.The nutritional interventions discussed in this review are readily transferable into clinical preventive practice. The potential benefits to be gained by weight loss and fish oil supplementation in the metabolic syndrome extend beyond their specific and positive effects on lipoprotein metabolism. Furthermore, recent developments in tracer methodologies afford new tools for probing the in-vivo pathways of lipoprotein metabolism in future studies.
ISSN:0957-9672
出版商:OVID
年代:2003
数据来源: OVID
|
12. |
Current World Literature |
|
Current Opinion in Lipidology,
Volume 14,
Issue 1,
2003,
Page 69-91
Preview
|
PDF (312KB)
|
|
ISSN:0957-9672
出版商:OVID
年代:2003
数据来源: OVID
|
13. |
Nutrition and metabolism |
|
Current Opinion in Lipidology,
Volume 14,
Issue 1,
2003,
Page 95-97
David,
Preview
|
PDF (44KB)
|
|
ISSN:0957-9672
出版商:OVID
年代:2003
数据来源: OVID
|
14. |
Genetics and molecular biology |
|
Current Opinion in Lipidology,
Volume 14,
Issue 1,
2003,
Page 99-101
Delia,
Recalde Mario,
Preview
|
PDF (48KB)
|
|
ISSN:0957-9672
出版商:OVID
年代:2003
数据来源: OVID
|
15. |
Lipid metabolism |
|
Current Opinion in Lipidology,
Volume 14,
Issue 1,
2003,
Page 103-106
Gary,
Preview
|
PDF (56KB)
|
|
ISSN:0957-9672
出版商:OVID
年代:2003
数据来源: OVID
|
16. |
Atherosclerosis: cell biology and lipoproteins |
|
Current Opinion in Lipidology,
Volume 14,
Issue 1,
2003,
Page 107-109
Peter,
Preview
|
PDF (44KB)
|
|
ISSN:0957-9672
出版商:OVID
年代:2003
数据来源: OVID
|
17. |
Therapy and clinical trials |
|
Current Opinion in Lipidology,
Volume 14,
Issue 1,
2003,
Page 111-113
Robert,
Preview
|
PDF (51KB)
|
|
ISSN:0957-9672
出版商:OVID
年代:2003
数据来源: OVID
|
|