摘要:

AbstractThe peroxyacid oxidation of 6‐chloro‐2,4‐diaminopyrimidine (1) led to two products, 6‐chloro‐2,4‐diaminopyrimidine 3‐N‐oxide (2) and 2,4‐diamino‐5,6‐dichloropyrimidine 3‐N‐oxide (3). The assignment of structure of both of these compounds was made on the basis of ir, uv, nmr, and mass spectral data. A discussion of the pathways involved in the

ISSN:0022-152X    

DOI:10.1002/jhet.5570090111

出版商:Wiley‐Blackwell    

年代:1972

数据来源: WILEY

摘要:

AbstractThe 1,2‐cycloaddition of nitrosoarenes to ketenimines producing 3‐iminosubstituted‐1,2‐oxazetidines has been found to proceed more rapidly if photosensitized conditions are employed. This data plus the specificity of the reaction allows for a reasonable postulation of the non‐photochemical room temperature

ISSN:0022-152X    

DOI:10.1002/jhet.5570090112

出版商:Wiley‐Blackwell    

年代:1972

数据来源: WILEY

摘要:

AbstractThe diazaanalog of “cycl[3,2,2]azine”, “1,4‐diazacycl[3,2,2]azine” (1,4,7b‐triazacyclopent‐[cd]indene) and its 2‐methyl derivative were prepared. These compounds are subject to facile acid‐catalyzed hydrolysis affording substituted imidaz

ISSN:0022-152X    

DOI:10.1002/jhet.5570090113

出版商:Wiley‐Blackwell    

年代:1972

数据来源: WILEY

摘要:

AbstractPhenylacetonitrile (2) (32%) and small amounts of benzyl methyl ether (3), benzonitrile (5) and methyl benzoate (6) were produced by irradiation of either 4‐phenyl‐1,2,3‐triazole (1) or 4‐phenyl‐5‐deutero‐1,2,3‐triazole (7) in methanol at 254 nm. In methylene chloride, irradiation of1produced2(15%) and small amounts of 3,6‐diphenyl‐1,2,4,5‐tetrazine (8). Irradiation of 4,5‐diphenyl‐1,2,3‐triazole (9) in methanol gave 2,4,5‐triphenylimidazole (11) (4%) and trace amounts of diphenylacetonitrile (10), benzamide (12), and compounds3,5, and6. Irradiation of 2,3‐diphenyl‐2H‐azirine (13) in methanol gave small amounts of3, benzaldehyde (4), and compounds5,6,12as well as 2,3,5,6‐tetraphenylpyrazine (14) and in methylene chloride it gave11(16%) and small amounts of4,5,14, and acetophenone (15).On heating 4‐phenyl‐1,2,3‐triazole (1) inn‐hexadecane, elimination of nitrogen at 290° left phenylacetonitrile (2) as the only identified product. Similar pyrolysis of 4,5‐diphenyl‐1,2,3‐triazole (9) produced 2,3,5,6‐tetraphenylpyrazine (14) along with an intractable material. An efficient thermal isomerization of

ISSN:0022-152X    

DOI:10.1002/jhet.5570090114

出版商:Wiley‐Blackwell    

年代:1972

数据来源: WILEY

摘要:

AbstractTwo alternative synthetic routes were investigated for the synthesis of 2,4,10‐substituted‐7,8‐dimethylpyrimido[5,4‐b]quinolines: (1) cyclization of 5‐(3,4‐xylidino)‐2,4‐disubstituted‐pyrimidine‐6‐carboxylic acids, and (2) cyclization ofN‐5‐(2,4‐disuhstituted‐pyrimidinyl)‐4,5‐dimethylanthranilic acids. Route (1) invariably led to isomeric mixtures of the corresponding 7,8‐ and 8,9‐dimethylpyrimido[5,4‐b]quinolines which were difficult to separate, while route (2) yielded only the desired 7,8‐dimelhyl derivatives. The required intermediates were synthesized by Ullman‐type condensation of the appropriate pyrimidine and benzene derivatives. Cyclization with polyphosphoric acid, or phosphorus oxychloride (under various conditions) led to a number of new pyrimido[5,4‐b]quinoline derivatives, with oxo, methoxy and/or chloro substituents in the 2,4 and 10 positions. A mild, but effective chlorination procedure was developed for the chlorination of the 10‐(oxo) position without the c

ISSN:0022-152X    

DOI:10.1002/jhet.5570090115

出版商:Wiley‐Blackwell    

年代:1972

数据来源: WILEY

摘要:

AbstractSeveral isomers are possible when an isocyanate or an isothiocyanate is allowed to react with 3‐amino‐1,2,4‐triazole. It was found that variations in reagents or reaction conditions could be used to produce isomeric derivatives. The effect of substituents on the chemical shifts of adjacent ring protons is described for a number of new triazole derivatives. These data can be used to assign structures to newsym‐triazole reaction products. Appropriate triazoles were used as intermediates in the synthesis ofs‐triazolo[1,5‐a]‐s‐triazine (5‐azapurine) derivatives. Spectral properties, methods of synthesis, and modes of degradation are described for several new members of

ISSN:0022-152X    

DOI:10.1002/jhet.5570090116

出版商:Wiley‐Blackwell    

年代:1972

数据来源: WILEY

ISSN:0022-152X    

DOI:10.1002/jhet.5570090117

出版商:Wiley‐Blackwell    

年代:1972

数据来源: WILEY

ISSN:0022-152X    

DOI:10.1002/jhet.5570090118

出版商:Wiley‐Blackwell    

年代:1972

数据来源: WILEY

ISSN:0022-152X    

DOI:10.1002/jhet.5570090119

出版商:Wiley‐Blackwell    

年代:1972

数据来源: WILEY

ISSN:0022-152X    

DOI:10.1002/jhet.5570090120

出版商:Wiley‐Blackwell    

年代:1972

数据来源: WILEY