摘要:

AbstractThis review article describes syntheses and reactions of 1,2‐oxazetidines that have an oxo or (substituted) imino group attached to either C‐3 or C‐4. The rare case of a bifunctional derivative is also treated. In a final chapter, spectroscopic properties are sur

ISSN:0022-152X    

DOI:10.1002/jhet.5570300301

出版商:Wiley‐Blackwell    

年代:1993

数据来源: WILEY

摘要:

AbstractA convenient synthesis of a new heterocycle, 5,6,7,8‐tetrahydropyrido[2,1‐b]purin‐10‐one1was described. 4‐Amino‐N‐(5‐chloropentanoyl)‐5‐imidazolecarboxamide3awas successively cyclized to1with polyphosphoric acid at 150°. Methylation of1under basic condition proceeded selectively atN‐1 to affo

ISSN:0022-152X    

DOI:10.1002/jhet.5570300302

出版商:Wiley‐Blackwell    

年代:1993

数据来源: WILEY

摘要:

AbstractA convenient one pot synthesis of ethyl 3,4‐dihydro‐2‐methyl‐3‐oxo‐2H‐1,4‐benzoxazine‐2‐carboxylates and 3,4‐dihydro‐2‐methyl‐3‐oxo‐2H‐pyrido[3,2‐b]‐1,4‐oxazine‐2‐carboxylates and their conversion into th

ISSN:0022-152X    

DOI:10.1002/jhet.5570300303

出版商:Wiley‐Blackwell    

年代:1993

数据来源: WILEY

摘要:

AbstractThe synthesis of 8‐substituted and unsubstituted 6H,11H‐indolo[3,2‐c]isoquinolin‐5‐ones/thiones3a‐cand4a‐cand their derivativesviz, ethyl (8‐substituted‐6H,11H‐indolo[3,2‐c]isoquinolin‐5‐on‐6‐yl)acetates5a‐c, (8‐substituted‐6H,11H‐indolo[3,2‐c]isoquinolin‐5‐on‐6‐yl)acetyl hydrazides6a‐c, 3,5‐disubstituted‐pyrazoles7a‐cand8a‐c, 3‐substituted‐pyrazol‐5‐ones9a‐cand 5‐(8‐substituted‐6H,11H‐indolo[3,2‐c]isoquinolin‐5‐on‐6‐yl)methyl‐1,3,4‐oxadiazole‐2‐thiones10a‐c, also ethyl (8‐substituted‐11H‐indolo[3,2‐c]isoquinolin‐5‐ylthio)ace‐tates11a‐c, (8‐substituted‐11Hindolo[3,2‐c]isoquinolin‐5‐ylthio)acetyl hydrazides12a‐c, 3,5‐disubstituted‐pyrazoles13a‐cand14a‐c, 3‐substitu

ISSN:0022-152X    

DOI:10.1002/jhet.5570300304

出版商:Wiley‐Blackwell    

年代:1993

数据来源: WILEY

摘要:

Abstract9,9a‐Dihydro‐2,9a‐dimethyl‐4‐oxo‐4H‐benz[f]indole‐3‐carboxylic acid, methyl ester was formed in varying amounts from the Friedel‐Crafts‐based synthesis of benzoylpyrrole calcium channel activators. The structure of this by‐product was determined using two‐dimensional long‐range1H‐13C heteronuclear correlated

ISSN:0022-152X    

DOI:10.1002/jhet.5570300305

出版商:Wiley‐Blackwell    

年代:1993

数据来源: WILEY

摘要:

AbstractPyrroles are powerful nucleophiles in the reaction with dialkyl sulfoxides and trimethylchlorosilane (TMCS) or trimethylbromosilane (TMBS), affording sulfonium salts or halo derivatives, generally in good yields.

ISSN:0022-152X    

DOI:10.1002/jhet.5570300306

出版商:Wiley‐Blackwell    

年代:1993

数据来源: WILEY

摘要:

AbstractReaction between some naphtho[2,1‐b]pyrans and 1,1‐diphenylethene affords 9,9‐diphenyl‐1,9,10,10a‐tetrahydro‐2H‐phenaleno[

ISSN:0022-152X    

DOI:10.1002/jhet.5570300307

出版商:Wiley‐Blackwell    

年代:1993

数据来源: WILEY

摘要:

AbstractMichael addition of DBU on diethyl maleate and subsequent cyclization of the adduct afforded a tricyclic derivative which was susceptible to react further with a second molecule of unsaturated diester.

ISSN:0022-152X    

DOI:10.1002/jhet.5570300308

出版商:Wiley‐Blackwell    

年代:1993

数据来源: WILEY

摘要:

Abstractcis‐4‐(Sulfomethyl)piperidine‐2‐carboxylic acid was obtained in 22% overall yield from 4‐(hydroxymethyl)‐pyridineviatheo‐silylN‐oxide and trimethylsilylcyanide. Thecisconfiguration of5was unambiguously assigned by 200 MHz1H nmr and c

ISSN:0022-152X    

DOI:10.1002/jhet.5570300309

出版商:Wiley‐Blackwell    

年代:1993

数据来源: WILEY

摘要:

AbstractReacting 1‐hydroxy‐2‐phenylindole with nitrosobenzene, 2‐phenyl‐3‐phenylimino‐3H‐indole 1‐oxide(1)is produced in only one of the two possible diastereomers. The latter reacts withtert‐butylmagnesium chloride and benzylmagnesium chloride giving, after oxidation, the corresponding aminoxyls which show the same configuration of the phenylimino group at C‐3 as in1. This has been demonstrated by means of nmr spectros‐copy and X‐ray crystal structure and represents an unexpecte

ISSN:0022-152X    

DOI:10.1002/jhet.5570300310

出版商:Wiley‐Blackwell    

年代:1993

数据来源: WILEY