摘要:

Abstract2‐Imino‐1,3‐thiazetidines and 2‐imino‐1,3‐dithietanes were synthesized and their reactivities were studied. The former readily underwent ring‐opening reaction with amines to yield guanidine derivatives. The reaction products were applied to the synthesis of heterocycles such as triazoles and triazines. The latter was converted to isothiocyanate by the reaction ofm‐chloro

ISSN:0022-152X    

DOI:10.1002/jhet.5570280131

出版商:Wiley‐Blackwell    

年代:1991

数据来源: WILEY

摘要:

AbstractReaction ofm‐terphenyl with 20% oleum at 100° gives both disulfonation and double sulfonyl bridging to yield benzo[1]thieno[2,3‐b]dibenzothiophene‐3,9‐disulfonic acid 5,5,7,7‐tetraoxide, isolated as the disodium salt (24%) and convertible (viathe disulfonyl chloride) to the bis‐sulfonanilide (44%) and the bis‐N‐butylsulfonamide (40%). Analogously, reaction ofm‐terphenyl with chlorosulfonic acid at 100° gives disulfonation plus only single sulfonyl bridging to produce 2‐(4‐chlorosulfonyl)‐7‐chlorosulfonyldibenzothiophene 5,5‐dioxide (80%), convertible to the corresponding bis‐sulfonanilide (63%) and t

ISSN:0022-152X    

DOI:10.1002/jhet.5570280132

出版商:Wiley‐Blackwell    

年代:1991

数据来源: WILEY

摘要:

AbstractA convergent synthesis of 1,8‐naphthyridine antibacterials bearing a carbon‐carbon bonded, acyclic or cyclic vinyl substituent at the C‐7 position has been achieved. The synthetic methodology is based upon the palladium‐catalyzed cross coupling of a 7‐chloro‐1,8‐naphthyridine with an appropriately substituted orga

ISSN:0022-152X    

DOI:10.1002/jhet.5570280133

出版商:Wiley‐Blackwell    

年代:1991

数据来源: WILEY

摘要:

AbstractThe reaction of the 1,2‐diazepino[3,4‐b]quinoxalines2a,bor3a,bwithN‐bromosuccinimide/water resulted in ring transformation to give the 1,4‐dihydro‐4‐oxopyridazino[3,4‐b]quinoxalines4a,b,

ISSN:0022-152X    

DOI:10.1002/jhet.5570280134

出版商:Wiley‐Blackwell    

年代:1991

数据来源: WILEY

摘要:

AbstractThe synthesis of the 12‐methyl derivative of a novel heterocyclic ring system, namely benzo[h][1]benzothieno[2,3‐c][1,6]naphthyridine (8) was prepared by photocyclization of 3‐chloro‐N‐(2′‐methyl‐4′‐quinolyl)benzo‐[6]thiophene‐2‐carboxamide (5) to 12‐methylbenzo[h][1]benzothieno[2,3‐c][1,6]naphthyridin‐6(5H)‐one (6). Chlorination of6afforded 6‐chloro‐12‐methylbenzo[h][1]benzothieno[2,3‐c][1,6]naphthyridine (7) which upon dechlori

ISSN:0022-152X    

DOI:10.1002/jhet.5570280135

出版商:Wiley‐Blackwell    

年代:1991

数据来源: WILEY

摘要:

AbstractTwo previously unknown thienopyridopyridazine ring systems, thieno[2′,3′:5,6]pyrido[2,3‐d]pyridazine‐5,8,9(4H,6H,7H)‐trione (4) and thieno[3′,2′:5,6]pyrido[2,3‐d]pyridazine‐4,5,8(6H,7H,9H)‐trione (10) were synthesized and their chlorination reactions with phosphorus oxychlorid

ISSN:0022-152X    

DOI:10.1002/jhet.5570280136

出版商:Wiley‐Blackwell    

年代:1991

数据来源: WILEY