ISSN:0022-152X    

DOI:10.1002/jhet.5570160801

出版商:Wiley‐Blackwell    

年代:1979

数据来源: WILEY

摘要:

AbstractThe multi‐step synthetic procedures to prepare a number of 2,3,4,5‐tetrahydro‐1H‐benzazepine derivatives 1 through a series of intermediates are described. The condensation of arylaldehydes2with 2‐nitropropanes3gave nitroalcohols4which were reduced to alcohol amines5. The condensation of5with arylacetaldehydes6gave imino derivatives7which on reduction with borohydride gave secondary amines8. By employing different methods, alcohol amines5were condensed with arylacetic acids9to give amides10which were then reduced to amines8. On treatment with mineral acids, amines8were cyclized to the target compounds1. Biological activities of1are also briefly

ISSN:0022-152X    

DOI:10.1002/jhet.5570160802

出版商:Wiley‐Blackwell    

年代:1979

数据来源: WILEY

摘要:

AbstractThe mass spectra of some 7‐methyl, 7‐chloro and 6‐earbethoxythiazolo[3,2‐a]pyrimidin‐5‐ones were studied (2,3,4). The electron impact fragmentation patterns of these compounds showed their relatively high stability and their similar mode of decomposition. Certain differences were observed among the three classes of compounds, due to the nature of the substituent on the pyri

ISSN:0022-152X    

DOI:10.1002/jhet.5570160803

出版商:Wiley‐Blackwell    

年代:1979

数据来源: WILEY

摘要:

AbstractMalononitrile (I) reacted with thioglycolic acid to yield the thiazolin‐4‐one derivatives II or III depending on the molar ratio of the reactants. Compound II reacted with benzaldehyde in refluxing pyridine to yield the arylidene derivative IV. On the other hand, the benzylidine bis derivative VIII was obtained when II was reacted with benzaldehyde in refluxing ethanol. The structure of IV was establishedviaits synthesis from the reaction of benzylidenemalononitrile (VI) and thioglycolic acid in refluxing acetic acid. Similar to II, compound III condensed with benzaldehyde to yield the benzylidene derivative

ISSN:0022-152X    

DOI:10.1002/jhet.5570160804

出版商:Wiley‐Blackwell    

年代:1979

数据来源: WILEY

摘要:

AbstractDetailed experimental procedures are given for the preparation of the stereoisomeric (E)‐ and (Z)‐methyl‐α‐hydroxy and α‐methoxyimino‐4‐nitro‐1H‐imidazole‐1‐acetates and of the related acids. (Z)‐Isomers have been prepared by synthesis. (E)‐Isomers have been obtained only by photoisomerization. Decarboxylation of the acids left the corresponding aldehydes which are ideal compounds for structural studies and

ISSN:0022-152X    

DOI:10.1002/jhet.5570160805

出版商:Wiley‐Blackwell    

年代:1979

数据来源: WILEY

摘要:

AbstractL'étude théorique des réactions citées dans le titre a été abordée en utilisant une méthode perturbationelle. Les résultats des calculs permettent de retrouver les orientations préférentielles expérimentales de la réaction lorsqu'elles correspondent à des différences d'énergie de stabilisat

ISSN:0022-152X    

DOI:10.1002/jhet.5570160806

出版商:Wiley‐Blackwell    

年代:1979

数据来源: WILEY

摘要:

AbstractSome 7‐melhyl‐substituted‐2,1‐benzisoxazoles and cyclopropanobenzofurazan oxides are synthesized and characterized by their elemental and spectral a

ISSN:0022-152X    

DOI:10.1002/jhet.5570160807

出版商:Wiley‐Blackwell    

年代:1979

数据来源: WILEY

摘要:

AbstractReduction followed by cyclization of (Z)‐methyl 3‐(6‐azido‐3‐chloro‐1‐methyl‐4‐oxo‐1,4‐dihydropyridazin‐5‐yl)‐2‐methylacrylate (I) to pyrido[2,3‐c]pyridazines by treatment with triethyl phosphite or hydrazine hydrate as the reducing agents is described. Compound I was also reductively cyclized with sodium borohydride. Treatment of I with concentrated sulfuric acid gave 8‐chloro‐3,6‐dimethyl‐2,5‐dioxo‐5,6‐dihydro‐2H‐pyrano[2,3‐d] pyridazine (VII) which also could be synthesized by another independent

ISSN:0022-152X    

DOI:10.1002/jhet.5570160808

出版商:Wiley‐Blackwell    

年代:1979

数据来源: WILEY

摘要:

AbstractStarting from the readily available 2‐substituted‐4‐formylselenazoles and 2‐substituted‐4‐formylthiazoles, a series of substituted‐pyrrolo[3,2‐d]selenazoles and substituted‐pyrrolo[3,2‐d|‐thiazoles were

ISSN:0022-152X    

DOI:10.1002/jhet.5570160809

出版商:Wiley‐Blackwell    

年代:1979

数据来源: WILEY

摘要:

AbstractThe conversion of heterocyclic amines into the corresponding azides or tetrazoloazines under phase transfer reaction conditions is described. It was found that this transformation is limited ordy to aminopyridine (1a‐d) aminoisoquinoline (1e) and 2‐aminobenzothiazole (1f) derivatives, while other heterocyclic amines (1g‐w) could not be transformed under these condi

ISSN:0022-152X    

DOI:10.1002/jhet.5570160810

出版商:Wiley‐Blackwell    

年代:1979

数据来源: WILEY