ISSN:0022-152X    

DOI:10.1002/jhet.5570230201

出版商:Wiley‐Blackwell    

年代:1986

数据来源: WILEY

摘要:

AbstractThe rhodium catalysed reduction of a 2,5‐disubstitued pyrrole5occurred selectively with thecisaddition of hydrogen. The resultingcis‐pyrrolidine was either cyclized without epimerization in refluxing toluene to the pyrrolizine7or with epimerization in refluxing acetic acid to the pyrrolizi

ISSN:0022-152X    

DOI:10.1002/jhet.5570230203

出版商:Wiley‐Blackwell    

年代:1986

数据来源: WILEY

摘要:

AbstractIn studies related to the synthesis of 2‐deamino chromophores of actinomycin by reaction of nitrous acid in fluoroboric acidviadiazotization of the 2‐amino group in the chromophore, the unknown fluorescent product is identified as the symmetrical phenoxazinone by cmr and

ISSN:0022-152X    

DOI:10.1002/jhet.5570230204

出版商:Wiley‐Blackwell    

年代:1986

数据来源: WILEY

摘要:

Abstract5‐Hydroxy‐2‐hydroxymethyl‐4‐pyridone (1) and 5‐hydroxy‐2‐hydroxymethyl‐1‐methyl‐4‐pyridone (2) reacted with arenediazonium salts to give 6‐arylazo‐substituted compounds3a‐dand4a‐d, respectively. Compounds3a‐dwere methylated with diazomethane to afford 6‐arylazo‐2‐h

ISSN:0022-152X    

DOI:10.1002/jhet.5570230205

出版商:Wiley‐Blackwell    

年代:1986

数据来源: WILEY

摘要:

Abstract4‐Amino‐5‐arylpyrimidines1react with diethyl alkylmalonates2to give pyrimido[1,6‐a]pyrimidines4in satisfactory yields. A possible mechanistic scheme and the spectral data of the reaction products are di

ISSN:0022-152X    

DOI:10.1002/jhet.5570230206

出版商:Wiley‐Blackwell    

年代:1986

数据来源: WILEY

摘要:

AbstractCrystals of 5‐phenylbarbituric acid,2, are monoclinic, space group C2/c. There are 8 molecules in the unit cell of dimensions a = 20.218(3), b = 7.477(1), c, = 12.443(2), β = 111.54° and V = 1749.6(4) Å3. Full‐matrix least‐squares refinement has reached R = 0.039. This is the first barbiturate reported to exist in the enol form in the solid state. There is extensive hydrogen bonding between adjacent molecules which gives rise to very dense crystals. The13C‐nmr spectroscopy shows that2exists in both enol and keto forms inDM

ISSN:0022-152X    

DOI:10.1002/jhet.5570230207

出版商:Wiley‐Blackwell    

年代:1986

数据来源: WILEY

摘要:

AbstractThe total synthesis of a novel benzazepine, 4,5,7a,8‐tetrahydro‐1,2‐dimethoxyphenanthro[10,1‐bc]azepin‐6(7H)‐one is described. Of crucial importance to the preparation of this material was a regiospecific Beckmann rearrangement reaction and the development of an aryl‐aryl linkage by a photochemically induced coupling. Details of successful and attempted methodology

ISSN:0022-152X    

DOI:10.1002/jhet.5570230208

出版商:Wiley‐Blackwell    

年代:1986

数据来源: WILEY

摘要:

Abstract1,3‐Dimethyluracil (1), a versatile synthon for the synthesis of various heterocycles, reacted readily with 3‐aminopyrazoles2in sodium ethoxide to give pyrazolo[1,5‐a]pyrimidines3. Under similar conditions, 3‐aminopyrazoleC‐nucleosides4and the synthon1gave a mixture of pyrazolo[1,5‐a]pyrimidineC‐nucleosides, which was separated on a silica gel column. Attempts to remove the protecting groups yielded pyranose derivative10. Another synthon 1,3‐dimethyl‐5‐azauracil and 3‐aminopyrazoles12gave pyrazolo[1,5‐a]triazines13. In a similar reaction with 3‐aminopyrazoleC‐nucleosides4gave the corresponding pyrazolo[1,5‐a]

ISSN:0022-152X    

DOI:10.1002/jhet.5570230209

出版商:Wiley‐Blackwell    

年代:1986

数据来源: WILEY

摘要:

AbstractNew proton‐ionizable macrocyclic polyether ligands containing the 4‐pyridone subcyclic unit have been prepared by reacting 4‐THP blocked‐2,6‐pyridinedimethanol with various oligoethylene glycol ditosylates. The 18‐crown‐6 ligand containing the 4‐pyridone subcyclic unit,4, forms stable complexes with alkali metal and organic ammonium cations. The crystal structure of4proves the 4‐pyridone structural unit. The crystal structure of the potassium thiocyanate complex of4is also reported and shows the complex to contain the 4‐h

ISSN:0022-152X    

DOI:10.1002/jhet.5570230210

出版商:Wiley‐Blackwell    

年代:1986

数据来源: WILEY

摘要:

AbstractA series of macrocyclic polyether (crown) ligands containing the proton‐ionizable s‐triazole subcyclic unit were prepared by reacting the 1‐THP blocked 3,5‐bis(chloromethyl)‐1H‐1,2,4‐triazole with various oligoethylene glycols. The starting bis(chloromethyl)triazole is a vessicant and must be used with caution. Triazolo‐18‐crown‐6 (5) formed stable complexes with barium, strontium, copper and benzylammonium cations but not with potassium or lithium. The crystal structure of5showed the triazole proton to be on nitrogen 3 which is outside t

ISSN:0022-152X    

DOI:10.1002/jhet.5570230211

出版商:Wiley‐Blackwell    

年代:1986

数据来源: WILEY