摘要:

Twenty‐four mandibular buccal classII furcation lesions in 12 subjects were treated with reconstructive periodontal therapy including citric acid root treatment and replaced flap surgery. Twelve (12) of the lesions received expanded polytetrafluoroethylene (ePTFE) membranes to cover the furcation entrance (ePTFE group) whereas the remaining 12 lesions received a connective tissue graft over the furcation (CTG group). Clinical assessments, including probing depth, probing attachment level, location of gingival margin, direct bone probing, and defect volume, were taken at baseline and at 12 months reentry. In the ePTFE group 30% of the defect volume filled with bone; 36% of the defects exhibited complete bone closure. In the CTG group 19% of the defect volume filled with bone and 18% of these defects exhibited complete bone closure. There were no meaningful clinical differences between treatment groups except in horizontal probing depth change (P≤0.05). This study suggests that connective tissue grafts and ePTFE membranes have comparable potential in supporting bone regeneration in mandibular Class II furcation lesions. Further clinical trials with larger numbers of patients and a longer evaluation period are needed to fully compare these procedures.J Periodontol 1993;64:1193–1198.

ISSN:1049-8885    

DOI:10.1902/jop.1993.64.12.1193

出版商:Wiley    

年代:1993

数据来源: WILEY

摘要:

The aim of the present studywas primarily to investigate if periodontal healing assessed by reduction in probing depth over time is significantly influenced by the initial degree of horizontal radiographic attachment loss and secondly to what degree any such relationship influenced the already established correlation between presence of a root canal infection and impaired marginal healing. The investigation was conducted as a retrospective study on 160 patients referred to a specialist periodontal clinic. The choice of variables was guided by an assumption that each variable either positively or negatively contributed to determine probing depth reduction. It was found that healing after scaling and root planing over time was significantly impaired with more advanced loss of radiographic attachment. Regardless of the extent of radiographic attachment loss, healing after scaling and root planing was also significantly impaired over time by the presence of a root canal infection.J Periodontol 1993;64:1199–1204.

ISSN:1049-8885    

DOI:10.1902/jop.1993.64.12.1199

出版商:Wiley    

年代:1993

数据来源: WILEY

摘要:

To investigate the contributionof genetic factors in the etiology of periodontal disease, questionnaire data were collected on 4,908 twin pairs included in the populationbased Virginia Twin Registry. A history of periodontal disease was reported in 420 individuals who were members of 116 monozygotic (MZ) and 233 dizygotic (DZ) twin pairs. The mean age at diagnosis in this sample was 31.4±0.7 years and was significantly earlier in females than males (30.1 vs. 33.0 years,P<0.025). Proband‐wise concordance rates were 0.38 for MZ and 0.16 for DZ twins. There were no differences in concordance rate between same and opposite‐sexed dizygotic twins. These findings provide evidence that genetic factors make an important contribution to risk for adult‐onset periodontal disease.J Periodontol 1993;64:1205–1208.

ISSN:1049-8885    

DOI:10.1902/jop.1993.64.12.1205

出版商:Wiley    

年代:1993

数据来源: WILEY

摘要:

Fibroblast heterogeneity in human periodontal tissueswas characterized by cloning and immuno‐histochemical techniques. Cell suspensions from primary cultures gingival (GF) and PDL fibroblasts (PF) were cloned. The relative intensity of double‐labeled immunofluorescence, using specific antibodies to the extracellular matrix (ECM) molecules collagen type I (CI), type III (CIII), and fibronectin (Fn), was measured by photometry. Most clones derived from either GF or PF showed positive intracellular staining for both CI and Fn, and CIII and Fn. However, there were variations in fluorescence intensity for CI and Fn, ranging from relatively weak to strongly positive. The fluorescence for CI and CIII was relatively weak in most isolated GF clones in contrast to their PF clones. These observations coupled with studies of growth and cellular morphology in individual clones suggest that: 1) GF and PF contain functionally heterogeneous subpopulations; and 2) the synthesis and expression of extracellular matrix molecules of GF may be essentially different from that of PF.J Periodontol 1993;64:1209–1218.

ISSN:1049-8885    

DOI:10.1902/jop.1993.64.12.1209

出版商:Wiley    

年代:1993

数据来源: WILEY

摘要:

Because of their antimicrobial and anti‐inflammatoryproperties, tetracyclines have been used systemically and locally in the treatment of periodontal disease. This study was done to evaluate the influence of doxycycline (De), a tetracycline, on fibroblast adherence to a protein coated surface and its cytotoxicity. Periodontal ligament derived fibroblasts (PLDFs) were either: 1) preincubated with Dc (0 to 100 μg/ml) and then allowed to adhere to a gelatin‐coated surface or 2) adherence was first established and then Dc added to the system. After an appropriate time the number of PLDFs adherent, released, or lysed was estimated by a lactic dehydrogenase (LDH) assay. Preincubation of PLDFs in 25 μg Dc/ml or higher concentrations significantly (P<0.01) reduced the number of adherent cells. Fifty μg Dc/ml and higher doses significantly (P<0.01) increased PLDFs cytotoxicity as measured by LDH release. The same trend was noted if PLDFs were allowed to adhere and then subjected to the drug. Microscopic observation of fluorescein diacetate/propidium iodide‐stained cells showed that attached‐spread cells pulled in, rounded up, and detached in proportion to the increased dose of Dc and the percentage of red‐stained cytotoxic cells rose in a similar manner. The data suggested that Dc can be cytotoxic and may inhibit PLDFs adherence and spread along a substratum.J Periodontol 1993;64:1219–1224.

ISSN:1049-8885    

DOI:10.1902/jop.1993.64.12.1219

出版商:Wiley    

年代:1993

数据来源: WILEY

摘要:

The purposes of this study were to determine if: 1) an association exists between cigarette smoking and signs of periodontal disease after controlling for the confounding variables of age, sex, plaque, and calculus; 2) the prevalence of 5 bacteria commonly associated with periodontal disease differs between smokers and non‐smokers; and 3) the presence of any of these bacteria or smoking are associated with a mean proximal posterior probing depth ≥ 3.5 mm. Plaque, calculus, gingivitis, and probing depth were measured at the proximal surfaces of all teeth in one randomly selected posterior dental sextant in 615 adults. Subgingival plaque was sampled from the same sites and assayed for the presence ofPorphyromonas gingivalis, Actinobacillus actinomycetemcomitans, Prevotella intermedia, Eikenella corrodens, andFusobacterium nucleatum. A subsample of non‐smokers (n = 126), who were similar to smokers (n = 63) with respect to age, sex, plaque, and calculus, was randomly drawn from the original sample. These two groups were then compared on the basis of clinical and microbial parameters. The results indicated that the odds of having a mean probing depth ≥ 3.5 mm were 5 times greater for smokers than the non‐smoker subsample (odds ratio = 5.3; 95% CI = 2.0 to 13.8). No statistically significant difference in the prevalence of any of the bacteria was found between smokers and the non‐smoker subsample. Based on logistic regression analyses of each of the 5 bacteria and smoking, mean probing depth ≥ 3.5 mm was significantly associated with the presence ofA. actinomycetemcomitans, P. intermedia, E. corrodens, and smoking (P<0.05). For this sample of medically healthy, middle‐aged adults, it is concluded that cigarette smoking is a stronger risk indicator for the presence of a mean posterior proximal probing depth ≥ 3.5 mm than any of the 5 bacteria.J Periodontol 1993;64:1225–1230.

ISSN:1049-8885    

DOI:10.1902/jop.1993.64.12.1225

出版商:Wiley    

年代:1993

数据来源: WILEY

摘要:

Porphyromonas gingivalis(P.gingivalis)is considered to be a pathogenic factor in adult or rapidly progressive periodontitis. The purpose of this study was to evaluate the distribution ofP. gingivalisin the dentition of adult periodontitis patients using a nonradioactive DNA probe, and to compare the presence ofP. gingivaliswith clinical parameters. Twelve adult periodontitis patients were examined. Subgingival plaque samples were taken from 4 sites of all the remaining teeth using a paper point. At the same time, probing depth and bleeding on probing (BOP) were also recorded. Plaque samples were investigated using a whole genomic DNA probe fromP. gingivalis(ATCC 33277) modified with bisulfite. The detection, percentage and amounts ofP. gingivalispresent were statistically compared with probing depth and BOP in each patient.P. gingivaliswas detected in all patients examined. The detection percentage was 35% of all sample sites. When the probing depth was over 4 mm or BOP was positive, the detection percentage ofP. gingivalissignificantly increased (P<0.01). As moreP. gingivaliswas identified, the percentage of sites with deep probing depth or that were BOP positive increased significantly (P<0.01). However,P. gingivaliswas also detected in clinically healthy sites, andP. gingivalisnegative sites with deep probing depth or that were BOP positive existed in the same patient. These results indicate thatP. gingivalisplay an important role, but is not the only microorganism responsible for adult periodontitis.J Periodontol 1993;64:1231–1237.

ISSN:1049-8885    

DOI:10.1902/jop.1993.64.12.1231

出版商:Wiley    

年代:1993

数据来源: WILEY

摘要:

The purpose of this studywas to evaluate patient postoperative pain experience and discomfort with and without the use of a periodontal dressing in combination with a 0.2% Chlorhexidine mouthwash after internal bevelled, full thickness, apically positioned flap procedure. Twenty‐four patients requiring comparable bilateral flap procedures were selected. Using a split‐mouth design, one site received a periodontal dressing while the other site did not. A 0.2% chlorhexidine mouthwash (10 ml for 1 minute twice daily) was prescribed postoperatively for all patients. Pain assessment was made according to a structured, categorized scale (0 = no pain; 1 = mild pain; 2 = moderate pain; and 3 = severe pain). Analgesic drug consumption was recorded during the first postoperative week. After at least a one‐month period, the second flap procedure was performed using the alternate postoperative treatment. At the conclusion of the trial, a self‐administered questionnaire on postoperative experience was administered. Results indicated a similar trend for mean pain scores as assessed by patients for both dressed and undressed sides during the 7‐day postoperative period. Statistical analysis revealed no significant differences between treatment groups with respect to frequency distribution of patients who did or did not take analgesics or the daily and total consumption of analgesic drops. Although patients with dressing frequently experienced eating difficulty, most stated a psychological feeling of protection and well‐being with its use.J Periodontol 1993;64:1238– 1242.

ISSN:1049-8885    

DOI:10.1902/jop.1993.64.12.1238

出版商:Wiley    

年代:1993

数据来源: WILEY

摘要:

Tomography is a radiographic processthat produces cross‐sectional images of bony structures within the body. The purpose of this study was to evaluate the accuracy of diagnostic measurements made by dental implant team members from linear tomograms of human cadaver mandibles. Five partially edentulous cadaver mandibles were radiographed using linear tomography (LT) and computer‐assisted tomography (CT). From the tomograms, each of four team members traced the perceived outer circumference of the mandible and the inferior alveolar canal. Tomogram tracings were compared to each other and to the equivalent CT cross‐sectional image to determine the precision of the measurements. One mandible was sectioned to verify the accuracy of the CT images. Repeated measures analysis of variance of the measurements made from the LT and CT scans showed significant statistical differences between team members. Multiple crosssectional views facilitated identification of the inferior alveolar canal in the majority of CT scans, whereas image blurring inherent to LT resulted in the inability of team members to identify the canal in 14% to 50% of the images. Volume averaging within the CT slice aperture was found capable of producing a magnification error of short dense objects. CT and LT must both be interpreted cautiously because of innate technique pecularities that can lead to measurement errors. The wide variation in interpretation of the linear tomograms and frequent inability to identify the inferior alveolar canal made this technique less valuable than the reformatted CT when planning dental surgical procedures.J Periodontol 1993;64:1243–1249.

ISSN:1049-8885    

DOI:10.1902/jop.1993.64.12.1243

出版商:Wiley    

年代:1993

数据来源: WILEY

摘要:

Gingival swellings are commonand most often associated with infection. A case due to the rare peripheral squamous odontogenic tumor is described. It is considered premature to regard peripheral odontogenic tumors as either hamartomatous or neoplastic, and close follow‐up of all such lesions is necessary.J Periodontol 1993;64:1250–1252.

ISSN:1049-8885    

DOI:10.1902/jop.1993.64.12.1250

出版商:Wiley    

年代:1993

数据来源: WILEY