摘要:

AbstractThis article describes the development of the application of capillary column GLC methods to steroids, prostaglandins and especially drugs and their metabolites in samples of biological origin. The wide variety – in terms of structures and pharmacological properties – of drugs now analyzed by capillary column GLC is made evident. Reasons for use of capillary rather than packed columns are given. The frequent use of and need for derivatization procedures prior to chromatography is emphasized. A bibliography of 83 references is included in the manuscr

ISSN:0935-6304    

DOI:10.1002/jhrc.1240030802

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1980

数据来源: WILEY

摘要:

AbstractA computer program is developed on a Hewlett‐Packard 3354 B Laboratory Automation System to eliminate background in gas and liquid chromatograms. Moreover undesired peaks, such as solvent peaks and spikes, can be excluded by selecting appropriate method parameters or by application of the integrator‐timed events directly affecting peak integration. Injudicious application of these codes deforms the chromatograms. Peaks can be labelled with retention times, areas or amou

ISSN:0935-6304    

DOI:10.1002/jhrc.1240030803

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1980

数据来源: WILEY

摘要:

AbstractA method for the HPLC separation of phosphatidylglycerol (PG), phosphatidylinositol (PI), phosphatidylcholine (PC), and sphingomyelin (SPH) was achieved using five in‐series columns packed with LiChrosorb, Partisil, and μ‐Porasil adsorbents, a solvent mixture of chloroform/methanol/ammonium hydroxide (50 : 36 : 6.7, by volume), and a Pye LCM2 Moving Wire (FID) detector. The same phospholipid mixture was also separated using four μ‐Porasil columns with the same eluent and detector. The latter conditions were found to be suitable for the analysis of phospholipids obtained after centrifuging, extraction, and precipitation of surface‐active lipid components of patient amniotic fluid collected at amniocentesis section. The lecithin/sphingomyelin (L/S) ratios, determined by the HPLC method, correlated well with those determined by the TLC technique in four normal pregnancies, whereas results of shake tests did not correlate too well with L/S ratios determined by the above two chromatographic methods. Besides the lecithin/sphingomyelin ratio, the present method was able to supply additional information: the concentrations of phosphatidylglycerol and phosphatidylinositol, for prediction of fetal lung maturity, and the palmitic acid content of amniotic fluid phosphatid

ISSN:0935-6304    

DOI:10.1002/jhrc.1240030804

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1980

数据来源: WILEY

摘要:

AbstractPMBF2, a pyrromethene pigment, can be used in gas chromatography. Because of its fluorescence, adsorption sites on glass columns and connections can be traced in situ. The compound can be employed to check the inertness of glass surfaces after deactivation procedures. Some applications are described.

ISSN:0935-6304    

DOI:10.1002/jhrc.1240030805

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1980

数据来源: WILEY

ISSN:0935-6304    

DOI:10.1002/jhrc.1240030806

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1980

数据来源: WILEY

ISSN:0935-6304    

DOI:10.1002/jhrc.1240030807

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1980

数据来源: WILEY

ISSN:0935-6304    

DOI:10.1002/jhrc.1240030808

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1980

数据来源: WILEY

ISSN:0935-6304    

DOI:10.1002/jhrc.1240030809

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1980

数据来源: WILEY

ISSN:0935-6304    

DOI:10.1002/jhrc.1240030810

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1980

数据来源: WILEY

ISSN:0935-6304    

DOI:10.1002/jhrc.1240030811

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1980

数据来源: WILEY