ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02923.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02925.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

ABSTRACTFifteen dogs with signs of small and, or, large bowel disease that responded clinically to an exclusion diet were studied, using differential sugar absorption as an objective parameter of the mucosal response to the diet. Intestinal permeability and function were assessed by determining the urinary excretion ratios of lactulose/rhamnose and xylose/3‐O‐methylglucose, respectively, following oral administration of a mixture of these four sugars. Five dogs, all retrievers, were tentatively diagnosed as having dietary hypersensitivity, based upon resolution of clinical signs and normalisation of high intestinal permeability following an exclusion diet and recurrence of signs (in four of five dogs) upon challenge with the original diet. The fifth dog did not become symptomatic when challenged, but intestinal permeability increased. The remaining 10 dogs were diagnosed as having food intolerance, based upon clinical improvement on an exclusion diet, relapse on challenge with their original diet, but lack of improvement in intestinal permeability. These findings suggest that a differential sugar absorption test may be useful to determine the reasons for clinical response to exclusion diets. Demonstration of increased intestinal permeability with subsequent normalization following an exclusion diet may be useful in the diagnosis of dietary hypersensitivity, while persistent abnormalities in intestinal permeability are suggestive of underlying intestinal disease and food intolera

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02926.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02927.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02929.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02931.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

ABSTRACTThe role of the stratum corneum both as a barrier to water loss from the body and as a biological microenvironment is well recognised, although most discussion of these topics is expressed in qualitative terms. This paper describes the use of techniques for the measurement of some aspects of the skin microclimate, and their application to canine skin. The techniques used were the assessment of skin moisture, hygroscopicity and water‐holding capacity by measurement of skin electrical capacitance. Meaningful deductions regarding the water dynamics of certain skin sites can be drawn, and it was shown that significant differences in hydration exist between different skin sites. The techniques were also used to show that scaly skin is ‘drier’ than normal skin, and that the water dynamics of the non‐lesional skin of atopic dogs does not differ from that of norm

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02932.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02933.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

ABSTRACTA survey to establish the UK prevalence of the gene mutation causing the rod‐cone dysplasia type one (rcdl) form of generalised progressive retinal atrophy (gPRA) in Irish setters was carried out. The dogs were selected by members of two Irish setter breed societies to provide examples from most of the main breeding lines in the UK. A total of 210 Irish setters were tested and one bitch was found to be a carrier of the rcdl mutation. These results show that although a confirmed case of rcdl has not been reported in Irish setters in the UK for over a decade the gene is still present in the gene poo

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02934.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02935.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY