摘要:

Visual evoked potentials (VEPs) by checkerboard pattern‐reversal stimulation were recorded in 70 subjects aged 10–69 years and in 100 patients with definite, probable or possible multiple sclerosis (MS). Longer latencies and smaller amplitudes of the major positive component were found in male subjects, in old subjects and when the amplifier's band‐pass was narrowed. Subjects 10–14 years old had longer latencies and higher amplitudes than mature adults. Based on findings in the normal material, the following three criteria were used in evaluating the recordings from patients: the latency, the side difference in latencies and the ratio of amplitudes between the two sides of the major positive component with various limits for the two sexes and different age groups.The incidence of abnormal recordings was 85% for all the patients, 100% in 50 patients with definite, 70% in 50 patients with probable or possible MS, 73% in patients who had a history of spinal symptoms only, 98% if they had and 74% if they had not experienced optic neuritis. The incidence of abnormal findings increased with increasing duration of symptoms. All patients with visual acuity below 0.67 had abnormal VEPs.The high incidence of abnormal recordings confirmed the value of the test in establishing the diagnosis, and suggested that the use of different normative values for sex and age may increase the diagnostic yield without increasing the number of false positive f

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1980.tb02998.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1980.tb07686.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1980.tb07687.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1980.tb07679.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1980.tb07669.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

The diagnostic value of the checkerboard pattern‐reversal visual evoked potential (VEP) and the random, low rate stimulated brain stem auditory evoked potential (BAEP) was compared in 99 patients with established or suspected multiple sclerosis (MS). In normal subjects examined by both techniques no abnormal recordings were found. In 49 patients with definite MS an incidence of abnormality was found in 100% of VEP and in 84% of BAEP recordings. In 50 patients with probable or possible MS an abnormal VEP was found in 70% and an abnormal BAEP in 50%. When the two examinations were combined, the diagnostic yield increased to 100 and 80%, respectively. 22 patients had only spinal symptoms; in these the VEP gave 73%, the BAEP 55% and the combination 82% abnormalities. The combination of the two techniques was found useful for demonstrating demyelinating lesions in the central nervous system, the diagnostic value being greatest when these lesions were clinically silen

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1980.tb02999.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1980.tb07688.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1980.tb07670.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1980.tb07671.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0001-6314    

DOI:10.1111/j.1600-0404.1980.tb07672.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY