摘要:

This light microscopic investigation of 15 thoroughbred horses provided substantial evidence for the classification of equine laryngeal hemiplegia as a distal axonopathy. Morphologic and morphometric examinations were performed on resin embedded recurrent laryngeal nerves from control, subclinical and clinical laryngeal hemiplegic animals. In the latter group of animals some distal hindlimb nerves were also examined. A distally graded loss of myelinated fibres selectively affecting those of large diameter was demonstrated in both left and right recurrent laryngeal nerves. Morphologic evidence of similar pathological changes in long hindlimb nerves was also present. An explanation for the early involvement of thecricoarytenoideus lateralismuscle in the course of laryngeal hemiplegia, was offered by the demonstration of more large diameter fibres in the branch of the recurrent laryngeal nerve innervating it, thus making it more susceptible to the disease process.

ISSN:0048-0169    

DOI:10.1080/00480169.1986.35334

出版商:Taylor & Francis Group    

年代:1986

数据来源: Taylor

摘要:

The recurrent laryngeal nerves were examined by electron microscopy in five control, four subclinical and four clinical laryngeal hemiplegic horses. In addition, the peroneal nerve was examined in two horses in the latter group. The distally distributed loss of large myelinated fibres in the left recurrent laryngeal nerve seen by light microscopy was confirmed. In addition, active axonal pathology was found to be more evident than indicated by light microscopic investigations. The “onion bulb” formations observed indicated the repetitive nature of the damaging influence to nerve fibres. Although the pathological changes were most obvious in the distal left recurrent laryngeal nerve, alterations similar in type and distribution were present in other areas of the left and right nerves, and in the distal hindlimb nerves. The observation of fibres with inappropriately thick myelin sheaths relative to their axonal calibre, was confirmed statistically by determining the regressions of axis cylinder perimeter against the number of myelin lamellae.

ISSN:0048-0169    

DOI:10.1080/00480169.1986.35335

出版商:Taylor & Francis Group    

年代:1986

数据来源: Taylor

ISSN:0048-0169    

DOI:10.1080/00480169.1986.35338

出版商:Taylor & Francis Group    

年代:1986

数据来源: Taylor

ISSN:0048-0169    

DOI:10.1080/00480169.1986.35339

出版商:Taylor & Francis Group    

年代:1986

数据来源: Taylor

ISSN:0048-0169    

DOI:10.1080/00480169.1986.35340

出版商:Taylor & Francis Group    

年代:1986

数据来源: Taylor

ISSN:0048-0169    

DOI:10.1080/00480169.1986.35341

出版商:Taylor & Francis Group    

年代:1986

数据来源: Taylor