ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1970.tb05791.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1970.tb05792.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1970.tb05793.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

ABSTRACTTopographic studies were made on the fatty acid composition of umbilical cord serum, maternal serum, and breast milk, as well as foetal and neonatal brains by studying and comparing data of material obtained from Uganda, East Africa, with those obtained from a Danish material. The umbilical cord serum has a significantly lower content of C 18:2 than maternal serum, but a higher content of C 18:0, C 20:3, and C 20:4. Compared with normal female sera, the maternal sera showed lower concentrations of C 14:0 and C 18:2, but a higher content of C 16:0. When compared with a corresponding Danish material, the Ugandan samples showed lower concentrations of C 18:0, whereas only minor differences could be observed among the polyunsaturated fatty acids. A comparison between Ugandan and Danish breast milk showed higher values for C 12:0 and C 14:0 and lower values for C 16:1, C 18:0, and C 18:1 in the Ugandan samples. Ugandan colostrum contained less C 12:0 and C 14:0 but more C16:0, C 16:1, C 18:0, and C 18:1 than milk produced later in the lactation period. The poly‐unsaturated fatty acids were present in similar amounts in all the groups of milk studied here. No significant changes in the fatty acid composition of total brain or that of the isolated phospholipid fractions (choline‐, ethanolamine‐, and serine‐phospho‐glycerides) could be demonstrated during the foetal period studied. A possibly significant increase in C 20:4 and decrease in C 14:0 was seen in the ethanolamine‐phospho‐glyceride fraction. This fraction of neonatal brain contained more C 18:O and less C18:l than the fraction foetal brain (possibly significant), and the neonatal swine‐phospho‐glyceride fraction more C 18: 1 than the foetal one. Several significant differences were observed by comparison of these results with a simila

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1970.tb05794.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

ABSTRACTThe lipid composition of autopsy specimens from a patient suffering from Farber's disease (clinically verified) has been characterized and correlated to those of normal adult, infant, and foetal specimens. In autopsy specimens from the brain and liver tissue of the patient in question, an increased amount of an unknown glycolipid fraction and a phosphoglyceride fraction was found when the data was correlated to those of foetal and infant tissues. The glycolipid fraction was isolated by column chromatography and characterized chemically. This lipid was shown to contain glucose and galactosamine in the proportion of 4:1. Gas chromatography of the glycolipid revealed the presence of only shorter chain fatty acids, but only minor quantities of the C:22‐C:24 series. In addition, quantitative estimation of lipid soluble sialic (ganglioside) revealed about 30 per cent increase in sialic acid (ganglioside) in total brain tissue, but about 30 per cent decrease in liver tissue. The data obtained are discussed on the basis of the available literatur

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1970.tb05795.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

ABSTRACTCongenital myasthenia is reported in two siblings born to a non‐myasthenic mother. The major symptoms were confined to the eyes (symmetrical ptosis and external ophthalmoplegia), and the disease tended to remain stationary. In a review of the literature. 14 similar cases were found. Electromyography showed evidence of myopathie involvement, particularly in the eye muscles; a muscle biopsy from the right biceps muscle in one case revealed normal findings. Repetitive nerve stimulation, combined with a Tensilon (edrophonium) test, was in favor of the diagnosis of myasthenia. Although the possibility exists that such cases represent, myopathy with myasthenic features, the most likely possibility seems to be that the myopathic electromyographic changes are secondary to the myasthenia. It is emphasized that repetitive nerve stimulation and Tensilon test are important aids in the diagnosi

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1970.tb05796.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1970.tb05797.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

ABSTRACTThe data concerning the mortality in severe brain injury and the disability caused by it were analysed. We classified as severe those head injuries which caused unconsciousness for more than 24 hours. The series presented consists of 204 patients. The follow‐up time was from three to five years. The total mortality was 50 per cent, but increased steeply in older age groups. The mortality in patients over 60 years of age was 78 per cent, but among those under 20 years it was 38 per cent. Three years after the injury 43 per cent of the survivors were totally disabled. Less than 30 per cent of patients over 50 years of age were able to return to their former work, whereas more than 70 per cent of patients under 20 years were able to return to work or to school. It is concluded that in patients over 60 no special or heroic methods of treatment are indicated but that in children and adolescents every effort should be made as long as there has not been respiratory arrest and cerebral deat

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1970.tb05798.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1970.tb05799.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1970.tb05800.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY