摘要:

AbstractThein vitrobehavior of a number of Au–Fe precipitation‐hardenable alloys have been investigated in distilled water and in Ringer's solution (simulating the extracellular body fluids) by the open‐circuit potential versus time method. Thein vivobehavior of these materials as muscle implants has been studied by conventional histopathological and histochemical techniques. Optical and electron microscopic techniques have been used to study the extent and morphology of massive discontinuous precipitation as well as the mode of corrosion attack. A clear correlation has been established between the microstructural features presented by a given alloy and the time‐dependent open‐circuit potential andin vivocorrosion behavior. It can be concluded for this alloy system that the microstructure and the open‐circuit potential pattern may be taken to be a reasonable indication of the expectedin vivocorrosi

ISSN:0021-9304    

DOI:10.1002/jbm.820020402

出版商:John Wiley&Sons, Inc.    

年代:1968

数据来源: WILEY

摘要:

AbstractA careful solvent‐exchange procedure followed by liquid‐phase reaction of ethyleneimine with cellulose film in a nonpolar solvent provides an effective method of uniformly aminoethylating cellulose. The protonated aminoethyl groups on the cellulose can then ionically bind heparin, a blood anticoagulant. Heparinized aminoethylated cellulose tubing at low levels of aminoethylation (ca. 0.2–0.3% nitrogen) exhibited excellent antithrombogenic properties as well as excellent mechanical strength properties. Thein vitrotests demonstrated indefinitely long whole‐blood clotting times with normal thrombin times. In thein vivoexperiments, the heparinized aminoethylated cellulose tubing provided extended patency when implanted intravascularly in the regions of low blood flow rate (infra renal inferior vena cava of dogs). A principal use of this film is in the artificial

ISSN:0021-9304    

DOI:10.1002/jbm.820020403

出版商:John Wiley&Sons, Inc.    

年代:1968

数据来源: WILEY

摘要:

AbstractAcetylcholine esterase and the glucose oxidase–peroxidase systems have been entrapped in Silastic matrices. The entrapped acetylcholine esterase exhibited remarkable stability as compared to the free enzyme in solution. The glucose oxidase–peroxidase system indicated that consecutive reactions may be carried out by several enzymes entrapped within a single matrix. The effect of various inorganic materials on the entrapped enzymes was also investiga

ISSN:0021-9304    

DOI:10.1002/jbm.820020404

出版商:John Wiley&Sons, Inc.    

年代:1968

数据来源: WILEY

摘要:

AbstractRecently, a new successful prosthetic skin was reported from this laboratory. Utilizing the burned rat model, this prosthesis, controlled burn wound sepsis, prevented insensible water vapor loss and remained indefinitely. A prime factor necessary for the success of this prosthesis is its ability to adhere early to the recipient site. Thus, in order to investigate the underlying mechanisms of adherence and to be able to evaluate more closely different types of prosthetic skin, materials, and designs, a quantitative technique was developed using a modified Keil tester. The force (dynes/cm2) necessary to tear the prosthesis free was recorded on a direct writing apparatus. Tensile strength measurements of the prosthetic skin revealed a gradully increasing adherence of the tissue to the prosthesis. Initial values, days 2 through 5 post‐application, were low as recorded in dynes/cm2. The graft when removed on these days showed little or no gross fascial adherence, however, edge adherence steadily increased. After a few days the successful prosthesis could not be peeled without removing some tissue. Histologic studies show that by day 9 the prosthesis is an integral part of the subcutaneous tissue with foreign body giant cell reaction, ingrowth of of fibroblasts and collagen, and few inflammatory cells or bacteria. The adhesion values reveal that as the day post‐application increased the mean value in dynes/cm2increased from an initial 2.137 on day 2 to 8.019 on day

ISSN:0021-9304    

DOI:10.1002/jbm.820020405

出版商:John Wiley&Sons, Inc.    

年代:1968

数据来源: WILEY

摘要:

AbstractAnin vitroprocedure for measuring the affinity of silicone rubber balls for lipid is described. The method appears to duplicate weight and volume increases occasionally notedin vivo. Potential lipid absorption is shown to increase with degree of cure, and decrease with filler content.

ISSN:0021-9304    

DOI:10.1002/jbm.820020406

出版商:John Wiley&Sons, Inc.    

年代:1968

数据来源: WILEY

摘要:

AbstractIn order to monitor changes in thrombus size on prosthetic surfaces in dogs, a simple heat transfer measuring system was incorporated into a small right atrial sword which has been previously described.1This system provided a reliable and continuous measure of the amount of thrombus present on the sword. Initial thrombus formation was found to be complete within 45–90 min. Subsequent lysis of the thrombus was seem to occur in many cases after 8–12 hr of implantat

ISSN:0021-9304    

DOI:10.1002/jbm.820020407

出版商:John Wiley&Sons, Inc.    

年代:1968

数据来源: WILEY

摘要:

AbstractIt has been shown that the admixture of diacetins in the capacity of a diluent in the polymerization of hydrophilic poly(ethyleneglycol methacrylate) gels improves the properties of products used as soft denture liners, especially by inhibiting the volume changes caused by swelling, and by improving the mechanical properties of gels as well as the strength of bond between the gel and the basic material of the prosthesis.

ISSN:0021-9304    

DOI:10.1002/jbm.820020408

出版商:John Wiley&Sons, Inc.    

年代:1968

数据来源: WILEY

摘要:

AbstractThe results of our previous work on this subject1are supplemented by a follow‐up of more than 700 days. The results were very good, the prostheses drained off urine relably and were perfectly tolerated. No incrustations were observed, save in one case from this series where hydroenephrosis developed as a result of partial incrustatio

ISSN:0021-9304    

DOI:10.1002/jbm.820020409

出版商:John Wiley&Sons, Inc.    

年代:1968

数据来源: WILEY

ISSN:0021-9304    

DOI:10.1002/jbm.820020401

出版商:John Wiley&Sons, Inc.    

年代:1968

数据来源: WILEY