摘要:

AbstractN‐Alkylazetidines were cleaved by nucleophilic reagents under moderate conditions to give the corresponding 3‐substituted‐propylamines. The additions were subject to acid catalysis and also proceeded slowly under alkaline S N 2c

ISSN:0022-152X    

DOI:10.1002/jhet.5570060301

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractA compound formulated in the literature as 4‐hydroxylaminocoumarin is now recognized to be the isomeric 1,2‐benzisoxazole‐3‐acetic acid. Therefore, a preceding paper by the authors describing this acid is proved incorrect due to inexact data in the previous literature on the preparation of 3‐methyl‐1,2‐

ISSN:0022-152X    

DOI:10.1002/jhet.5570060302

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractThe carbonyl group in the title compounds undergoes a number of reactions typical of ketones but in general is less reactive than a typical ketone. Reaction with hydrazine leads to reduction of the 5,6‐bond rather than reaction at the carbonyl group. Reduction of the carbonyl group gives rise to a rather inert carbinol. The carbonyl group appears to exert little influence on typical reactions at the 5,6‐posit

ISSN:0022-152X    

DOI:10.1002/jhet.5570060303

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractThe reaction of 2,2,4,4‐tetramethyl‐1,3‐cyclobutanedione with various nucleophiles has been demonstrated to be dependent on the reaction conditions, steric factors and the nucleophilicity of the attacking species. In the reaction with primary amines the intermediate has been established as theN‐substituted imine which is hydrolyzed to the corresponding amide in the presence of water. The reaction of diamines with the dione has been shown to be a method of synthesizing 2‐substituted imidazolines and 1H‐4,5‐dihyd

ISSN:0022-152X    

DOI:10.1002/jhet.5570060304

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractEleven phenazines were identified as fermentation products of a bacterium. They included the previously unknown 2,9‐dihydroxyphenazine‐1‐carboxyIic acid (4), 1,8‐phenazinediol‐1()‐oxide (5) and 8‐amino‐1‐phenazinol (6) as well as phenazine‐1,6‐dicarboxylic acid (1),9‐hydroxyphena‐zine‐1‐carboxylic acid (2) and 1,8‐phenazinediol (3) not isola

ISSN:0022-152X    

DOI:10.1002/jhet.5570060305

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractThe synthesis of a series of methyl‐substituted 8‐phenyl‐1,8‐diazabicyclo[4.3.0]nonanes is described. The preferred conformations of these compounds have been assigned on the basis of the 2850‐2500 cm−1region of their infrared spectra and of the geminal coupling constant of the C‐9 me

ISSN:0022-152X    

DOI:10.1002/jhet.5570060306

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractPyrolytic cyclization of a‐ and β‐methadol methiodides affordedcisandtransisomers of 2‐ethyl‐3,3‐diphenyl‐5‐methyltetrahydrofuran, respectively. Catalytic hydrogenation of 2‐ethyli‐dene‐3,3‐diphenyl‐5‐methyltetrahydrofuran yielded thecisand trans isomers in a 2:1 ratio. The nmr spectra of these and structurally related compounds have been analyzed in terms of a half‐chair conformation for 2‐ethyl‐5‐methyl, 2‐ethyl, and 5‐methyl derivatives. An envelope conformation has been suggested for the com

ISSN:0022-152X    

DOI:10.1002/jhet.5570060307

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractA 1:1 adducl of 2‐pyrone and nitronium fluoroborate has been delected by nmr and is a possible precursor of 5‐nitro‐2‐pyrone, a subsequently formed product. From comparison of the nmr spectra of the 1:1 adduct and 2‐methoxypyrylium fluoroborate, the adduct is believed to be the pyrylium fluoroborate derived from nitration of the carbonyl oxygen of

ISSN:0022-152X    

DOI:10.1002/jhet.5570060308

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractThree different 3,4‐diaeylfuroxans (1) are shown to give 3‐substituted‐l‐phenyl‐4,5‐dioximino‐2‐pyrazolines (2) upon reaction with phenylhydrazine. The compounds2were dehydrated to 6‐sul)stituted‐4‐phenyl‐4H‐pyrazolo[3,4‐c]furazans. (3) and thermally converted to 3‐substituted 5‐imino‐4‐oximino‐1‐phenyl‐2‐pyrazolines (6). The compounds 1 react with an

ISSN:0022-152X    

DOI:10.1002/jhet.5570060309

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY

摘要:

AbstractThe condensation of 1,2‐dialkyl‐3‐pyrazoIidinones (1) with a series of aldehydes, ketones and esters in the presence of sodium hydride is described. Alkylation of I with several alkyl bromides gave 4‐alkyl substitution products in modest yield and reaction of 1,2,4‐trimethyl‐3‐pyrazolidinone with n‐butyl bromide gave a 4,4‐dialkylation product. Compound 1 reacted with aryl Grignard reagents to form 3‐aryl‐3‐pyrazoIines whereas the corresponding products were not realized in the case of alkyl Grignards. The reduction of a single example of 1 as well as the reduction of two 3‐pyrazolines to pyraz

ISSN:0022-152X    

DOI:10.1002/jhet.5570060310

出版商:Wiley‐Blackwell    

年代:1969

数据来源: WILEY