摘要:

Sellar and parasellar tumours comprise 10–15 % of all intracranial neo‐plasms. Neurologists will thus often be faced with the problem of assessing pituitary function. A thorough clinical examination is of the foremost importance. In addition a small number of simple and rapid tests is required. Knowledge of the physiological variation in pituitary function is, however, necessary to allow a safe interpretation of the results. A simple routine procedure for assessing pituitary function is propo

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1979.tb02926.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Seven spinal cord injured patients were evaluated with cystometry bladder, electromyography, and pressure profiles of the external urethral sphincter before and after phenoxybenzamine administration. Seven more patients were evaluated before and after mecamylamine administration. Both drugs reduced the contractility of the bladder. The reduction of bladder contractility may reflect decreased sympathetic stimulation to the bladder. Bladder electric potentials reflect the intrinsic tone of the detrusor muscle.

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1979.tb02927.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

The calcification in a totally calcified pineal tumour was studied. Transmission electron microscopy indicated that the tumour was a pinealoma. The type of calcification was investigated by bright‐field and dark‐field transmission electron microscopy in addition to electron diffraction and electron‐induced x‐ray fluorescence. The calcified material consisted predominantly of amorphous calcium phosphate. This type of calcification differs from the normal calcification present in pineal acervuli which consists of crystalline hydrox

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1979.tb02928.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

There are few data in the literature suggesting that endogenous prostaglandins (PGs) might be involved in the pathomechanism of seizures. Since the mechanism of seizures inducted by exposure to oxygen high pressure (OHP) is not fully elucidated, this study was designed to investigate the effect of exogenous PG s and of indomethacin (a Pg synthesis inhibitor) upon the development and consequences of seizures in rats exposed to OHP (5 ata). In the animals pretreated with PGE2(1 mg/kg s.c.) pre‐seizure time was shortened, lung weight: body weight index increased and symptoms of respiratory failure potentiated, as compared with the control group. Indomethacin (5 mg/kg i.p) prevented the development of seizures. and of pulmonary consequences of OHP exposure. Biochemical examination of brains has shown that velocity of free radical oxidation of lipids (reactions manifested by the breakdown of phospholipid fatty acids, mainly unsaturated ones) enhanced by OHP exposure, is further potentiated in rats pretreated with PGE2. Electron microscopic study has shown the alterations similar to those seen in brain ischemia and/or hypoxia, and the magnitude of changes was related to the intensity of symptoms evoked by OHP. The results show that cerebral and pulmonary consequences of OHP exposure are potentiated by exogenous PGE2and prevented by inhibition of endogenous PG synthesis. This suggests that PGs and/or their active metabolites might be involved in the mechanism of oxygen toxicity during exposure to hyperbaric oxyge

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1979.tb02929.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Twenty unselected consecutive patients of filarial chyluria were evaluated clinically, electromyographically, and histopathologically for neuromuscular dysfunction. None of the patients showed clinical evidence of muscle wasting or weakness suggesting myopathy, although generalized muscle weakness was complained by all of them particularly while climbing the stairs or on getting up or during lifting heavy wieghts. Electromyographic abnormalities were found in nine patients and slight histopathological abnormalities in two. The average duration of motor unit potentials and the mean amplitude were reduced, compatible with myopathy. There were no fibrillation potentials. Histological abnormalities consisted of a marked variation in muscle fibre size, sarcolemmal nuclear proliferation, and mild interstitial fatty infiltration.None of the patients showed evidence of clinical neuropathy, abnormalities in conduction velocity along the nerves or signs of segmental demyelination in the biopsy of the nerve. Our data suggest that muscle weakness in these patients is myopathic in nature without peripheral nerve involvement, and is possibly due to hypoproteinaemia and hypolipidaemia, as these patients lose excessive amounts of protein and fat in their urine.

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1979.tb02930.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

On routine clinical examination it was observed that precussion over the thoracic spine occasionally produced reflex contraction of the intermediate and caudal parts of the trapezius muscle. The observation was made in one case of spondylitis and one case of inflammatory connective tissue disorder. Both patients had pain in the thoracolumbar regions. The neuro‐physiological features of this reflex have been analyzed. The incidence of the phenomenon in a randomly selected normal material was 3%. Electromyographic recording from the trapezius muscle demonstrated that the reflex is present at a subthreshold level in subjects not exhibiting the clinical reflex. The latter is established by pain and/or tension in the thoracolumbar paravertebral regio

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1979.tb02931.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

A young woman with firm evidence of early multiple sclerosis (MS), who had never had measles, developed a clinically and serologically evident measles infection. Follow‐up 1 year later confirmed the MS diagnosis. Thus, if measles can have a causal role in MS, it is probably not the only agent with this abilit

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1979.tb02932.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY