摘要:

AbstractAlthough various methods of oxepine formation from phenoxybenzene dicarboxylic acids was attempted, only 11‐hydroxy‐4‐isobutoxy‐7,8‐dimethoxydibenz[b,f]oxepin‐l‐ylaeetic acid lactone (XXX) was synthesized successfully. Compound XXX gaveO‐isobutylcularidine (XXXVlIb) in a few steps. Our syntheticO‐isobutylcularidine was identical with that prepared from natural cularidine proving the structure for cularidine proposed by Manske. However, dealkylation of syntheticO‐isobutylcularidi

ISSN:0022-152X    

DOI:10.1002/jhet.5570060111

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

Abstract3‐Substituted pyridines (bearing vinyl, ethyl, α‐hydroxyethyl, and acetyl substituents) react with hydrogen sulfide at 630° to give low yields of thieno[2,3‐b]pyridine and thieno[3,2‐c]‐pyridine. For 3‐vinylpyridine as substrate, it is proposed that a free‐radical process is involved in

ISSN:0022-152X    

DOI:10.1002/jhet.5570060112

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractThe addition of substituted anilines to methyl propiolate produces labilecis‐transmixtures of enamines which can be isomerized by acid, solvent variation, and thermal techniques. Thermal cyclization of these enamines provides a synthesis of 4( lH)‐quinolo

ISSN:0022-152X    

DOI:10.1002/jhet.5570060113

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

Abstractδ‐Hydroxyamides, prepared by condensation of ketones or aldehydes at the 2‐methyl group ofNsubstitutedo‐toluamides by means ofn‐butyllithium, were cyclodehydrated with sulfuric acid to form 2,3‐disubstituted and 2,3,3‐trisubstituted 3,4‐dihydroisocarbostyriIs. Also, δ‐hydroxyamides obtained from condensation of ketones at the 2‐benzyl group ofN‐methyl‐o‐benzylbenzamide, were cyclodehydrated to give 2,3,3,4‐tetrasubstituted 3,4‐dihydroisocarbo‐styrils. All of the products appeared to be new. This new method, which involves an unusual acid catalyzed cyclodehydration, is convenie

ISSN:0022-152X    

DOI:10.1002/jhet.5570060114

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractThe preparation ofN1(2,3‐O‐isopropylidene‐β‐D‐ribofuranosyl)‐4‐quinazolone (6) andN3‐β‐D‐ribofuranosyI‐4‐quinazolone (3b) are reported. TheN3derivative was prepared by the direct condensation of 4‐trimethylsilyloxyquinazoline (2) and 2,3,5‐tri‐O‐benzoyl‐D‐ ribofuranosyl bromide. TheN1derivative was prepared from the previously reportedN1‐β‐D‐ribofuranosyl

ISSN:0022-152X    

DOI:10.1002/jhet.5570060115

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractSeveral pyridazines have been prepared as intermediates in the synthesis of monosubstituted imidazo[4,5‐d]pyridazines, monosubstitutedv‐triazoIo[4,5‐d]pyridazines and monosubstituted pyrazino [2,3d] pyridazines. The new ring system, 7H‐imidazo[4,5‐d]tetrazolo[l,5‐b] pyridazine (XIV) has been prepared unsubstituted. Furthermore, unsubstituted imidazo[4,5‐d]pyridazine (XI) has been prepared. Calculations for XI and XIV were made by approximate SCF LCAO‐MO with

ISSN:0022-152X    

DOI:10.1002/jhet.5570060116

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

ISSN:0022-152X    

DOI:10.1002/jhet.5570060117

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

ISSN:0022-152X    

DOI:10.1002/jhet.5570060118

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

ISSN:0022-152X    

DOI:10.1002/jhet.5570060119

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

ISSN:0022-152X    

DOI:10.1002/jhet.5570060120

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY