摘要:

Thirty‐two patients with transitory ischemic attacks (TIA), 55 with cerebral infarction (minor stroke) and one with a disturbing bruise underwent carotid endarterectomy during a 4 year period. Within the first 2 weeks postoperatively, 10 patients (11 %) had developed new neurological symptoms from the operated side. Two patients died postoperatively due to major stroke and 2 patients developed persistent neurological deficits, yielding a total operative mortality and permanent morbidity rate of 4.5 %. In the other 6 patients, the neurological signs and symptoms disappeared completely within one month.During a follow‐up for an average of 21 months, the only symptoms from the operated side were TIA in 3 patients, while 3 patients developed TIA and 5 infarctions from other vascular territor

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00774.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

28 patients with transient global amnesia (TGA) were followed for a mean period of 73 months. The patients fell into 3 diagnostic groups: a group where patients had associated symptoms and signs of transient focal cerebral ischemia (TIA), a migraine group and a miscellaneous group. 22 patients had evidence of cerebrovascular disease or risk factors for cerebrovascular disease, and a vascular basis for the amnesic attack was highly suggestive in 25 patients. During the follow‐up period 2 patients died, 3 had recurrent TGA and 13 developed a completed stroke or suffered from further TIA's. Permanent memory impairment was encountered in 9 cases. An unfavourable course was related to the presence of other TIA manifestations and/or risk factors for cerebrovascular disease.The study indicates that TGA is probably due to transient ischemia in the vertebrobasilar arterial distribution area. TGA per se has a good prognosis, but the coexistence of risk factor or manifest cerebrovascular disease implies a high rate of a subsequent completed stroke or permanent memory impairmen

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00775.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Temporal lobe epilepsy in particular has been considered a consequence of childhood febrile convulsions. Previous studies have dealt with populations of epileptic children. This retrospective, follow‐up study concerns 362 children with a primary diagnosis of febrile convulsions. 4% developed epilepsy. When followed into early adulthood one half of those remitted. The incidence of temporal lobe epilepsy among the non‐rermitters did not differ from that of a random population of epilept

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00776.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

The incidence of neurosyphilis in the Greater Copenhagen region was found to be 0.30 per 100,000 inhabitants per year within a 5 year period. This figure is higher than incidence found in other studies from the last decades, but does not represent a statistically significant rise.Using hospital records from relevant departments 23 patients were described. General paresis and meningovascular cases were the most common manifestations. A tendency towards a changing clinical pattern of neurosyphilis was confirmed.Dementia and personality changes were the most frequently observed clinical symptoms. The classical signs of tabes dorsalis were seen in only very few patients. Stroke was a common manifestation.We recommend Standard Serological Tests for Syphilis to be carried out in patients under 60 years of age with cerebrovascular diseases, dementia and in patients where neurosyphilis could be even a remote diagnostic possibility.

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00777.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Homovanillic acid (HVA), 5‐hydroxyindoleacetic acid (5‐HIAA) and 4‐hydroxy‐3‐methoxyphenylglycol (HMPG) were measured in the cerebrospinal fluid from patients with multiple sclerosis and from healthy volunteers. The fluid was withdrawn with the persons in the lateral recumbent position. In the controls and in 4 of the patients 10 successive samples of 2 ml each were analyzed. In the remaining patients the first 2 ml and last 2 ml of a total 20 ml were analysed. The highest values were obtained in the last portion. Patients with multiple sclerosis had significantly lower levels of 5‐HIAA than controls in both the first and last CSF samples. Patients with a progressive course or prominent residual symptoms had a lower concentration of 5‐HIAA and HVA than those with a relapsing course and little residual symptoms. The difference was significa

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00778.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Lumbar cerebrospinal fluid (CSF) from 30 cases of subacute sclerosing panencephalitis (SSPE) was studied for total protein and protein electrophoresis. Total CSF protein values were normal in almost all the cases, but theγ‐globulin was increased and had an oligoclonal morphology in all the cases. Absolute and relative values of some of the other electrophoretic fractions were decreased. Total protein and electrophoretic serum values in 25 cases did not differ significantly from the controls, although theγ‐globulin presented an oligoclonal morphology in 13 cases. CSF immunoglobulins were determined in 10 cases; IgG was increased in all; IgA was traceable and slightly increased in only four cases; IgM was not found. These findings point to the intrathecal synthesis of IgG and the absence of barrier impairment. The decrease of the absolute values of some of the other CSF proteins suggests that homeostatic mechanisms for protein concentration in the CSF are maintained in

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00779.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Plasma dopamine‐β‐hydroxylase activity (DBH) was estimated in 50 drug‐free Parkinson patients, 30 of whom had never been treated, in 26 patients treated chronically with L‐Dopa, and in 44 controls. 22 of the drug‐free patients were examined again after two weeks treatment with L‐Dopa plus decarboxylase inhibitor. In disagreement with other reports, no differences were found among the groups and no change in the enzyme activity occurred after treatment, although urinary homovanillic acid increased 20 fold. Low DBH activities could not be attributed to the age of onset or duration of illness, main symptom, depression, autonomic disturbances, or duration of drug treatment. The only difference was found in patients with dementia associated to their illness, who showed low enzym

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00780.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY