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| 11. |
Release of Brain Amino Acids During Hyposmolar Stress and Energy Deprivation |
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Journal of Neurosurgical Anesthesiology,
Volume 8,
Issue 2,
1996,
Page 159-168
Tor Haugstad,
Iver Langmoen,
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摘要:
The release of 10 amino acids from rat hippocampal slices during exposure to hyposmotic stress or energy deprivation was measured by high-performance liquid chromatography. Exposing the slices to hyposmotic stress by lowering extracellular NaCl caused a 10-fold release of taurine (p < 0.01) and over a twofold increase of γ-aminobutyric acid (GABA) and glutamate (p < 0.01). These changes were reversed by mannitol. Exposure to combined glucose and oxygen deprivation (energy deprivation) caused a 50-fold increase in the release of GABA, a 40-fold increase in glutamate release (p < 0.01), and a twofold to sixfold increase in taurine, aspartate, glycine, asparagine, serine, and alanine release (p < 0.05) but no change in glutamine. Energy deprivation increased the water content by 21%. Mannitol blocked this increase and further enhanced the release of glutamate and aspartate (p < 0.01) but not of GABA. The permissivity of the amino acids was plotted against the pI (pH at isoelec-tric point) and hydropathy indexes. Energy deprivation increased the permissivity in the following order: acidic > neutral > basic. Among neutral amino acids, permissivity increased with increasing hydrophobicity. These results indicate that the mechanisms of amino acid release are different during cerebral ischemia and hyposmotic stress.
ISSN:0898-4921
出版商:OVID
年代:1996
数据来源: OVID
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| 12. |
Fever in acute stroke worsens prognosisA prospective study |
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Journal of Neurosurgical Anesthesiology,
Volume 8,
Issue 2,
1996,
Page 169-169
Azzimondi G,
Bassein L,
Nonino F,
Fiorani L,
Vignatelli L,
Re G,
D'Alessandro R.,
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ISSN:0898-4921
出版商:OVID
年代:1996
数据来源: OVID
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| 13. |
Low‐molecular-weight heparin for the treatment of acute ischemic stroke |
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Journal of Neurosurgical Anesthesiology,
Volume 8,
Issue 2,
1996,
Page 170-170
Kay R,
Wong K,
Yu Y,
Chan Y,
Tsoi T,
Ahuja A,
Chan F,
Fong K,
Law C,
Wong A,
Woo J.,
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PDF (86KB)
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ISSN:0898-4921
出版商:OVID
年代:1996
数据来源: OVID
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| 14. |
Delayed post ischemic hypothermiaA six month survival study using behavioral and histological assessments of neuroprotection |
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Journal of Neurosurgical Anesthesiology,
Volume 8,
Issue 2,
1996,
Page 171-171
Colbourne F,
Corbette D.,
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PDF (85KB)
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ISSN:0898-4921
出版商:OVID
年代:1996
数据来源: OVID
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| 15. |
Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke t‐PA Stroke Study Group |
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Journal of Neurosurgical Anesthesiology,
Volume 8,
Issue 2,
1996,
Page 172-172
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PDF (86KB)
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ISSN:0898-4921
出版商:OVID
年代:1996
数据来源: OVID
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| 16. |
Trends in death associated with traumatic brain injury, 1979 through 1992 |
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Journal of Neurosurgical Anesthesiology,
Volume 8,
Issue 2,
1996,
Page 173-173
Sosin,
D Sniezek,
J Waxweiler,
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ISSN:0898-4921
出版商:OVID
年代:1996
数据来源: OVID
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| 17. |
Hypertonic SalineIs It Time? |
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Journal of Neurosurgical Anesthesiology,
Volume 8,
Issue 2,
1996,
Page 174-174
Patricia,
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ISSN:0898-4921
出版商:OVID
年代:1996
数据来源: OVID
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| 18. |
Hypertonic Saline as a Safe and Efficacious Treatment of Intracranial Hypertension |
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Journal of Neurosurgical Anesthesiology,
Volume 8,
Issue 2,
1996,
Page 175-177
Mark,
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ISSN:0898-4921
出版商:OVID
年代:1996
数据来源: OVID
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| 19. |
Salt, Starch, and Water on the Brain |
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Journal of Neurosurgical Anesthesiology,
Volume 8,
Issue 2,
1996,
Page 178-182
Randall,
Schell Richard,
Applegate Daniel,
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ISSN:0898-4921
出版商:OVID
年代:1996
数据来源: OVID
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| 20. |
International Symposium on Neurointensive Care and Neuroanaesthesia—Feb. 18–19, 1995—A Report |
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Journal of Neurosurgical Anesthesiology,
Volume 8,
Issue 2,
1996,
Page 183-184
Arvind,
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PDF (403KB)
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ISSN:0898-4921
出版商:OVID
年代:1996
数据来源: OVID
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