ISSN:0012-2823    

DOI:10.1159/000192024

出版商:S. Karger AG    

年代:1909

数据来源: Karger

摘要:

Heidenhain pouch (HP) dogs were studied. After gastroduodenostomy (GD) gastric emptying time was unaffected, but cineradiography showed that the strength of the antral contractions diminished considerably, while the number of peristaltic waves increased. ‘Circus movements’ of the barium meal through the GD to the duodenum and back to the stomach through the pylorus occurred. No significant changes in food-stimulated HP acid secretion or serum gastrin response were observed. After parietal cell vagotomy (PCV) gastric emptying and motility was unaffected, but food-stimulated HP acid secretion and serum gastrin response increased significantly. After addition of a GD to PCV gastric emptying time decreased significantly but similar changes in antral motility occurred as after GD alone. The food-stimulated HP acid secretion and serum gastrin response became significantly reduced. Fasting HP acid secretion and serum gastrin concentration were not significantly altered by any of the surgical procedu

ISSN:0012-2823    

DOI:10.1159/000197978

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

The influence of luminal lactose and glucose on intestinal calcium transport was examined in vivo in normal post-weaned young rats. In situ segments of duodenum, midgut and ileum were perfused through the lumen for 1 h with an isotonic solution of 3.4 mM calcium containing radioactive isotopic 45Ca as tracer and additionally either 10 mM lactose or 10 mM glucose or, for the control group, no saccharide. Net absorption was measured by disappearance of luminal calcium; lumen-to-plasma flux was determined from the disappearance of tracer 45Ca. This concentration of luminal lactose or glucose had no direct effect on calcium transport under these steady state conditions.

ISSN:0012-2823    

DOI:10.1159/000197979

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000192026

出版商:S. Karger AG    

年代:1909

数据来源: Karger

摘要:

An in vitro rabbit gallbladder assay was used to demonstrate that almost 80 % of the CCK activity in the rat gut is found in the proximal third of the small intestine. Previous studies had shown that pancreatic enzyme secretion is controlled from this area of the intestine.

ISSN:0012-2823    

DOI:10.1159/000197980

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000192027

出版商:S. Karger AG    

年代:1909

数据来源: Karger

摘要:

Quantitative incorporation and esterification of (9–10) 3H palmitate into jejunal mucosa was studied in vitro comparatively on human biopsies and on everted rings of rat intestine following various incubation times. This procedure is fitted for investigation of the glycerophosphate pathway. Quantitatively the total uptake of palmitate was similar in man and rat. But the distribution among the various esterified fractions was different in animal and man and different again in coeliac disease. Notwithstanding incorporation of palmitate into triglyceride the fatty acid composition of mucosal triglyceride showed little or no modificatio

ISSN:0012-2823    

DOI:10.1159/000197981

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000192028

出版商:S. Karger AG    

年代:1909

数据来源: Karger

摘要:

Five patients with Zollinger-Ellison syndrome received metiamide per os in doses ranging from 600 to 1,200 mg/day for a minimum period of 2 weeks. Drug produced an inhibition of basal gastric acid secretion ranging from 5 to 100 % with relief of symptoms. Survey of patients during and after metiamide course showed sometimes a prolonged antisecretory effect up to 26 days after the end of treatment or, on the contrary, a reduced drug activity in spite of increasing doses.

ISSN:0012-2823    

DOI:10.1159/000197982

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:0012-2823    

DOI:10.1159/000192029

出版商:S. Karger AG    

年代:1909

数据来源: Karger