摘要:

SummaryThe life of a doctor dealing with family planning and the methods used is never dull. Until the end of October the possibility of a cancer risk, although often considered, was generally thought to be remote. All this has changed with the two publications in theLancetof 22 October 1983, and the objective of this meeting was to put this into perspective, and hopefully give guidance to prescribing doctors.

ISSN:1340-9654    

DOI:10.3109/01443618409074659

出版商:Taylor&Francis    

年代:1984

数据来源: WILEY

摘要:

SummaryI have an alarm radio by my bed, and on the morning of 21 October 1983 I was jerked into wakefulness by the second announcement in the early new headlines. It said:‘Reports out today show that pill takers run a greater risk of cancer’. That was how many doctors in Great Britain first heard about the two papers, by Professor Vessey and Dr Pike, in theLancet.

ISSN:1340-9654    

DOI:10.3109/01443618409074660

出版商:Taylor&Francis    

年代:1984

数据来源: WILEY

摘要:

SummaryIn judging possible adverse reactions, various criteria have been suggested. Table I consists of one such list of criteria. I particularly like this list because of its mention of the quality of the epidemiology. Items 2, 3 and 4 beg the question as to whether the evidence used is of high quality. A strong association in a poor quality study is meaningless.

ISSN:1340-9654    

DOI:10.3109/01443618409074661

出版商:Taylor&Francis    

年代:1984

数据来源: WILEY

摘要:

SummaryThis question as to whether the pill causes breast cancer is rather serious, and requires careful epidemiological studies.

ISSN:1340-9654    

DOI:10.3109/01443618409074662

出版商:Taylor&Francis    

年代:1984

数据来源: WILEY

ISSN:1340-9654    

DOI:10.3109/01443618409074663

出版商:Taylor&Francis    

年代:1984

数据来源: WILEY

ISSN:1340-9654    

DOI:10.3109/01443618409074664

出版商:Taylor&Francis    

年代:1984

数据来源: WILEY

摘要:

SummaryWhen we get a message we do not like, there is a strong temptation to shoot the messenger. There is a quotation—I am not sure where it comes from—that when an Englishman is thinking, he is really rearranging his prejudices. There is a danger that as family planners, we may react to the pros and cons that we have been considering in that way.

ISSN:1340-9654    

DOI:10.3109/01443618409074651

出版商:Taylor&Francis    

年代:1984

数据来源: WILEY

ISSN:1340-9654    

DOI:10.3109/01443618409074652

出版商:Taylor&Francis    

年代:1984

数据来源: WILEY

摘要:

SummaryOne of the problems in dealing with the hormone effects on the breast is that we have a number of specialists who talk about observations in their own field, but who also tend to extrapolate into other fields. I refer particularly to interpretations by clinicians, biochemists, pathologists and epidemiologists. The difficulty for those who talk about aspects that are not their field of specialisation is that they may lead to distortions. I am a histopathologist, and my daily activity is to judge tissue based on microscopic morphology which is a true record and not a distortion. The remarks that I shall make are based on morphological studies in breast tissue, to emphasise some points of relevance to the general topic that we are addressing today.

ISSN:1340-9654    

DOI:10.3109/01443618409074653

出版商:Taylor&Francis    

年代:1984

数据来源: WILEY

摘要:

SummaryOestrogenic hormones induce cellular growth and proliferation in organs bearing oestrogen receptors, namely the breast and the uterus. Progesterone or steroids with progestagenic action act through progestagen receptors which have been synthesised by involving the prior action of oestradiol. Progesterone antagonises the proliferation induced by oestrogens and acts in a synergistic way on the function of the cell.

ISSN:1340-9654    

DOI:10.3109/01443618409074654

出版商:Taylor&Francis    

年代:1984

数据来源: WILEY