摘要:

Summary.Sublines of chickens differing in genotypes at the major histocompatibility complex (MHC) were developed from lines selected for high (HA) and low (LA) antibody response to sheep erythrocytes. To evaluate the influence of MHC genotypes in diverse background genomes on resistance to Marek's disease, chicks with MHC genotypes B13B13, B13B21and B21B21from both background genomes were exposed naturally commencing at 1 day of age. Individuals which died up to 120 days of age were autopsied to determine cause of death. Mortality due to Marek's disease was greater for HA than LA chickens and greater for males than females. Interactions of MHC genotypes with background genome and with sex suggest a complex picture of the influence of MHC genotypes. A heterozygous advantage for resistance to Marek's disease was noted, as would be predicted by genetic theory concerning maintenance of polymorphism at the MHC.

ISSN:0268-9146    

DOI:10.1111/j.1365-2052.1989.tb00896.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Summary.A number of horse alloantisera were characterized biochemically as being directed against MHC class I or class II antigens by immunoprecipitation of the corresponding antigens from lysates of biosynthetically radioactively labelled lymphocytes and determination of their molecular weights by SDS‐PAGE and fluorography. Sera recognizing A2 and A3 specificities precipitated antigens of 44000 Daltons molecular weight (class I heavy chain), whereas sera with specificities W13, W22 and W23 precipitated antigens corresponding to class II dimers (30000 and 32000 Daltons). Comparison with antigens precipitated from horse lymphocyte lysates using (cross‐reacting) antibodies to human class I and class II MHC molecules confirmed the results obtai

ISSN:0268-9146    

DOI:10.1111/j.1365-2052.1989.tb00897.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Summary.A study of 15 blood protein systems in fallow deer,Cervus damaL., has revealed a transferrin polymorphism in two German populations for the first time in this species. Genetic analysis of complete families suggests that the transferrin system is controlled by one gene locus with two codominant alleles. The comparison of the present results with other studies on this species leads to the hypothesis that at least the European mainland fallow deer populations are genetically more differentiated than previously assumed.

ISSN:0268-9146    

DOI:10.1111/j.1365-2052.1989.tb00898.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:0268-9146    

DOI:10.1111/j.1365-2052.1989.tb00899.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:0268-9146    

DOI:10.1111/j.1365-2052.1989.tb00900.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:0268-9146    

DOI:10.1111/j.1365-2052.1989.tb00901.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:0268-9146    

DOI:10.1111/j.1365-2052.1989.tb00902.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY