摘要:

AbstractOptically active(S)‐2‐(2‐methylbutyl)thiophene was obtained by different procedures. Among them, the cross‐coupling reaction between 2‐methylbutylmagnesium chloride and 2‐chlorothio‐phene proved to be the most efficient one. Compound1was thus obtained in satisfactory yield and rather high optical

ISSN:0022-152X    

DOI:10.1002/jhet.5570170111

出版商:Wiley‐Blackwell    

年代:1980

数据来源: WILEY

摘要:

AbstractCycloaddition of dichloroketene toN,N‐disubstituted 3‐aminomethylene‐4‐chromanones gave in good yieldN,N‐disubstituted 4‐amino‐3,3‐dichloro‐3,4‐dihydro‐5H‐pyrano[3,2‐c][1]benzopyran‐2‐ones only in the case of aromaticN‐substitution. Dehydrochlorination with triethylamine of these adducts affordedN,N‐disubstituted 4‐amino‐3‐chloro‐5H‐pyrano[3,2‐c][1]benzopyran‐2‐ones in good to moderate yield. The cycloaddition to 3‐dimethylaminomethylene‐4‐chromanone led directly to 3‐c

ISSN:0022-152X    

DOI:10.1002/jhet.5570170112

出版商:Wiley‐Blackwell    

年代:1980

数据来源: WILEY

摘要:

AbstractThe syntheses of the 7‐chloro‐, 4,7‐dichloro‐, 5‐ and 7‐trifluoromethyl, 5‐chloro‐6‐trifluoro‐methyl‐ and 5‐chloro‐7‐trifluoromethyl‐ derivatives of 3‐amino‐2,1‐benzoisothiazole are described. Preparative details are included for a number of the precursors to the benzoisothiazole derivative which have not previously been described. Visible spectra of some azo dyes prepared from the title compounds with a selected coupler are discussed with r

ISSN:0022-152X    

DOI:10.1002/jhet.5570170113

出版商:Wiley‐Blackwell    

年代:1980

数据来源: WILEY

摘要:

AbstractThe synthesis of the alkaloid cryptopleurine7bhas been accomplished by a sequence involving as a key step the selective Borch reduction of an amidoester1bto the corresponding aminoester2b.This route is applicable to the synthesis of derivatives such as7a.

ISSN:0022-152X    

DOI:10.1002/jhet.5570170114

出版商:Wiley‐Blackwell    

年代:1980

数据来源: WILEY

摘要:

AbstractThe reaction of benzoylacetonitrile(III), its phenylazo derivative(X), malononitrile and malononitrile derivatives with ethyl hydrazinoacetate was investigated. All the investigated compounds with the exception of phenylazobenzoylacetonitrile and phenylazomalononitrile afforded 1‐ethoxycarbonylmethyl‐3‐aminopyrazole derivatives when treated with I. Compounds Xa andXVIIIafforded imidazoypyrazole derivatives under the same experimental condi

ISSN:0022-152X    

DOI:10.1002/jhet.5570170115

出版商:Wiley‐Blackwell    

年代:1980

数据来源: WILEY

摘要:

AbstractThis paper describes the synthesis of the previously unknown 11H‐1,2,4‐triazolo[4,3‐b]pyridazino[4,5‐b]indoles(2)and 11H‐tetrazolo[4,5‐b]pyridazino[4,5‐b]indoles(3)from 4‐hydrazino‐5H‐pyridazino[4,5‐b]indoles(1), as well as the synthesis of 1,2,4‐triazolo[3,4‐f]‐1,2,4‐triazino‐[4,5‐a]indoles(10)from 2‐indolecarbohydrazide(4). Compounds2were obtained by acylation of compounds1, followed of thermal cyclization and compounds3by treating compounds1with nitrous acid. The reactions of compound4with formic acid or ethyl orthoformiate gave 1,2‐dihydro‐1‐oxo‐1,2,4‐triazino[4,5‐a]indole(6). Treating this last compound with phosphorus oxychloride or phosphorus pentasulfide, followed by hydrazine, gave 1‐hydrazino‐1,2,4‐triazino‐[4,5‐a]indole(9). Acylation of this last compound, followed of cyclization gave compounds10. All the compounds were cha

ISSN:0022-152X    

DOI:10.1002/jhet.5570170116

出版商:Wiley‐Blackwell    

年代:1980

数据来源: WILEY

摘要:

AbstractThe electron impact mass spectrometric fragmentation pathways for some 3‐substituted derivatives of coumarin, benzo[f]coumarin, thieno[3,2‐f]coumarin, thieno[2,3‐h]coumarin and azacoumarin,viznitriles, carboxamides, thiocarboxamides and esters were investigated. The initial cleavage of the pyrone ring is found to be largely dependent on the stability, under electron impact, of the attached functional

ISSN:0022-152X    

DOI:10.1002/jhet.5570170117

出版商:Wiley‐Blackwell    

年代:1980

数据来源: WILEY

摘要:

AbstractCyclization of γ‐(2‐thienyl)butryic acid with acid anhydrides gives 2‐acyl derivatives as well as the expected 6,7‐dihydrobenzo[b]thiophen‐4(5H)one. Several reactions of these ketones have been studied including their conversion to 0,0‐diethyl thiophosphonohydrazones. 7‐Substituted thieno[2,3‐h][1]benzopyran‐8‐ones have been preparedvia4‐hydroxybenzo[b]th

ISSN:0022-152X    

DOI:10.1002/jhet.5570170118

出版商:Wiley‐Blackwell    

年代:1980

数据来源: WILEY

摘要:

AbstractCe travail décrit une approche permettant de parvenir à des hétérocycles indoliques tri et tétracycli

ISSN:0022-152X    

DOI:10.1002/jhet.5570170119

出版商:Wiley‐Blackwell    

年代:1980

数据来源: WILEY

摘要:

AbstractDiimmonium salt(5)reacts with guanidines(6)ando‐methylisoureas(7)affording 2‐amino‐4,5‐dimorpholinoimidazolines(9). 1‐Aryl‐2‐amino‐4,5‐dimorpholinoimidazolines lose the amino functionality under mild acidic conditions with formation of 2‐amino‐5‐morpholinoimidazole derivatives(10)whereas 1‐acyl derivatives undergo under the same conditions a ring expansion process leading to p

ISSN:0022-152X    

DOI:10.1002/jhet.5570170120

出版商:Wiley‐Blackwell    

年代:1980

数据来源: WILEY