摘要:

ABSTRACT—Visual, brainstem auditory and somatosensory evoked potentials to medial nerve stimulation were recorded in 27 patients affected by amyotrophic lateral sclerosis. VEP N75, P100, N140, N75‐P100 latencies and P100 amplitude, BAEP I‐III, III‐V and I‐V interpeak‐latencies were within normal limits in all ALS patients. Somatosensory evoked potentials were abnormally delayed in 8 patients: in 3 arms because of a delayed N9‐N13 latency, in 9 arms because of a delayed N1

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1989.tb03799.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT—We report 4 cases of migraine‐related stroke in young females. Two patients were taking oral contraceptives and one was pregnant. The results of the computerized tomography of the brain were negative in 3 patients and partially positive in one, while NMR showed ischemic lesions in the posterior fossa in each case. We would like to highlight the value of NMR in the assessment of migraine associated with prolonged focal neurologic deficiencies when the clinical examination revealed brain stem or cerebellar signs and the peculiar localization of the ischemic lesion that corresponded in all 4 cases to the area irrigated by the superior cerebellar artery. An hormonal factor is suspected as the precipitating event of this complication in 3 of these patie

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1989.tb03800.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT—We present a case of subacute meningoencephalitis associated with human T‐lymphotrophic virus Type I (HTLV‐I) infection, for HTLV‐I antibody being positive in serum and cerebrospinal fluid. Necropsy findings disclosed leptomeningeal and parenchymal mononuclear cell infiltration with multinucleate giant cells, which are similar to those seen in subacute encephalitis with acquired immunodeficiency syndrome

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1989.tb03801.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT—An epidemiological survey of the prevalence of snoring and sleep apnoeas was performed on 3479 30‐69‐year‐old men living in Bologna, north‐east Italy. First a postal questionnaire was sent. It was returned with appropriate answers by 1170. A 20% random sample of those who did not answer were invited by telephone to return the questionnaire. Among these groups 119 (10%) and 19 (5.6%) respectively answered that they always snored. A random sample of 40 every‐night snorers were studied by polysomnography. Based on the frequency of every‐night snoring and the results of polysomnography we estimated that the minimal prevalence of sleep apnoea among 30‐69‐year‐old men was 2.7% considering an apnoea + hypopnoea index of 10 or more pathological. According to the Lugaresi classification we had a 2.5% prevalence of heavy snorers’ disease (HSD) Stage 1 or higher. These figures indicate that obstructive sleep apnoea during sleep is a major

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1989.tb03802.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT—Zinc (Zn), copper (Cu) and magnesium (Mg) concentrations in cerebrospinal fluid (CSF) and serum were determined with atomic absorption spectrophotometry in 74 patients suffering from various neurological diseases, and in 28 healthy controls. Increased CSF zinc levels were found in the group of peripheial nervous system diseases (P<0.01) and in the cases of different neurological syndromes with increased CSF protein concentration (P<0.001). Increased CSF and serum copper levels were found in the cases with increased CSF protein levels (P<0.05). It is probable that the damaged blood‐brain‐barrier (BBB) permits the passage of the trace elements Zn, Cu and of Mg into the subarachnoid space. Decreased serum Cu levels (P<0.01) were found in the group of multiple sclerosis (MS). The findings are correlated to those of previous communica

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1989.tb03803.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT—Accelerometric tremorgrams were recorded from 25 subjects affected by essential tremor and analysed by a Berg‐Fourier frequency analyser before and during venous infusion of the following drugs: propranolol (β‐blocker), clonidine (alpha‐presynaptic adrenergic agonist), urapidil (alpha‐postsynaptic blocker), trazodone (adrenolytic agent) and placebo. The washout interval between infusions was 3 days. Recordings and data analyses were performed in a double‐blind crossover trial. Tremor was classified as: at rest; postural (arms hyperextended); and intention (finger‐nose test). Analysis of the results showed that propranolol and clonidine reduced significantly (P= 0.01 andP= 0.009, respectively) the power spectrum of postural tremor, but left at rest and intention tremors unchanged. No significant effects on the tremor power spectrum were observed after placebo, urapidil or trazodone administration. None of the drugs had any effect on tr

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1989.tb03804.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT—The stretch reflex should ideally be quantitated for better clinical use by standardizing the muscle stretch and measuring the resulting muscle contraction. Quantitation of muscle contraction can be done by force measurements or electromyographic recordings. The electromyographic response to stretch consists of one component (short latency response) for short stretches (<15 ms) and of 2 or 3 components (short and long latency responses) for longer stretches (<40–50 ms). The magnitude of the phasic stretch reflex is reflected by the short latency response, whereas the magnitude of the tonic stretch reflex is reflected by both the short and the long latency responses. In clinical studies of upper motor neuron syndromes, the knee jerk and the muscle tone correlated with the magnitude of the short latency response. In patients with paralysis agitans an increased long latency response, which correlated to the rigidity, was fo

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1989.tb03805.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT—A Chinese family with at least 3 members having the typical clinical picture of type I familial amyloid polyneuropathy is presented. The pathological features, including the immunohistochemical typing of the amyloid deposits, are described and the literature is briefly reviewe

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1989.tb03806.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT—Brain tissue from 9 severely demented patients cared for in psychiatric long‐term wards and with records of stroke episodes, macroscopic signs of brain infarcts and with no clinical evidence of senile dementia of the Alzheimer type was investigated and compared with control material. The mean volume of the brain infarcts in this vascular dementia group was only 6.8 ml. Pronounced disturbances of the serotoninergic and cholingergic systems were found in subcortical and cortical grey matter. These widespread neurotransmitter changes can hardly be explained by the localized brain infarctsper se, but suggest the existence of another category of vascular dementia. Since the neurotransmitter disturbances were found to be similar to those of Alzheimer's disease and senile dementia of the Alzheimer type, it seems more likely that they indicate a common pathway for dementia disorders than that they serve as markers of different dementia categor

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1989.tb03807.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT—EEGs of 42 patients with herpes zoster and 6 with herpes zosterassociated encephalitis were studied to characterize the nature and prevalence of EEG abnormalities in apparently uncomplicated herpes zoster. Thirty‐one percent of herpes zoster patients had EEG changes with reduced rhythm frequency ranging from 7 to 2 Hz activity. Frontotemporal localization was observed in 54% of the abnormal EEGs. When compared to EEG in herpes zoster associated encephalitis, the findings were qualitatively the same, but tended to be more severe in the encephalitis cases. No effect of acyclovir on the EEG could be demonstra

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1989.tb03808.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY