摘要:

The quantitative EEG (QEEG), regional cerebral blood flow (rCBF) and circulation time of 17 patients were examined semisimultaneously thrice during the first 3 months after a cerebral supratentorial infarction. The EEG was quantified according to normalized slope descriptor technique in nine patients and by means of a combined period and amplitude analysis in eight patients. Intravenously injected isotopes133Xenon and99TcmO4were used for blood flow and circulation time measurements. The QEEG‐values improved during the whole follow‐up period. Cerebral blood flow stayed low for all 3 months and did not alter during this period, while initially prolonged circulation time to some extent improved within 2 weeks remaining, however, prolonged even thereafter. A tendency for a positive correlation between QEEG and rCBF values in the infarcted hemisphere could be s

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00767.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

A retrospective follow‐up study of 243 patients with transient ischemic attacks (TIA) is reported. The long‐term mortality of the patients was higher than that of the corresponding general population. It is demonstrated that the excess mortality over the whole period of observation, irrespective of the age and sex of the patients, can be characterized by a single figure expressing the slope of the curve obtained by semilogarithmic plotting of the ratios of observed to expected survival against time. The use of this numerical expression – in the present series –0.04 – will thus facilitate comparisons of the survival of TIA patients drawn from different populations.Unfavourable prognostic factors were: carotid TIA, associated extra‐cerebral disease, and a history of hypertension. Fatal strokes, being four times as frequent as expected according to published incidence figures, accounted for 20 % of the deaths, heart disease 38 %. Stroke deaths tended to occur earlier than cardiac deaths.The results support the concept that most TIAs, like strokes, are incidents in the progressive course of a generalized vascular disease. The finding of a constant excess mortality over the years following a TIA makes it difficult to recommend a discontinuation of prophylactic therapy at any part

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00768.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Nineteen males with a well‐developed postconcussional syndrome were studied byCT‐scan, by psychometric testing and by endocrinological evaluation including a variety of laboratory tests and an assessment of sexual function. 68 % had cerebral atrophy onCT‐scanand 79 % were intellectually impaired, 37 % to a severe degree. Sexual dysfunction (reduced libido and/or erective dysfunction) related to the head injury occurred in 58 %, and severe intellectual impairment was significantly more frequent in this group. Increased plasma concentration of follicle stimulating hormone was observed in 37 %, suggesting a reduced spermiogenesis. The possibility of a primary hypothalamic disorder causing reduced spermiogenesis is raised. Otherwise no radiological or laboratory evidence of major hypothalamic‐pituitary dysfunction was demonstrated. The high frequency of cerebral atrophy and intellectual deterioration in postconcussional syndrome suggests organic brain dysfunction, but no causal relationship was esta

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00769.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Thirty‐six males with erective impotence underwent neurological and urological examinations. Six of the patients were known to have a neurological disorder at the time of referral (four multiple sclerosis, one myelomeningocele, one diabetic polyneuropathy). Four further cases of neurological disorders were found (one multiple sclerosis, one myelopathy of unknown cause, one Shy‐Drager syndrome, one sequelae of sacral herpes zoster). Five of these 10 patients gave a history of urinary troubles, but in all of them objective signs of bladder dysfunction were found at cystometry and/or mictometry. Among the 26 patients with impotence and no indication of a neurological disorder all invariably had normal cystometrograms, though some had abnormal mictiograms, probably due to local urological disorders.A neurological examination should be included in the evaluation of patients with erective impotence. Cystometry and mictometry may be of value by giving additional indications that the impotence is neurogenic. This is explained by the fact that the anatomical structures regulating sexual function lie close to corresponding structures regulating bladder function at the spinal le

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00770.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Rats withdrawal from long‐term diphenylhydantoin treatment (DPH) were tested for their sensibility to convulsant stimuli. Animals were more sensitive to convulsions elicited by maximal electroshock and sound, respectively, at 48 and 72 h after drug removal. These results suggest that long‐term DPH treatment might develop a central nervous system supersensitivity st

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00771.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

The relative compositions of free fatty acids (FFA) in white matter from six multiple sclerosis (MS) and seven control brains were determined by gas chromatography. The major components of all samples were oleic, stearic and palmitic acids, with lesser amounts of arachidonic acid, and a long chain fatty acid, identified as 24:4. MS samples had significantly less of the 24:4 fraction compared with controls, but no other differences were noted. The spectrum of FFA was similar in most respects to those reported for phosphatidylcholine and cholesterol esters. This supports current theories that a major pathway of lipid catabolism in the brain involves transfer of fatty acids from phosphatidylcholine to cholesterol.

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00772.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Books review in this article:Neurotransmitters, receptors and drug action. Ed. byW. Essman.Sz. Donhoffer:Homeothermia of the brain.British Medical Bulletin: Diagnostic imaging. Ed. byL. Kreel.N. H. Raskin&O. Appenzeller:Headache. The book is volume XIX in the series Major Problems in Internal Medicine, edited by Lloyd H. SchmithCurrent topics in extrapyramidal disorders. Ed. by A. Carlsson, K. Jellinger&P. Riederer.Epilepsie 1979. Ed. by H. Doose, M. Dam, G. Gross‐Selbeck&H. Meinardi.Addiction and brain damage. Ed. byD. Richter.The year book of neurology and neurosurgery. Ed. by R. N. DeJong&O. Sugar.B. Pansky&D. J. Allen:Review of neuroscience.J. A. Aarli&O. Tönder:Immunological aspects of neurological diseases.Spinocerebellar degenerations. Ed. byI. Sobue.M. J. Eadie&J. H. Tyrer:Neurological clinical pharmacology.The treatment of epilepsy. Ed. byJ. H. Tyrer.Neurological mutations affecting myelination. Ed. byN. Bauma

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1981.tb00773.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY