摘要:

elimination of gingival bleedinghas been related to a reduction in inflammation; however, histologic data are not available to support this association. The purpose of this study was to characterize the histology of interproximal gingiva that was converted from a bleeding to a nonbleeding state. An interproximal gingival biopsy was obtained from each of 32 patients, 15 of whom bled upon stimulation with a soft wooden interdental cleaner. The remaining 17 biopsies were obtained from sites which initially bled, but were converted to nonbleeding by scaling and interproximal plaque control. Specimens were processed for light microscopic evaluation and subjected to a morphometric analysis for various tissue components. Data from bleeding and “stopped bleeding” specimens were compared using analysis of covariance. The results indicated that “stopped bleeding” specimens had significantly less inflamed connective tissue. It was concluded that the conversion of a bleeding to a nonbleeding state corresponds with a histological reduction in the magnitude of the interproximal inflammatory lesion and provides a rationale, therefore, for the use of bleeding to monitor the effects of therapeutic methods.

ISSN:1049-8885    

DOI:10.1902/jop.1986.57.2.63

出版商:Wiley    

年代:1986

数据来源: WILEY

摘要:

the research expanding our knowledgeof the periodontally involved root surface and its treatment is reviewed. To improve communication in the clinic and classroom, definitions are suggested for the terms “scaling” and “root planing.” The objectives and limitations of root planing procedures are discussed.

ISSN:1049-8885    

DOI:10.1902/jop.1986.57.2.69

出版商:Wiley    

年代:1986

数据来源: WILEY

摘要:

tissue samples from three subjectswho had periodontal defects treated with a porous hydroxylapatite implant were investigated using light microscopy and scanning electron microscopy. The 3‐month specimen showed connective tissue infiltration through the pores and a narrow zone of bone formation present along the walls of the pores. At 4 months, continued evidence of bone deposition was present with osteocytes, osteoblasts and organization of collagen fibers apparent throughout the implant. The 6‐month implant had further evidence of continued bone formation with lamellar bone being the major component within the pores.

ISSN:1049-8885    

DOI:10.1902/jop.1986.57.2.76

出版商:Wiley    

年代:1986

数据来源: WILEY

摘要:

the feasibility of a new combined collagengel‐autolysed antigen‐extracted allogeneic bone implant was tested. Its effect on gaining new attachment in surgically created defects in four dogs was evaluated over 24 weeks. As controls, sites receiving implants of the bone implant alone, nonimplanted and untreated defects were also evaluated. The collagen gel encouraged ingrowth of regenerative tissue‐fibroblasts in the early stages of wound healing while the allogeneic bone induced new bone formation. The graft materials were bicompatible, technically manageable and clinically effective. From the present preliminary study, it was evident that the combined autolysed antigen‐extracted allogeneic bone‐collagen gel implant may offer advantages over the present implant materials and techniques currently used in the treatment of periodontal intrabony defects.

ISSN:1049-8885    

DOI:10.1902/jop.1986.57.2.84

出版商:Wiley    

年代:1986

数据来源: WILEY

摘要:

the relationship between the clinicalperiodontal status and the occurrence ofActinobacillus actinomycetemcomitans (A.a.)in 19 Finnish patients with localized juvenile periodontitis (LJP) was studied. Clinical examination included the Plaque Index, Gingival Index, suppuration, probing depth and bleeding on probing. The subgingival bacterial samples were taken from two diseased periodontal pockets with radiographic bone loss and two periodontal pockets exhibiting no radiographic alveolar bone loss. The results indicate thatA.a.was isolated in 17 (89%) patients, in 68% of the diseased and in 32% of the control periodontal sites. Supragingival plaque, marginal gingival inflammation, gingival bleeding on probing, and suppuration were found as frequently inA.a.‐positive as inA.a.‐negative diseased LJP pockets. It was concluded thatA.a.was frequently, but not always, detected in diseased LJP lesions. No association was found between the clinical status and the occurrence ofA.a.

ISSN:1049-8885    

DOI:10.1902/jop.1986.57.2.91

出版商:Wiley    

年代:1986

数据来源: WILEY

摘要:

three treatment regimens including localtetracycline delivery, systemic doxycycline and surgery plus systemic doxycycline were investigated in a localized juvenile periodontitis (LJP) population. Of the investigated treatments only surgery plus systemic doxycycline for 14 days was effective in eliminating or suppressingActinobacillus actinomycetemcomitans, an organism strongly associated with LJP lesions. While surgery plus antibiotics was the superior treatment, it appears that the possibility of reinfection or incomplete elimination of the organism exists. Careful long‐term follow‐up, including clinical and microbiological monitoring, is highly recommended in this periodontal population.

ISSN:1049-8885    

DOI:10.1902/jop.1986.57.2.94

出版商:Wiley    

年代:1986

数据来源: WILEY

摘要:

a case of prepubertal periodontitiswas observed and examined immunohistologically with peroxidase‐antiperoxidase staining. The patient was an 11‐year and 7‐month‐old Japanese girl, well‐developed and well‐nourished. Her parents were first cousins. Her chief complaint was the loosening and loss of the permanent teeth. There was a similar history of primary dentition. Her remaining permanent teeth were loosened with severe alveolar bone loss, but calculus deposit was minimal. Significantly, there was no palmar‐plantar hyperkeratosis. General examination showed normal data except for the increase of the immunoglobulin concentrations. In neutrophil function tests Chemotaxis was depressed, although phagocytosis, random migration and Superoxide production were within normal limits. Histologically, neutrophils were seen in the gingival tissue and other findings were also similar to those of adult periodontitis. In immunohistological examination, IgG‐bearing cells which mostly consisted of plasma cells predominated in the lesion. Considering the past history, the immunodeficiency and the absence of palmar‐plantar hyperkeratosis, the case was diagnosed as prepubertal periodontitis.

ISSN:1049-8885    

DOI:10.1902/jop.1986.57.2.100

出版商:Wiley    

年代:1986

数据来源: WILEY

摘要:

previous studies have shown thatmetronidazole is an effective chemotherapeutic agent in the treatment of certain types of periodontal disease. The purpose of this study was to assess, over 18 hours, the concentration of the drug in serum and gingival crevicular fluid after a single oral dose. Six female volunteers with gingivitis created by cessation of brushing for 2 weeks, took 250 mg of metronidazole orally. Micropipettes were used to collect 20μl of serum and 4 to 5μl of gingival fluid hourly for 8 hours, and at the 12th and 18th hours. Samples were assayed with a high pressure liquid Chromatograph. Mean drug levels in serum closely matched those reported by Stephen et al. (Br Dent Jl: 313, 1966) with polography. Mean serum drug levels peaked at 6.09μg/ml at the 2nd hour, and mean gingival crevicular fluid drug levels peaked at 3.62μg/ml at the 2nd and 7th hours. The drug was detectable in both fluids for up to 18 hours. Mean serum concentrations remained greater than mean gingival fluid concentrations at all time intervals, though the differences were not significant (P<0.05) as determined by a Hotelings' T2test. Using reported minimal inhibitory concentration values of metronidazole for various periodontopathogens, it was concluded that a single oral dose of metronidazole will deliver potentially inhibitory levels of the drug to the periodontium in serum and in gingival crevicular fluid.

ISSN:1049-8885    

DOI:10.1902/jop.1986.57.2.104

出版商:Wiley    

年代:1986

数据来源: WILEY

摘要:

this paper reviews developments inchemotherapeutic agents relative to their impact on clinical practice. These agents are discussed in terms of their effect on plaque, gingivitis, periodontitis, hypersensitive dentin and re‐attachment procedures. The paper also provides a perspective on delivery systems.

ISSN:1049-8885    

DOI:10.1902/jop.1986.57.2.108

出版商:Wiley    

年代:1986

数据来源: WILEY

ISSN:1049-8885    

DOI:10.1902/jop.1986.57.2.112

出版商:Wiley    

年代:1986

数据来源: WILEY