ISSN:0012-2823    

DOI:10.1159/000191554

出版商:S. Karger AG    

年代:1908

数据来源: Karger

摘要:

In a group of 16 patients, receiving chenic acid (20 mg/kg/day) and phenobarbital (60 mg/day) for gallstone dissolution, three patients were observed to develop a marked increase in serum levels of SGOT-SGPT and alkaline phosphatase without associated symptoms. Liver biopsy in one patient showed cellular infiltration with neutrophils and eosinophils, suggestive of a hypersensitivity reaction. Enzyme levels returned to normal, following cessation of chenotherapy, and a second biopsy 3 months later was normal. In that patient a challenge with chenic acid, at 250 mg/day, was again followed by a marked elevation in levels of SGOT-SGPT and alkaline phosphatase. These patients are the first to show marked elevation in liver enzyme levels during chenotherapy; the mechanism and significance are unclear.

ISSN:0012-2823    

DOI:10.1159/000197921

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000191555

出版商:S. Karger AG    

年代:1908

数据来源: Karger

摘要:

A method of obtaining linear plots of protein-flow data from human pancreatic ductal secretions is described. The protein concentration in pancreatic secretions, when related to flow rates in two individuals, gave similar regression lines, with the correlation coefficients of r = -0.97 and -0.98, respectively, and slopes m = -1.02 and -0.82.

ISSN:0012-2823    

DOI:10.1159/000197922

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

As it has been previously shown, the pancreatic secretory response to an intraduodenal infusion of oleic acid is increased in animals accustomed to daily ethanol consumption compared to matched controls. This action has been verified in dogs provided with a Thomas cannula and consuming 2 g kg-1 ethanol or not, daily since 3 years. An intravenous infusion of 0.75 mg kg-1 h-1 of atropine suppresses the difference between alcoholic and non-alcoholic animals. Therefore, the increased release of CCK-PZ in response to meal, which is characteristic of chronic alcoholic animals, is under cholinergic control.

ISSN:0012-2823    

DOI:10.1159/000197923

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

In subjects with Crohn’s disease and ulcerative colitis, an increased percentage of peripheral blood neutrophils reduces the dye nitroblue tetrazolium. This is probably a non-specific index of inflammatory activity. There is no evidence that defective neutrophil function, as measured by this test, contributes to granuloma formation in Crohn’s dise

ISSN:0012-2823    

DOI:10.1159/000197924

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

Duodeno-gastric reflux measured in 18 patients without gastrointestinal complaints showed a wide variation of regurgitation rates. Duodeno-gastric reflux was significantly diminished during duodenal acidification. The effect was more intense and lasted longer after olive oil infused intraduodenally, leading practically to a closed pylorus.

ISSN:0012-2823    

DOI:10.1159/000197925

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000191556

出版商:S. Karger AG    

年代:1908

数据来源: Karger

摘要:

The influence of a single intravenous glucose load on maximal gastric acid secretion in 25 healthy men when stimulated with pentagastrin was studied. Under the influence of hyperglycaemia, a highly significant decrease of maximal acid output was found. Moreover, in the gastric juice an increase of chloride and calcium concentrations was noted. On the other hand, the output of potassium, chloride and magnesium was lowered. The above differences were statistically significant.

ISSN:0012-2823    

DOI:10.1159/000197926

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000191557

出版商:S. Karger AG    

年代:1908

数据来源: Karger