ISSN:0022-152X    

DOI:10.1002/jhet.5570010301

出版商:Wiley‐Blackwell    

年代:1964

数据来源: WILEY

摘要:

AbstractThrough quaternization of an acetal of picolinaldehyde with suitable α‐haloalkylarenes, a number of acridizinium salts, having a substituent at themesoposition adjacent to nitrogen, have been prepared. Similarly, the ketal derived from α‐acetopyridine has been used to prepare the first acridizinium derivatives having methyl groups at both of themesoposi

ISSN:0022-152X    

DOI:10.1002/jhet.5570010302

出版商:Wiley‐Blackwell    

年代:1964

数据来源: WILEY

摘要:

AbstractThe synthesis of derivatives of the hitherto unreported 3,9‐diazaspiro[5,5]undecane has been accomplished. Starting from the dianhydride of methanetetraacetic acid or from N‐methyl‐4‐piperidone, synthetic paths have been developed which permit the preparation of either symmetrical or unsymmetrical deri

ISSN:0022-152X    

DOI:10.1002/jhet.5570010303

出版商:Wiley‐Blackwell    

年代:1964

数据来源: WILEY

摘要:

AbstractThe direct alkylation of 2,4,6‐trimethyl‐s‐triazine (I) has been effected by treating (I) with a series of alkyl halides using potassium amide in liquid ammonia as the condensing agent. The present method gives a simple, direct route to the preparation of unsymmetrically substituted trialkyl‐s‐

ISSN:0022-152X    

DOI:10.1002/jhet.5570010304

出版商:Wiley‐Blackwell    

年代:1964

数据来源: WILEY

摘要:

AbstractThe “abnormal” behavior of 4,6‐dimethyl‐2‐pyrimidinol towards nitrous acid has been clarified. The reaction between 4‐methyl‐2‐pyrimidinol and nitrous acid has been utilized as a new synthetic procedure for the preparation of several 2‐substituted 4‐pyrimidinecarboxylic acids. 2‐Hydroxy‐4‐pyrimidinecarboxylic acid has also been prepared from 4‐chloro‐2‐methylthiopyrimidineviathe trimethylammonium intermediate. 6‐Amino‐ and 6‐thio‐4‐pyrimidinecarboxylic acids have been readily prepared from the previously repor

ISSN:0022-152X    

DOI:10.1002/jhet.5570010305

出版商:Wiley‐Blackwell    

年代:1964

数据来源: WILEY

摘要:

AbstractThe hydrolysis of 12H‐benzoxazolo[2,3‐b]quinazolin‐12‐one (I) yields N‐(2‐benzox‐azolyl)anthranilic acid (III) and 3‐(2‐hydroxyphenyl)quinazoline‐2,4‐dione (IV). Unequivocal syntheses of both III

ISSN:0022-152X    

DOI:10.1002/jhet.5570010306

出版商:Wiley‐Blackwell    

年代:1964

数据来源: WILEY

摘要:

Abstract2‐Picoline N‐oxide and 2,6‐Lutidine N‐oxide have been acylated in good to high yields by reaction with a series of aliphatic, aromatic and heterocyclic esters using sodium amide in liquid ammonia as the condesin

ISSN:0022-152X    

DOI:10.1002/jhet.5570010307

出版商:Wiley‐Blackwell    

年代:1964

数据来源: WILEY

摘要:

AbstractA three‐step synthesis of 5‐hydroxyflavone in 80% yield from 2,6‐dihydroxyaceto‐phenone is described. The key step is a modification of the Baker‐Venkataraman rearrangement in which small amounts of water are deliberately introduced. Characterization of the primary rearrangement products, 1‐(2,6‐dinydroxyphenyl)‐3‐phenyl‐1,3‐propane‐dione, and 1‐(2‐benzoyloxy‐6‐hydroxyphenyl)‐3‐phenyl‐1,3‐propanedione, is reported. Application of the synthesis to 3,5‐dichloro‐2,6‐dihydroxyacetophenone gives a mixture of 6,8‐dichloro‐5‐hydroxyflavone and its 3‐benzoyl derivative. Infrared spectral data are presented for several intermediates and flavones, and indicate the utility of the previously described i

ISSN:0022-152X    

DOI:10.1002/jhet.5570010308

出版商:Wiley‐Blackwell    

年代:1964

数据来源: WILEY

摘要:

AbstractA series of triazinyl ketones has been prepared by acylating 2,4,6‐trialkyl‐s‐triazines and these ketones have been isomerized to 4‐acylamidopyrimidine derivatives. A possible mechanism for this isomerization is su

ISSN:0022-152X    

DOI:10.1002/jhet.5570010309

出版商:Wiley‐Blackwell    

年代:1964

数据来源: WILEY

摘要:

AbstractA series of pyrazylethylated derivatives of the type C4H3N2CH2CH2N= has been prepared in high yields by the reactions of vinylpyrazine with amines using methanolic acetic acid or metallic sodium as the catalyst.

ISSN:0022-152X    

DOI:10.1002/jhet.5570010310

出版商:Wiley‐Blackwell    

年代:1964

数据来源: WILEY