摘要:

Retinal fluorescein angiography and colour fundus photography was performed in the one eye of 48 clinically healthy middle aged subjects, 21 females and 27 males, without ophthalmoscopically obvious fundus abnormalities. A region of retina 45° around the fovea was analysed for morphological elements in colour photographs, red‐free photographs and fluorescein angiograms. Subtle morphological elements, small and ‘large’ fluorescent spots, were noted in 20 out of 48 subjects (= eyes)(42%) during the early and middle phases of the fluorescein angiogram. In 15 subjects the number and location of fluorescent spots (n = 40) corresponded to spots in the colour and red‐free photographs. In 10 out of the 15 subjects (67%) with fluorescent spots the corresponding spots in the colour and red‐free photographs were indistinctly outlined. Fluorescent spots without corresponding spots in colour and red‐free photographs (n = 18) were found in 10 subjects. Thirtyeight per cent of all the fluorescent spots (n = 22) persisted with variable intensity in the late phases of the angiograms. Colour photographs disclosed variable numbers of yellowish spots in 34 subjects (71%). Sixty‐four per cent of the spots (71 our of 111 spots) in colour photographs could not be visualized by fluorescein angiography. These spots were characteristically distinctly outlined. The retinal spots were chiefly located in the upper and lower regions temporal to the fovea both in colour photographs (71% of the spots) and the fluorescein angiograms (62% of the spots). The occurrence of morphological elements of the retina did not correlate with age or smoking habits. The appearance of minor morphological elements in the retina of normal subjects seems to variate widely as assessed by fluorescein angiography and fundus colo

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1982.tb06726.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

A prototype of TV indirect ophthalmoscope (black‐and‐white type) was developed to enhance education in ophthalmology. Its weight is 450 g, and pictures obtained were fairly satisfactory. The authors have used this ophthalmoscope not only for practicing indirect iphthalmoscopy by students, but also as monitoring device during retinal surg

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1982.tb06727.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

The prevalence of partial sight and legal blindness was studied in 533 diabetics traced by prescriptions on insulin and oral hypoglycaemic agents (OHA) on the island of Falster (44 498 inhabitants). The prevalence of insulin‐treated diabetics (30 September 1980) was 0.52 per 1000 inhabitants and 0.72 per 1000 inhabitants of OHA‐treated patients. In the insulin‐treated group 106 patients had an onset age of diabetes below 30 years. Legal blindness occurred in 7.9% of 227 investigated insulin‐treated and in 4.9% of 306 OHA‐treated patients. Thus, the overall frequency of blindness in these 533 investigated diabetics was 6.2%. Partial sight was found in 4.9% of insulin‐treated and in 10.5% of OHA‐treated diabetics. In the insulin‐treated patients partial sight and legal blindness was caused by retinopathy (background and proliferative) in 81.8% and 84.8% of patients, respectively. Retinopathy contributed to partial sight in 46.8% and legal blindness in 80% of OHA‐treated diabetics. Proliferative retinopathy and background retinopathy caused visual loss in 48.4% and 36.4%, respectively, of legal blind diabetics. In diabetics with partial sight, background retinopathy was a more frequent cause of impaired vision (44.2% of the patients) than proliferative retinopathy (9.3% of the patients). In 50% of OHA‐treated patients with partial sight maculopathy without diabetic retinopathy (senile maculopathy) was the cause of visual impairment in contrast to 1% of insulin‐treated patients with partial sight. The severity of visual impairment was significantly associated with the duration of diabetes (>15 years), the current age (>50 years) and age at onset of diabetes (>30 years) in insulin‐treated group. Relation between duration of diabetes (>5 years) current age (>70 years) and a visual acuity 0.10 could be demonstrated in OHA‐treated patients. Impaired vision was more common among females in both the insulin‐ and OHA‐treated group. In the females no association appeared between the frequency of pregnancies and a visual acuity 0.33. In diabetics with nephropathy, gangrene or amputation impairment of vi

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1982.tb06728.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

In 30 diabetic patients with normal intraocular pressures a comparison of a long term (6 months) effect on eye tension of panretinal monocular xenon arc and argon laser photocoagulation was made. The applanating suction cup method was used for the simultaneous, bilateral IOP recordings. Photocoagulation with the xenon arc produced significant declines in IOP of 3.1 mmHg after one month and of 2.2 mmHg after 6 months. A significantly smaller decline in IOP (0.9 mmHg) was found after one month if the argon laser with retrobulbar anesthesia was used for the treatments. Photocoagulation performed with the argon laser without retrobulbar anesthesia produced no significant changes in IOP. There was no changes in outflow facility of aqueous humor.

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1982.tb06729.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

A method to determine fluorescein in human plasma is described. By aid of ultrafiltration a separation between fluorescein bound to plasma proteins and fluorescein free in the water is obtained. Both fractions are quantitated. Fluorescein is bound to plasma proteins. The protein binding is reversible, not sensitive to practically appearing changes in pH, temperature and gas tensions. For a normal person it appeared that at a total plasma concentration between (10‐6–10‐4) g·ml‐1approximately 15% was free while at a total concentration of 10‐3g·ml‐145% was free, pointing towards a limited amount of protein

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1982.tb06730.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

In connection with corpus vitreum fluorophotometric examinations fluorescein was injected iv and fluorescein in the blood stream was studied with respect to protein binding and elimination kinetics. It was shown by ultrafiltration that in blood obtained during the examination most of the fluorescein was protein bound, and only a minor fraction (10–20%) was free in the water phase. While the free fraction was approximately constant over a wide concentration range when studied in vitro the free fraction increased by a factor of about 2 during a 2 h examination period in vivo. The curve describing the elimination of fluorescein from blood showed a polyexponential decline course. The area under this curve showed only a small variation for the same normal person examined 3 times over a period of 6 months. The area under the bolus has a magnitude, which is 30–40% of that under the rest of the cu

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1982.tb06731.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Strabismus surgery with adjustable sutures of absorbable material was performed in 19 patients, aged 8–69 years, who had paralytic strabismus and/or were re‐operated. The ocular alignment was assessed at 1 week and 3–12 months post‐operatively. In 12 of the patients eye position was stable during that period. Eleven of them had good or moderate binocular vision. However, eye position changed over the follow‐up period in about half of the patients with poor binocular vision. No evidence was found for any muscle repositioning by mechanical stress during suture a

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1982.tb06732.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

An attempt was made to establish normal values for the total protein concentrations and the enzyme activities of LDH, MDH and PGI in the intraocular fluids of rats, guinea pigs, rabbits, cats, dogs, sheep, cattle, pigs, horses and humans. Remarkably little species differences were noted in 9 of the 10 mammals with vitreal enzyme activities falling into a narrow range between 8.4 U/l (PGI, horse) and 92.4 U/l (MDH, guinea pig). All species obeyed the sequence aqueous

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1982.tb06733.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

The bundle of rays from the chamber angle will pass the posterior surface of the contact‐glass at a large angle. This will result in considerable astigmatism. Different methods to reduce or eliminate the astigmatism are discusse

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1982.tb06734.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

A compilation of the records of all registered glaucoma patients in Gothenburg in the year of 1976 was analysed for the prevalence of glaucoma, the age distribution, the sex distribution, the presence of unilateral or bilateral disorder, and the age of onset of glaucoma. The glaucoma population consisted of 2776 individuals making and overall prevalence of 0.63%. There was no sex difference when comparison was made within each age group. A marked rise in prevalence was found in older age groups. Some problems in analysing and comparing mass data are discussed. A sample of this glaucoma population will be selected for further detailed investigation.

ISSN:1755-375X    

DOI:10.1111/j.1755-3768.1982.tb06735.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY