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1. |
Phospholes. The aromaticity problem |
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Journal of Heterocyclic Chemistry,
Volume 13,
Issue 1,
1976,
Page 1-12
Alan N. Hughes,
Daniel Kleemola,
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摘要:
AbstractNewer techniques of phosphole synthesis, particularly those which lead to simple phospholes substituted with active functional groups, are briefly surveyed. A detailed account of chemical, physico‐chemical, spectroscopic and theoretical studies related to the phosphole aromaticity problem is given and the present conflicting position is discusse
ISSN:0022-152X
DOI:10.1002/jhet.5570130101
出版商:Wiley‐Blackwell
年代:1976
数据来源: WILEY
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2. |
The chemistry of 1,2,5‐thiadiazoles V. Synthesis of 3,4‐diamino‐1,2,5‐thiadiazole and [1,2,5] thiadiazolo[3,4‐b]pyrazines |
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Journal of Heterocyclic Chemistry,
Volume 13,
Issue 1,
1976,
Page 13-22
Andrew P. Komin,
Marvin Carmack,
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摘要:
AbstractTheo‐diamine, 3,4‐diamino‐1,2,5‐thiadiazole (2), was synthesized from 3,4‐dichloro‐1,2,5‐thiadiazole (3) hy three methods. Aqueous glyoxal cyclized2into [1,2,5]thiadiazolo[3,4–6]‐pyrazine (14). 3,4‐Dichloro‐1,2,5‐thiadiazole 1,1‐dioxide (18) reaeted with2to give 1,3‐dihydro‐bis[1,2,5]thiadiazolo[3,4‐b:3′,4′‐e]pyrazine 2,2‐dioxide (19). The reaction of2with selenium oxyehloride led to [1,2,5]selenadiazolo[3,4‐c] [1,2,5]thiadiazole (12). Ring closure of 2,3‐diaminoquinoxaline (4) with thionyl chloride or selenium oxychloride gave [1,2,5]thiadiazolo‐[3,4‐b]quinoxaline (21) and [1,2,5]selenadiazolo[3,4‐b]quinoxaline (22), respectively. Sulfurous acid reduced21to the 4,9‐dihydro derivative23, which was reoxidized to21with chloranil. Aqueous hase hydrolyzed21to4viathe hydrated intermediate24. Aqueous glyoxal cyclized4to the covalent hydrate of pyrazino[2,3‐b]quinoxaline (26),27, which was dehydrated to26. Compound26underwent rapid addition of two
ISSN:0022-152X
DOI:10.1002/jhet.5570130102
出版商:Wiley‐Blackwell
年代:1976
数据来源: WILEY
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3. |
Chemical properties ofN‐Benzoylimines of quinazoline, quinoxaline, and phthalazine |
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Journal of Heterocyclic Chemistry,
Volume 13,
Issue 1,
1976,
Page 23-28
Yasumitsu Tamura,
Yasuyoshi Miki,
Keiko Nakamura,
Masazumi Ikeda,
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摘要:
AbstractReactions of 1‐benzoylimino‐4‐phenylquinazolinium (I), 1‐benzoylimino‐3‐phenylquinox‐alinium (II), and 3‐benzoylimino‐1‐phenylphthalazinium betaines (III) with nucleophiles (hydroxide and cyanide ions) and 1,3‐dipolarophiles (acetylenic esters and maleimides) were investigated. Heating I in aqueous alkali gave 3‐phenylindazole, while similar treatment of II and III resulted in the formation of 1‐benzoylamino‐2‐oxo‐3‐phenylquinoxaline and 2‐benzoylamino‐1‐oxo‐4‐phenylphthalazine, respectively. Reaction of II and III with cyanide ion afforded 2‐cyano‐3‐phenylquinoxaline and 1‐cyano‐4‐phenylphthalazine in high yields, respectively. 1,3‐Dipolar cycloaddition reactions of I and III with dimethyl acetylenedicarboxylate and ethyl propiolate afforded primary 1:1 cycloadducts, while the reaction of II with dimethyl acetylenedicarboxylate gave a product which is formed by ring opening of a primary adduct. The reaction of I‐III withN‐methyl andN‐phenylmaleimides afforded the corresponding primary 1:1 cycloadducts in high yields, whose ster
ISSN:0022-152X
DOI:10.1002/jhet.5570130103
出版商:Wiley‐Blackwell
年代:1976
数据来源: WILEY
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4. |
Studies on the syntheses of heterocyclic compounds. Part DCXLIV. Catalytic reduction of homoproaporphine related compounds |
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Journal of Heterocyclic Chemistry,
Volume 13,
Issue 1,
1976,
Page 29-31
Tetsuji Kametani,
Keiichiro Fukumoto,
Fumio Satoh,
Kazuo Kigasawa,
Hideo Sugi,
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摘要:
AbstractHydrogenation of the homoproaporphine (IV) over platinum oxide gave a mixture of the cyclohexanols VIIa and VIIb. In contrast, reduction of IV on palladium provided the cyclo‐hexanone VI, which was also obtained from VIIb by oxidation. Treatment of the cyclohexanols VIIa and VIIb under hydrogen on platinum oxide afforded the same mixture of VIIa and VII
ISSN:0022-152X
DOI:10.1002/jhet.5570130104
出版商:Wiley‐Blackwell
年代:1976
数据来源: WILEY
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5. |
The synthesis of indazolesvia2,3‐dihydroindazoles |
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Journal of Heterocyclic Chemistry,
Volume 13,
Issue 1,
1976,
Page 33-39
Gladys S. Zenchoff,
Armin Walser,
R. Ian Fryer,
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摘要:
AbstractThe preparation and oxidation of 2,3‐dihydroindazoles to 1H, 2Hor 3H‐indazoles is described. A method for the synthesis of indazole 2‐oxides has been found. Oxidation of 2‐acetyl‐2,3‐dihydro‐3,3‐disubstituted indazoles5aand5cgave quinoid compounds20a, 20b, 24aand24b, which could be isomerized to 3H‐indazoles upon removal of the acetyl group. A quinoid compound21was also obtained on treatment of5awith t
ISSN:0022-152X
DOI:10.1002/jhet.5570130105
出版商:Wiley‐Blackwell
年代:1976
数据来源: WILEY
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6. |
1,8‐Naphthyridines. Part I. Synthesis of some trifluoromethyl‐1,8‐naphthyridine derivatives |
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Journal of Heterocyclic Chemistry,
Volume 13,
Issue 1,
1976,
Page 41-42
Eva Eichler,
Clarence Stanley Rooney,
Haydn Windsor Richard Williams,
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摘要:
AbstractThe synthesis of some 2‐amino‐1,8‐naphthyridine derivatives substituted in the 5‐ and/or 7‐positions with trifluoromethyl is described along with their conversions to the corresponding 1,8‐naphthyridin‐2(1H)ones. A modified procedure for oxidizing electron‐deficient heterocyclic compounds to theirN‐ox
ISSN:0022-152X
DOI:10.1002/jhet.5570130106
出版商:Wiley‐Blackwell
年代:1976
数据来源: WILEY
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7. |
1,8‐naphthyridines. Part II. Synthesis of some 3‐pyridyl‐5,7‐di(trifluoromethyl)‐1,8‐naphthyridin‐2(1H)ones |
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Journal of Heterocyclic Chemistry,
Volume 13,
Issue 1,
1976,
Page 43-44
Eva Eichler,
Clarence Stanley Rooney,
Haydn Windsor Richard Williams,
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摘要:
AbstractEthyl 2‐amino‐4,6‐di(trifluoromethyl)nicotinate was prepared and its use as an intermediate in the synthesis of two 3‐pyridyl‐5,7‐di(trifluoromethyr)‐1,8‐naphthyridin‐2(1H)ones is presented. A dimer of 2‐amino‐4,6‐di(trifluoromethyl)nieot
ISSN:0022-152X
DOI:10.1002/jhet.5570130107
出版商:Wiley‐Blackwell
年代:1976
数据来源: WILEY
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8. |
New routes to aroylthiadiazolines and arylazothiazoles from phenylglyoxalyl bromide arylhydrazones and phenacyl thiocyanate |
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Journal of Heterocyclic Chemistry,
Volume 13,
Issue 1,
1976,
Page 45-49
A. Sami Shawali,
A. Osman Abdelhamid,
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摘要:
AbstractReaction of phenylglyoxalyl bromide arylhydrazones (III) with thiourea in ethanol produces 2‐amino‐4‐phenyl‐5‐arylazothiazoles (XI) instead of the expected 2‐benzoyl‐4‐aryl‐5‐imino‐Δ2−1,3,4‐thiadiazolines (V) obtained from III and potassium thiocyanate. Phenacyl thiocyanate (IV) couples with diazotized anilines to give V. The mechanisms of formation of V and XI from VI and III, respectively, are postulated. Nitrosation of V gives the correspondingN‐nitroso derivatives (VII), which decompose upon refluxing in xylene to give 2,4‐disubstituted Δ2−1,3,4‐thiadiazolin‐5‐ones (VIII). The thiadiazolines V give the respectiveN‐aeyl derivatives IX and X with acetic a
ISSN:0022-152X
DOI:10.1002/jhet.5570130108
出版商:Wiley‐Blackwell
年代:1976
数据来源: WILEY
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9. |
Rearrangement reactions of phenyl chloroformate derivatives of 2‐Hydroxyaminoacetanilides to hydantoins, ureas and hydantoie acid derivatives |
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Journal of Heterocyclic Chemistry,
Volume 13,
Issue 1,
1976,
Page 51-55
Stanley C. Hell,
George Conklin,
Ronald J. Mccaully,
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摘要:
AbstractAlkaline treatment of 2′‐benzoyl‐2‐(N‐carbophenoxy‐N‐hydroxyamino)‐4′‐chloroacetanilide (10) and its corresponding acetate6afforded respectively 5‐(2‐benzoyl‐4‐chlorophenyl)‐3‐hydroxy‐hydantoic acid (12) and 6‐chloro‐4‐phenylquinazolone (13). A study of the course of the reaction was carried out with the corresponding compounds that are devoid of the 2‐benzoyl group. An elucidation of the rearrangement is based on the isolation and independent sy
ISSN:0022-152X
DOI:10.1002/jhet.5570130109
出版商:Wiley‐Blackwell
年代:1976
数据来源: WILEY
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10. |
Selenium heterocycles. XIX. Synthesis of selenophenes and triarylbenzenes from 2,5‐diaryl‐1,4‐dithiin 1,1,4,4‐tetroxides |
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Journal of Heterocyclic Chemistry,
Volume 13,
Issue 1,
1976,
Page 57-60
I. Lalezari,
A. Shafiee,
A. Rashidbaigi,
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摘要:
AbstractMixtures of 2,5‐diaryl‐1,4‐dithiin 1,1,4,4‐tctroxides and selenium were subjected to heat and afforded 2,5‐diarylselenophenes. Pyrolysis of 2,5‐diaryl‐1,4‐dithiin 1,1,4,4‐tetroxides led to the formation of a mixture of 1,2,4‐ and 1,
ISSN:0022-152X
DOI:10.1002/jhet.5570130110
出版商:Wiley‐Blackwell
年代:1976
数据来源: WILEY
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