摘要:

Myoelectrical activity of the gastrointestinal tract has been studied in the postoperative period of 13 patients who underwent cholecystectomy. The recordings have been performed by means of extracellular electrodes which were implanted at the levels of stomach, jejunum, ileum and colon during the surgical procedure. The records showed that fast activity is always persistent while the basic electrical rhythm is greatly disorganized during the immediate postoperative period. Such a characteristic pattern of the electrical activity suggested that the lack of peristaltic and propulsive movements, always noted during this period, is not correlated with a disappearance of gastrointestinal contractions, but only with a disturbance in their coordination.

ISSN:0012-2823    

DOI:10.1159/000197944

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

19 patients with HBs Ag-positive fulminant hepatitis underwent exchange transfusions and anti-HBs-rich plasma infusions. Circulating HBs Ag disappeared in 17 cases. Circulating anti-HBs detected by RIA was higher in cases with liver regeneration. There was no correlation between circulating anti-HBs level and the amount of anti-HBs-rich plasma administered. Recovery was observed in 36% of the cases and liver regeneration in 47%. As the beneficial effect of such a treatment is not yet evident, a controlled trial should require pairing of patients with respect to the number of exchange transfusions and amount of real or placebo anti-HBs.

ISSN:0012-2823    

DOI:10.1159/000197945

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

Buffalo strain male and female rats were given methylazoxymethanol acetate (20 % solution) intraperitoneally 20 mg/kg body weight weekly for 9 weeks, and killed 27 weeks later. Carcinomas of the large intestine, predominantly in the descending colon, developed in some of the rats. The incidence was higher in male than in female rats. Polypoid carcinomas were observed more often in male rats and sessile carcinomas with metastases in the female rats. Carcinomas were not observed in organs other than the large intestine.

ISSN:0012-2823    

DOI:10.1159/000197946

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

Using 85Sr-labelled microspheres as nonabsorbable markers, the effect of age on gastrointestinal propulsion motility was determined in conscious rats. There was no significant correlation between the gastric emptying rate or the propulsion motility of the small intestine and the age of the rats. However, the transit time of the intestinal content in the caecum in adult (17- to 20-month-old) rats was about fivefold the value found in weanling (19-day-old) rats. Also the transit time of the large intestine was found to be prolonged by about 70 % during the life span investigated.

ISSN:0012-2823    

DOI:10.1159/000197947

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

Effects of L-glutamine on gastric lesion models in rats and guinea pigs were studied. Shay ulceration in rats was not inhibited by oral L-glutamine. Although stress-induced gastric lesions in intact rats were not inhibited by L-glutamine, a strong antagonism of gastric lesions was induced in pylorus-ligated rats under the same stress by the amino acid. Histamine-induced gastric lesions in intact rats and guinea pigs were also markedly inhibited by L-glutamine. L-Glutamine inhibited the gastric lesions in rats induced by compound 48/80 but not significantly. Reserpine- or serotonin-induced gastric lesions in rats were not affected by L-glutamine. The mechanism of L-glutamine protection was discussed.

ISSN:0012-2823    

DOI:10.1159/000197948

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

In cats with gastric fistulae and Heidenhain pouches, the effect of acid entering the duodenum on secretion of acid, pepsin, and mucus from the Heidenhain pouch during maximal acid stimulation with pentagastrin or histamine, was studied. Duodenal acidification produced stimulation of pepsin and mucus secretion comparable to that induced by exogenous hormones (secretin and the combination of secretin with cholecystokinin). In addition, duodenal acidification caused an increase in acid secretion, thus suggesting that, in addition to secretin and cholecystokinin, a factor that stimulates acid secretion was also released by acid.

ISSN:0012-2823    

DOI:10.1159/000197949

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

New studies have permit to reevaluate the importance of the digestive tract in each of the mechanisms regulating cholesterol turnover. Particularly, the role of the digestive tract in the rat cholesterol synthesis was underestimated. Is there a similar situation in man?

ISSN:0012-2823    

DOI:10.1159/000197950

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

Gastric albumin clearance studies were carried out in 26 patients with alcoholic cirrhosis and in 10 control subjects. The mean clearance was significantly higher in patients than in control subjects. An increased protein gastric loss in cirrhotic patients was observed only in presence of gastritis. The presence or absence of distended esophageal varices did not influence the protein loss.

ISSN:0012-2823    

DOI:10.1159/000197951

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

High levels of glutamic acid and normal levels of glutamine were found in the blood of all but one of ten patients with carcinoma of the pancreas. No changes of the concentration in blood of these two amino acids were observed in 49 patients suffering from several diseases including malignant tumours. Although the mechanism of the rise of serum glutamic acid is difficult to explain at present, it may have some diagnostic value.

ISSN:0012-2823    

DOI:10.1159/000197952

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

The influence of propranolol, 50 μg/kg administered intravenously, on the gastrin concentration during sham feeding and after a test meal was studied in eight normal subjects. β-Adrenergic blockade had no inhibitory effect on the gastrin response to feeding. Sham feeding did not provoke a significant rise of serum gastrin concentration; however, in three subjects a definite gastrin response occurred in the presence of β-adrenergic blocka

ISSN:0012-2823    

DOI:10.1159/000197953

出版商:S. Karger AG    

年代:1976

数据来源: Karger