摘要:

AbstractThe fragmentation patterns of seven oxadiazolines (compounds I‐VII) were obtained from mass spectral data. Fragmentationsaandb(Figure 1) are more important thanc.Some of the novel cracking pathways are discusse

ISSN:0022-152X    

DOI:10.1002/jhet.5570050111

出版商:Wiley‐Blackwell    

年代:1968

数据来源: WILEY

摘要:

AbstractSyntheses, and infrared and nuclear magnetic resonance spectral data for the six mononitrobenzo[b] thiophenes are described. Sulfonation of benzo[b] thiophene has been demonstrated to produce the 2‐ and 3‐isom

ISSN:0022-152X    

DOI:10.1002/jhet.5570050112

出版商:Wiley‐Blackwell    

年代:1968

数据来源: WILEY

摘要:

AbstractThe sodium borohydride reduction of bothcisandtrans‐1‐cyclohexyl‐2‐phenyl‐3‐aroylaziridines provides in each case the corresponding carbinol as a mixture of the two possible diastereoisomeric racemates, whereas reduction of these ketones with lithium aluminum hydride or with lithium diisopropylamide provides only the racemate resulting from attack on the carbonyl group from the least hindered side. Catalytic hydrogenation of acisaziridinyl ketone cleaved the aziridine ring and provided an ami

ISSN:0022-152X    

DOI:10.1002/jhet.5570050113

出版商:Wiley‐Blackwell    

年代:1968

数据来源: WILEY

摘要:

AbstractThis paper describes the synthesis of the various picrylamino‐ and nitro‐substituted furazans and bifurazanyls. Except for 3,4‐bis(picrylamino)furazan, which was obtained by nitrating 3,4‐dianilinofurazan, the picrylaminofurazans were prepared by condensing the appropriate amino‐furazan with picryl fluoride in the presence of triethylamine. The various aminofurazans were oxidized with peroxytrifluoroacetic acid to the corresponding nitro de

ISSN:0022-152X    

DOI:10.1002/jhet.5570050114

出版商:Wiley‐Blackwell    

年代:1968

数据来源: WILEY

摘要:

Abstract1‐(2‐Mercaptoethyl)phthalazine (VII) and its analogs such asS‐2‐(1‐phthalazyl)ethyliso‐thiuronium bromide (VI), sodiumS‐2‐(1‐phthalazyl)ethylthiosulfate (VIII), 1,3‐bis‐acetylthio‐2‐(1‐phthalazyl)propane (XII), 2‐(1‐phthalazyl)‐1,3‐propanedithiol (XIII), disodium 2‐(1‐phthalazyl)‐1,3‐propanedithiosulfate (XIV), 3‐dimethylamino‐2‐(1‐phthalazyl)‐1‐propanethiol (XVII) and 3‐(4‐methyl‐1‐piperazinyl)‐2‐(1‐phthalazyl)‐1‐propa

ISSN:0022-152X    

DOI:10.1002/jhet.5570050115

出版商:Wiley‐Blackwell    

年代:1968

数据来源: WILEY

摘要:

AbstractThe preparation of 5‐trifluoromethylfurfural and some of its derivatives is described. Biological activity of the derivatives is reporte

ISSN:0022-152X    

DOI:10.1002/jhet.5570050116

出版商:Wiley‐Blackwell    

年代:1968

数据来源: WILEY

摘要:

AbstractThe thiazolidine, 1‐thia‐4‐azaspiro[4,5] decane (Ia), which is derived from cyclohexanone and 2‐aminoethanethiol (X), forms a thiazolidone (VIII) with mercaptoacetic acid more slowly and in lower yield than with 2‐phenylthiazolidine, a case reported previously. A thiazolidine which is related to a non‐conjugate chain tautomer such as Ic, might be expected to behave in this way. Alkylation, as another possible example of tautomer chemistry, was studied, andN‐, S‐, andC‐alkylation were all observed under varying circumstances. Thus, thiazolidine la undergoes alkylation with methyl iodide in ethanol to form theN‐methylthiazolidine (IIa), and in sodium‐liquid ammonia to give theS‐methyl derivative (III). In the latter case, alkylation occurs with reductive cleavage. Although no trace of other tautomer derivatives (IV, V) was to be found in the methyl iodide alkylation, I with acrylonitrile did in fact giveC‐alkylation. An analytically pure mixture of tautomers was obtained, from which 2‐oxocyclohexanepropionitrile (VI) was isolated on hydrolysis. In a manner similar to the formation of III, IIa wasS‐alkylated by treatment with sodium‐liquid ammonia followed by benzyl chloride to give a saturated product (XVII). Although such a process might be identified with a chain tautomer (IIb), the evidence is to the contrary, since the intermediate (XIV), which might be involved in such a process, fails to undergo a similar reduction with sodium‐liquid ammonia. A greatly improved procedure for the preparation of thiazolidine

ISSN:0022-152X    

DOI:10.1002/jhet.5570050117

出版商:Wiley‐Blackwell    

年代:1968

数据来源: WILEY

ISSN:0022-152X    

DOI:10.1002/jhet.5570050118

出版商:Wiley‐Blackwell    

年代:1968

数据来源: WILEY

ISSN:0022-152X    

DOI:10.1002/jhet.5570050119

出版商:Wiley‐Blackwell    

年代:1968

数据来源: WILEY

ISSN:0022-152X    

DOI:10.1002/jhet.5570050120

出版商:Wiley‐Blackwell    

年代:1968

数据来源: WILEY