摘要:

The localization of S-antigen, the soluble, uveitogenic, 51 kDa protein of the retina has been studied. Highly specific rabbit anti-bovine S-antigen antiserum reacted predominantly with the outer segment layer of the photoreceptor cells of rat retina in the indirect immunofluorescence technique, provided that the tissue was fixed by perfusion of the light adapted animal.More detailed information was obtained by immuno-electron microscopy using the same fixation technique and Protein A-coated gold particles for labeling. S-antigen was found to be predominantly bound to the rod outer segment plasma membranes and to the discs. The possible implication of this localization is discussed in view of the function of S-antigen.

ISSN:0271-3683    

DOI:10.3109/02713688508999970

出版商:Taylor&Francis    

年代:1985

数据来源: Taylor

摘要:

Clinical Ophthalmology by J.J. Kanski Butterworth&Co., Ltd., Kent, England, 1984

ISSN:0271-3683    

DOI:10.3109/02713688508999971

出版商:Taylor&Francis    

年代:1985

数据来源: Taylor