摘要:

We applied the direct immunoperoxidase method to estimate the susceptibility to IDU of 17 strains of the virus which were isolated from the patients with active epithelial lesions of herpetic keratitis. All the strains were found to be sensitive below the IDU concentration of 5 μg/ml. The findings obtained by this method were in good agreement with those by the fluorescent antibody technique. The present method is specific and simple. It offers clear‐cut interpretation and a permanent record of the resul

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1983.tb01483.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Chlamydia trachomatis were cultured from the conjunctiva of 8 newborn babies and 4 young adults' (age 20–30 years) affected with acute or therapy‐resistant chronic conjunctivitis. The newborn had acute purulent conjunctivitis noticed 4 to 12 days after birth. Five of them had been treated with topical chloramphenicol without effect before the diagnosis was made. They responded well to topical tetracycline ointment, but 3 relapsed. Two developed chronic conjunctivitis and respiratory tract infection, one under long time topical chloramphenicol treatment. The adults had a chronic, in 3 unilateral, conjunctivitis with pronounced follicularly (3) or papillary (1) conjunctival hypertrophy. Different degrees of pseudoptosis, micropannus and corneal infiltrates (in 3) were noticed. In the tear fluid, the quantitative pipette method revealed inflammation shown by neutrophilic granulocytes and lymphocytes with an appreciable predominance of the former in the newborn, while less so in the adults. In the newborn the diagnosis was easily made by culture and by demonstrating inclusions bodies in Giemsa‐stained conjunctival scrapings. In the adults the methods were less sensitive. A negative response to one culture does not preclude chlamydial infe

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1983.tb01484.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Screening of 189 Mongolian Japanese of both sexes in all age groups for scleral degenerations revealed presence of lipid deposits, especially round the anterior ciliary vessels, in 52%. The prevalence exceeds that among Caucasians in Denmark (N = 689), Eskimos in Greenland (N = 340), and Arabs in Jordan (N = 127), all examined by the same worker employing the same technique. Scleral plaques (well‐defined transparency anterior to horizontal muscle) is present in no more than 0.5% of Japanese. This phenomenon is likewise rare among Eskimos, but frequent among Caucasians. The causes of the geographic differences are discusse

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1983.tb01485.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

We have treated 54 eyes that were considered candidates for trabeculectomy with argon laser trabeculoplasty. One hundred burns were placed in the trabecular meshwork right in front of the scleral spur in the lower two quadrants. Average prelaser IOP was 26.2 mmHg and average postlaser IOP was 18.3 mmHg. Four eyes (7.4%) went to further surgery. Mean follow‐up time was 3.5 months. There were few complications. Most important was a transitory increase of IOP larger than 10 mmHg in 7 eyes (13.0%). There was one case of acute iridocycliti

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1983.tb01486.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

One hundred and eighty eyes of 161 patients with increased intraocular pressure resistant to medical therapy were treated with laser trabeculoplasty and were followed up for 18 to 42 months. In 97 eyes there was an exfoliation syndrome. In 93 of these there was an initial response. In 10 eyes pressure rose again during follow‐up. Of these, 7 were classed as late failures. 76 eyes had a primary open angle glaucoma or primary ocular hypertension, 58 responded to treatment. In one eye the effect worsened during follow‐up. In several eyes there was a deterioration of the visual field in spite of the fact that laser treatment resulted in good pressure reduct

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1983.tb01487.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

One hundred and thirty‐one phakic eyes of 109 patients with simple (52 eyes) and capsular (79 eyes) glaucoma were retrospectively followed at least for 12 months after laser trabeculoplasty (LTP). LTP was as effective in both groups with a success rate of 65% in simple glaucoma and 68% in capsular glaucoma. In half of the successful responders medication could be tapered. The mean intraocular pressure (IOP) reduction was greater in capsular glaucoma (37%) than in simple glaucoma (22 %). The average pressure reduction in successfully treated eyes obtained at one month was essentially the same throughout the entire time of observation with 27 patients followed for 18 months. In 2 eyes IOP increased 32 and 51 mmHg above the base line after LTP; no other severe complications were observe

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1983.tb01488.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Thirteen eyes of 12 patients with secondary glaucoma and 18 eyes of 18 patients with failed trabeculectomy were retrospectively followed at least for 12 months. The success rate in secondary glaucoma was 23% (3 of 13 eyes). Six eyes were operated, and 2 eyes were re‐lasered without success. In the eyes with failed trabeculectomy the success rate was 83% (15 of 18 eyes) with a 37% reduction of the mean intraocular pressure at one year. Medication could be tapered in 9 eyes and no eyes had to be re‐operated. Laser trabeculoplasty (LTP) seems to be highly effective in eyes with failed trabeculectomy while eyes with secondary glaucoma have a poor respo

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1983.tb01489.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

In a double‐masked randomised cross‐over study the effect of adding oral propranolol (40 mg × 2) to topical timolol‐treatment (0.5% × 2) was evaluated. Ten patients with glaucoma or ocular hypertension (totally 15 pathological eyes and 5 healthy) who had had topical timolol for at least 2 months received the coded oral treatment. A significant decrease of the intraocular pressure (3.68 ±0.72 SD,P<0.01) was observed in the timolol‐treated eyes after the addition of the masked treatment with placebo/pro‐pranolol. Also the non‐timolol‐treated fellow eyes had a significant decrease of the intraocular pressure. It is suggested that this additive effects depends on a loss of efficacy of the topical beta‐blocker caused by an increase in the number of beta‐receptors and that the oral beta‐blocker restores the degree of blocking to

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1983.tb01490.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

6‐Methoxy‐1,2,3,4‐tetrahydro‐β‐carboline (6‐MeO‐THBC) is a condensation product of 5‐methoxytryptamine and formaldehyde. It possesses diverse biochemical and pharmacological properties and has been suggested to act as a neuromodulator. 6‐MeO‐THBC has been shown to occur in various tissues including the retina in animals and human beings. The present results show that the mouse and rat retina as well as other tissues take up14C‐labelled 6‐MeO‐THBC injected intravenously or intravitreally. The retinal concentrations show a prompt rise after the injection and significant levels a

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1983.tb01491.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

A clinical analysis of 200 patients (307 eyes with optic disc drusen, 40 eyes with pseudopapilloedema without verified drusen, 53 normal fellow‐eyes) was performed to document the characteristic findings in pseudopapilloedema with and without verified drusen. In 4 eyes optic disc drusen accounted for diminished visual acuity. Papillary or peripapillary haemorrhages were found in 6.1 % of 347 eyes. Peripapillary pigment epithelial derangement was present in 29.7% of the eyes, mostly with superficial drusen. Subjective symptoms caused by drusen were very rare. Changes in the appearance of the optic discs with drusen during the years could be documented in 15% of 153 patients. There were 5 patients with pigmentary retinopathy. The most usual of coincident disorders was migraine in 21 patients. The visual field findings are analysed in a companion repor

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1983.tb01492.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY