ISSN:0273-8481    

出版商:OVID    

年代:1982

数据来源: OVID

ISSN:0273-8481    

出版商:OVID    

年代:1982

数据来源: OVID

ISSN:0273-8481    

出版商:OVID    

年代:1982

数据来源: OVID

摘要:

The beneficial effects of Aloe vera extract have been examined experimentally. In order to ascertain the distribution of the chemical constituents present in Aloe vera that may exhibit these beneficial effects, a complete chemical analysis was first performed. Inorganic substances (eg, sodium, potassium, chloride, calcium, and inorganic phosphorus) along with organic compounds (eg, glucose, protein, cholesterol, triglycerides, and salicylic acid) were found to be present. Trace metal analysis revealed that magnesium and zinc were also present. The bactericidal effects of the extract were also examined. Concentrations as low as 60% were found to be bactericidal against nine of the 12 species of organisms tested. These were Citrobacter sp., Serratia marcescens, Enterobacter cloacae, Klebsiella pneumoniae, Pseudomonas aeruginosa. Staphylococcus aureus, Streptococcus pyogenes. Streptococcus agalactiae, and Candida albicans. The remaining three species, Escherichia coli, Streptococcus faecalis, and Bacillus subtilis, all exhibited some resistance to the 60% concentration. However, all of these were susceptible to concentrations of 80% and 90%. A cream base containing 70% o/Aloe vera extract was found to be most effective in preserving the dermal microcirculation after thermal injury. This compound was demonstrated to inhibit some of the products of arachidonic acid metabolism such as thromboxane B, and to limit the production of prostaglandin F/x, thus preventing progressive dermal ischemia. These experimental data clearly show that the effects elicited by the Aloe vera extract are truly beneficial in a burn wound

ISSN:0273-8481    

出版商:OVID    

年代:1982

数据来源: OVID

摘要:

This study was designed to evaluate the potential beneficial effects of Hydron. a synthetic hum dressing, on scar contracture and wound healing following deep partial-thickness burns. Standard deep partial-thickness burn injuries were produced by an aluminum template on both sides of guinea pigs' backs. The rates of wound healing and scar contracture were measured at weekly intervals from the third to the eighth week. Hydron-treated wounds had significantly less contracture (26.6 ± 2.2% reduction in initial burn area) compared to wounds treated by exposure (72.3 ± 1.4%), silver sulfadiazine cream (Silvadene) (61.9 ± 2.4%), or bandage alone (56.7 ± 2.9%). Hydron-treated wounds also had faster wound healing (84.9 ± 2.1%c) than did wounds treated by exposure (57.5 ± 4.2%)). silver sulfadiazine (49.1 ± 4.4%c), or bandage alone (47.2 ± 5.8%); cosmetic appearance and hair growth were also superior in the Hydron-treated groups. Leaving Hydron dressing on the wounds for at least 3 weeks obtained the maximum benefit, perhaps by prevention of water vapor loss from the wound.

ISSN:0273-8481    

出版商:OVID    

年代:1982

数据来源: OVID

摘要:

This study investigates the usefulness of the quantitative gram stain procedure for predicting the results of human burn wound biopsy quantitative cultures. Quantitative gram stains and quantitative cultures were performed in parallel on I12 burn wound biopsy segments. Correlation of results predicted by the quantitative gram stain and those found on quantitative culture was poor as indicated by correlation coefficients of 0.68 for gram-positive cocci. 0.56 for gram-negative bacilli, and 0.55 for all microorganisms combined. Error rates in predicting a yield of >105cfu/gm (colony-forming units per gram) on quantitative culture were determined for the use of breakpoints (stained microorganisms per slide preparation) as determined respectively by regression analysis of data from the present study (I.I X 105), by a theoretical mathematical model (2 X I03), and one micro-organism per slide preparation as recommended previously by other investigators. Error rates for positive interpretations by these breakpoints, respectively, approximated 4%, 15%, and 26%. Error rates for negative interpretations, respectively, approximated 59%), 42%, and 0%, the last resulting from an absence of negative interpretations. Such error rates are unacceptable for tests that are used for critical decision-making in clinical care.

ISSN:0273-8481    

出版商:OVID    

年代:1982

数据来源: OVID

摘要:

Ratings of burn size and depth may be used to assess the severity of injury of patients in different institutions. These ratings may be used to adjust for differences in the severity of injury of patients when different institutions or levels of care are compared, or they may guide treatment decisions for individual patients.A study was undertaken of the comparability of ratings of the same patients given by different institutions in which records of patients transferred to the Regional Burn Treatment Center in San Diego were searched for the burn size and depth ratings given by the referring facility.When these ratings were compared to ratings given by the staff at the burn center, the data showed that the referring facility rated burn size about 5% larger on average.Comparisons of burn units or levels of care that use ratings of burn size and depth to adjust for the severity of injury of patients cannot be valid when different institutions give different ratings to burns of the same size.

ISSN:0273-8481    

出版商:OVID    

年代:1982

数据来源: OVID

摘要:

Hyperglycemia in burn patients is reviewed and the factors relating to its cause are discussed. A study on burn patients that attempts to define criteria for making the diagnosis is compared with studies from the more recent literature on hypermetabolism in thermal injury. A treatment regimen is outlined to control the burn patient who has nonketotic hyperglycemia

ISSN:0273-8481    

出版商:OVID    

年代:1982

数据来源: OVID