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| 11. |
Morphometric analysis ofMycobacterium tuberculosisinfection in mice suggests a genetic influence on the generation of the granulomatous inflammatory response |
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The Journal of Pathology,
Volume 166,
Issue 1,
1992,
Page 77-82
J. M. Orrell,
S. J. Brett,
J. Ivanyi,
G. Coghill,
A. Grant,
J. Swanson Beck,
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摘要:
AbstractThere is evidence in natural human disease and experimental infection in mice that host genetic factors influence susceptibility to infection withMycobacterium tuberculosisand the progress of the disease. In mouse models, both H‐2 and non‐H‐2 genes have been implicated. In this study, four inbred strains of mice (Balb/b, Balb/k, B10, B10.BR), selected for combinations of two different H‐2 haplotypes on two different non‐H‐2 backgrounds, were inoculated withM. tuberculosis, strain H37Rv, by intraperitoneal injection. The histological features of the granulomatous inflammatory response in the liver and lungs were investigated during the first 18 weeks of the infection. Granuloma fraction, mean granuloma area, bacillary load, and the density of acid‐fast bacilli within granulomata were measured. Animals of all four strains showed the same general pattern of infection with an early, and later self‐limiting, infection of the liver and delayed onset, but progressive, infection of the lung. The non‐H‐2 related genetic background appears to influence the morphology of the granulomatous inflammatory response. In comparison, H‐2 differences appeared to be s
ISSN:0022-3417
DOI:10.1002/path.1711660112
出版商:John Wiley&Sons, Ltd.
年代:1992
数据来源: WILEY
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| 12. |
Image analysis |
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The Journal of Pathology,
Volume 166,
Issue 1,
1992,
Page 83-87
Timothy J. Stephenson,
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ISSN:0022-3417
DOI:10.1002/path.1711660113
出版商:John Wiley&Sons, Ltd.
年代:1992
数据来源: WILEY
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| 13. |
Genital papillomaviruses and related neoplasms. C. P. Crum and G. J. Nuovo. Raven Press, New York, 1991. No. of pages: 240. Price: $102.50. ISBN: 0 88167 763 9 |
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The Journal of Pathology,
Volume 166,
Issue 1,
1992,
Page 89-90
D. Jenkins,
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ISSN:0022-3417
DOI:10.1002/path.1711660115
出版商:John Wiley&Sons, Ltd.
年代:1992
数据来源: WILEY
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| 14. |
Glomerular pathology. W. Lawler. Churchill Livingstone, Edinburgh, 1991. No. of pages: 208. Price: £60. ISBN: 0 443 04062 1 |
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The Journal of Pathology,
Volume 166,
Issue 1,
1992,
Page 90-91
A. Morley,
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ISSN:0022-3417
DOI:10.1002/path.1711660116
出版商:John Wiley&Sons, Ltd.
年代:1992
数据来源: WILEY
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| 15. |
International academy of pathology monograph: Pathology of reproductive failure. F. T. Kraus, I. Damjanov and N. Kaufman (Eds). Williams&Wilkins, London, 1991. No. of pages: 362. Price: £53.00. ISBN: 0 683 04782 5 |
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The Journal of Pathology,
Volume 166,
Issue 1,
1992,
Page 91-92
J. Pryse‐Davies,
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ISSN:0022-3417
DOI:10.1002/path.1711660117
出版商:John Wiley&Sons, Ltd.
年代:1992
数据来源: WILEY
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| 16. |
Introduction to the cellular&molecular biology of cancer, 2nd ed. L. M. Franks and N. M. Teich (Eds). Oxford University Press, Oxford, 1991. No. of pages: 558. Price: £22.50. ISBN: 0 19 854734 X |
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The Journal of Pathology,
Volume 166,
Issue 1,
1992,
Page 92-92
B. Gusterson,
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ISSN:0022-3417
DOI:10.1002/path.1711660119
出版商:John Wiley&Sons, Ltd.
年代:1992
数据来源: WILEY
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| 17. |
Announcement |
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The Journal of Pathology,
Volume 166,
Issue 1,
1992,
Page 93-93
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ISSN:0022-3417
DOI:10.1002/path.1711660120
出版商:John Wiley&Sons, Ltd.
年代:1992
数据来源: WILEY
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| 18. |
Masthead |
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The Journal of Pathology,
Volume 166,
Issue 1,
1992,
Page -
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ISSN:0022-3417
DOI:10.1002/path.1711660101
出版商:John Wiley&Sons, Ltd.
年代:1992
数据来源: WILEY
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